LOCUS HSU03274 2016 bp mRNA linear HUM 25-FEB-1998
DEFINITION Homo sapiens biotinidase mRNA, complete cds.
ACCESSION U03274
VERSION U03274.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2016)
AUTHORS Cole,H., Reynolds,T.R., Lockyer,J.M., Buck,G.A., Denson,T.,
Spence,J.E., Hymes,J. and Wolf,B.
TITLE Human serum biotinidase. cDNA cloning, sequence, and
characterization
JOURNAL J. Biol. Chem. 269 (9), 6566-6570 (1994)
PUBMED 7509806
REFERENCE 2 (bases 1 to 2016)
AUTHORS Cole,H.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-1993) Cole H., Virginia Commonwealth University,
Human Genetics, 1101 East Marshall St., Rm 11-059 Sanger Hall,
Richmond, VA 22398-0033, USA
FEATURES Location/Qualifiers
source 1..2016
/db_xref="H-InvDB:HIT000217495"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="BTD2000"
/sex="male"
/cell_type="hepatocyte"
/tissue_type="liver"
/clone_lib="human liver cDNA"
CDS 36..1667
/EC_number="3.5.1.12"
/function="catalytic release of biotin from biocytin"
/codon_start=1
/product="biotinidase"
/protein_id="AAC04318.1"
/translation="MAHAHIQGGRRAKSRFVVCIMSGARSKLALFLCGCYVVALGAHT
GEESVADHHEAEYYVAAVYEHPSILSLNPLALISRQEALELMNQNLDIYEQQVMTAAQ
KDVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEVLQRLSC
MAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNLYFE
AAFDVPLKVDLITFDTPFAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAWMNQL
PLLAAIEIQKAFAVAFGINVLAANVHHPVLGMTGSGIHTPLESFWYHDMENPKSHLII
AQVAKNPVGLIGAENATGETDPSHSKFLKILSGDPYCEKDAQEVHCDEATKWNVNAPP
TFHSEMMYDNFTLVPVWGKEGYLHVCSNGLCCYLLYERPTLSKELYALGVFDGLHTVH
GTYYIQVCALVRCGGLGFDTCGQEITEATGIFEFHLWGNFSTSYIFPLFLTSGMTLEV
PDQLGWENDHYFLRKSRLSSGLVTAALYGRLYERD"
mat_peptide 159..1664
/product="biotinidase"
/EC_number="3.5.1.12"
/function="catalytic release of biotin from biocytin"
/experiment="experimental evidence, no additional details
recorded"
regulatory 1967..1972
/regulatory_class="polyA_signal_sequence"
BASE COUNT 500 a 493 c 498 g 525 t
ORIGIN
1 gccagctgga gcgttttcgg ggctgtaaag ggagaatggc gcatgcgcat attcagggcg
61 gaaggcgcgc taagagcaga tttgtggtct gcattatgtc tggagccaga agtaagcttg
121 ctcttttcct ctgcggctgt tacgtggttg ccctgggagc ccacaccggg gaggagagcg
181 tggctgacca tcacgaggct gaatattatg tggctgccgt gtatgagcat ccatccatcc
241 tgagtctgaa ccctctggct ctcatcagcc gccaagaggc cttggagctc atgaaccaga
301 accttgacat ctatgaacag caagtgatga ctgcagccca aaaggatgta cagattatag
361 tgtttccaga agatggcatt catggattca actttacaag aacatccatt tatccatttt
421 tggacttcat gccgtctccc caggtggtca ggtggaaccc atgcctggag cctcaccgct
481 tcaatgacac agaggtgctc cagcgcctga gttgtatggc catcagggga gatatgttct
541 tggtggccaa tcttgggaca aaggagcctt gtcatagcag tgacccaagg tgcccaaaag
601 atgggagata ccagttcaac acaaatgtcg tgttcagcaa taatggaacc cttgttgacc
661 gctaccgtaa acacaacctc tactttgagg cagcattcga tgttcctctt aaagtggatc
721 tcatcacctt tgataccccc tttgctggca ggtttggcat cttcacatgc tttgatatat
781 tgttctttga ccctgccatc agagtcctca gagactacaa ggtgaagcat gttgtgtacc
841 caactgcctg gatgaaccag ctcccactct tggcagcaat tgagattcag aaagcttttg
901 ctgttgcctt tggcatcaac gttctggcag ctaatgtcca ccacccagtt ctggggatga
961 caggaagtgg catacacacc cctctggagt ccttttggta ccatgacatg gaaaatccca
1021 aaagtcacct tataattgcc caggtggcca aaaatccagt gggtctcatt ggtgcagaga
1081 atgcaacagg tgaaacggac ccatcccata gtaagttttt aaaaattttg tcaggcgatc
1141 cgtactgtga gaaggatgct caggaagtcc actgtgatga ggccaccaag tggaacgtga
1201 atgctcctcc cacatttcac tctgagatga tgtatgacaa tttcaccctg gtccctgtct
1261 ggggaaagga aggctatctc cacgtctgtt ccaatggcct ctgctgttat ttactttacg
1321 agaggcccac cttatccaaa gagctgtatg ccctgggggt ctttgatggg cttcacacag
1381 tacatggcac ttactacatc caagtgtgtg ccctggtcag gtgtgggggt cttggcttcg
1441 acacctgcgg acaggaaatc acagaggcca cggggatatt tgagtttcac ctgtggggca
1501 acttcagtac ttcctatatc tttcctttgt ttctgacctc agggatgacc ctagaagtcc
1561 ctgaccagct tggctgggag aatgaccact atttcctgag gaaaagtagg ctgtcctctg
1621 ggctggtgac ggcggctctc tatgggcgct tgtatgagag ggactaggaa aagtgtgtgg
1681 tctgtggggc ggactctggc catcatgttg acagccttgc acttccacag gctacaagcc
1741 ctgggaccat ctttctgcct taagggcagg agcccacttc tgtggcacca gattccaccc
1801 tgggaactgt ggaaaaagta ggagaggcag attccctcag tgtcttcctc ttaaacctca
1861 atcatcgaga cattaggggg tattttctgt tcacatttat ctttttcaag ccacatcttc
1921 ctctaacaaa tctctcagta tgcgattggt ctcaagctaa aacaaaaata aatgtcagtt
1981 tatattttac acatccaaaa aaaaaaaaaa aaaaaa
//