LOCUS HSU03397 1415 bp mRNA linear HUM 27-NOV-1994
DEFINITION Human receptor protein 4-1BB mRNA, complete cds.
ACCESSION U03397
VERSION U03397.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1415)
AUTHORS Alderson,M.R., Smith,C.A., Tough,T.W., Davis-Smith,T.,
Armitage,R.J., Falk,B., Roux,E., Baker,E., Sutherland,G.R.,
Din,W.S. and Goodwin,R.G.
TITLE Molecular and biological characterization of human 4-1BB and its
ligand
JOURNAL Eur. J. Immunol. 24 (9), 2219-2227 (1994)
PUBMED 8088337
REFERENCE 2 (bases 1 to 1415)
AUTHORS Alderson,M.
TITLE Direct Submission
JOURNAL Submitted (10-NOV-1993) Mark Alderson, Immunex Research and
Development Corp., 51 University St., Seattle, WA 98101, USA
FEATURES Location/Qualifiers
source 1..1415
/db_xref="H-InvDB:HIT000217496"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="T cell"
/tissue_type="peripheral blood"
CDS 120..887
/note="homology to the receptors for TNF and NGF; human
homolog of murine T-cell receptor 4-1BB protein;
transmembrane protein"
/codon_start=1
/product="4-1BB"
/protein_id="AAA53133.1"
/translation="MGNSCYNIVATLLLVLNFERTRSLQDPCSNCPAGTFCDNNRNQI
CSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMC
EQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGP
SPADLSPGASSVTPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRK
KLLYIFKQPFMRPVQTTQEEDGCSCRFPEEEEGGCEL"
misc_feature 531..533
/note="encodes potential glycosylation site"
misc_feature 564..566
/note="encodes potential glycosylation site"
misc_feature 678..758
/note="encodes transmembrane domain; amino acids 187-208"
BASE COUNT 385 a 332 c 333 g 365 t
ORIGIN
1 agtggaaagt tctccggcag ccctgagatc tcaagagtga catttgtgag accagctaat
61 ttgattaaaa ttctcttgga atcagctttg ctagtatcat acctgtgcca gatttcatca
121 tgggaaacag ctgttacaac atagtagcca ctctgttgct ggtcctcaac tttgagagga
181 caagatcatt gcaggatcct tgtagtaact gcccagctgg tacattctgt gataataaca
241 ggaatcagat ttgcagtccc tgtcctccaa atagtttctc cagcgcaggt ggacaaagga
301 cctgtgacat atgcaggcag tgtaaaggtg ttttcaggac caggaaggag tgttcctcca
361 ccagcaatgc agagtgtgac tgcactccag ggtttcactg cctgggggca ggatgcagca
421 tgtgtgaaca ggattgtaaa caaggtcaag aactgacaaa aaaaggttgt aaagactgtt
481 gctttgggac atttaacgat cagaaacgtg gcatctgtcg accctggaca aactgttctt
541 tggatggaaa gtctgtgctt gtgaatggga cgaaggagag ggacgtggtc tgtggaccat
601 ctccagccga cctctctccg ggagcatcct ctgtgacccc gcctgcccct gcgagagagc
661 caggacactc tccgcagatc atctccttct ttcttgcgct gacgtcgact gcgttgctct
721 tcctgctgtt cttcctcacg ctccgtttct ctgttgttaa acggggcaga aagaaactcc
781 tgtatatatt caaacaacca tttatgagac cagtacaaac tactcaagag gaagatggct
841 gtagctgccg atttccagaa gaagaagaag gaggatgtga actgtgaaat ggaagtcaat
901 agggctgttg ggactttctt gaaaagaagc aaggaaatat gagtcatccg ctatcacagc
961 tttcaaaagc aagaacacca tcctacataa tacccaggat tcccccaaca cacgttcttt
1021 tctaaatgcc aatgagttgg cctttaaaaa tgcaccactt tttttttttt ttttgacagg
1081 gtctcactct gtcacccagg ctggagtgca gtggcaccac catggctctc tgcagccttg
1141 acctctggga gctcaagtga tcctcctgcc tcagtctcct agtagctgga actacaagga
1201 agggccacca cacctgacta acttttttgt tttttgtttg gtaaagatgg catttcgcca
1261 tgttgtacag gctggtctca aactcctagg ttcactttgg cctcccaaag tgctgggatt
1321 acagacatga actgccaggc ccggccaaaa taatgcacca cttttaacag aacagacaga
1381 tgaggacaga gctggtgata aaaaaaaaaa aaaaa
//