LOCUS AH000843 4746 bp DNA linear HUM 24-JAN-2017
DEFINITION Homo sapiens acyl-CoA oxidase gene, complete cds, alternatively
spliced.
ACCESSION AH000843 U03254 U03255 U03256 U03257 U03258 U03259 U03260 U03261
U03262 U03263 U03264 U03265 U03266 U03267 U03268
VERSION AH000843.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4746)
AUTHORS Varanasi,U., Chu,R., Chu,S., Espinosa,R., LeBeau,M.M. and
Reddy,J.K.
TITLE Isolation of the human peroxisomal acyl-CoA oxidase gene:
organization, promoter analysis, and chromosomal localization
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91 (8), 3107-3111 (1994)
PUBMED 8159712
REFERENCE 2 (bases 1 to 4746)
AUTHORS Reddy,J.K.
TITLE Direct Submission
JOURNAL Submitted (04-NOV-1993) Reddy J.K., Northwestern University Medical
School, Pathology, 303 E. Chicago Ave, Chicago, IL 60611-3008, USA
COMMENT On or before Jan 24, 2017 this sequence version replaced U03254.1,
U03255.1, U03256.1, U03257.1, U03258.1, U03259.1, U03260.1,
U03261.1, U03262.1, U03263.1, U03264.1, U03265.1, U03266.1,
U03267.1, U03268.1, AH000843.1.
FEATURES Location/Qualifiers
source 1..4746
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/map="17q25.1"
/sex="male"
/cell_line="DMPC-HFF#1"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company P1"
CDS join(492..600,719..878,1007..1167,1583..1690,1823..1942,
2075..2190,2316..2485,2604..2766,2896..3086,3209..3388,
3510..3615,3739..3882,4006..4212,4340..4387)
/note="alternatively spliced with exon 3I"
/codon_start=1
/product="acyl-CoA oxidase"
/protein_id="AAA19113.1"
/translation="MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDP
DFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKKLHLVNFVEPVGL
NYSMFIPTLLNQGTTAQKEKWLLSSKGLQIIGTYAQTEMGHGTHLRGLETTATYDPET
QEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIRENRTHKPL
PGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGPYVKPLSNKLTYG
TMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPL
LATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEAC
RMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCG
MVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIH
RKSKEVAWNLTSVDLVRASEAHLHYGLVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYG
ISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRY
DGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL"
CDS join(492..600,719..878,1297..1457,1583..1690,1823..1942,
2075..2190,2316..2485,2604..2766,2896..3086,3209..3388,
3510..3615,3739..3882,4006..4212,4340..4387)
/note="alternatively spliced with exon 3II"
/codon_start=1
/product="acyl-CoA oxidase"
/protein_id="AAA19114.1"
/translation="MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDP
DFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKNFVHRGRPEPLDL
HLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPET
QEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIRENRTHKPL
PGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGPYVKPLSNKLTYG
TMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPL
LATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEAC
RMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCG
MVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIH
RKSKEVAWNLTSVDLVRASEAHLHYGLVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYG
ISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRY
DGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL"
exon 492..600
/product="acyl-CoA oxidase"
/number=1
gap 609..708
/estimated_length=unknown
exon 719..878
/number=2
gap 894..993
/estimated_length=unknown
exon 1007..1167
/number=3I
gap 1183..1282
/estimated_length=unknown
exon 1297..1457
/number=3II
gap 1470..1569
/estimated_length=unknown
exon 1583..1690
/number=4
gap 1707..1806
/estimated_length=unknown
exon 1823..1942
/number=5
gap 1957..2056
/estimated_length=unknown
exon 2075..2190
/number=6
gap 2204..2303
/estimated_length=unknown
exon 2316..2485
/number=7
gap 2496..2595
/estimated_length=unknown
exon 2604..2766
/number=8
gap 2780..2879
/estimated_length=unknown
exon 2896..3084
/number=9
gap 3101..3200
/estimated_length=unknown
exon 3209..3388
/number=10
gap 3398..3497
/estimated_length=unknown
exon 3510..3615
/number=11
gap 3627..3726
/estimated_length=unknown
exon 3739..3882
/number=12
gap 3894..3993
/estimated_length=unknown
exon 4006..4212
/number=13
gap 4231..4330
/estimated_length=unknown
exon 4340..4387
/number=14
BASE COUNT 825 a 843 c 856 g 822 t
ORIGIN
1 aatcacactc ctcagatcct cgttgataca cacagacccc cttcccaagc cccagccaac
61 ctgttctaaa tacgatcggt cctcggattt cttcttccgc ctcgacgtgg tcacgtgggg
121 gaaggaggcg ggaatacaaa gtgctttatt ttcccactcc ccggaccgca gcagggcagt
181 ttcttgactt cggagacccc tttccgagga tcagctcggg agcctccctg gcccaggagc
241 aggggatata gatctgcccg cgaccgcacc agccacgacg cggacatcgc cccctctgtc
301 tgggcgctgt actcacgcgc caaagggcac ggagaaagaa ggggcgggcg gggcgggccg
361 ggcgagcgga gagcggggac ttgcgccgtc ctgaggctgc ctcctagggt ccggccggcg
421 ctggagctgc ggatttagat tgtcactgca ccctcggtcg tgcgttactt cgctgccagc
481 tggtcgtcgc gatgaacccg gacctgcgca gggagcggga ttccgccagc ttcaacccgg
541 agctgcttac acacatcctg gacggcagcc ccgagaaaac gcgccgccgc cgagagatcg
601 gtgagggcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnncc ccctttagag
721 aacatgatcc tgaacgaccc agacttccag catgaggact tgaacttcct cactcgcagc
781 cagcgttatg aggtggctgt caggaaaagt gccatcatgg tgaagaagat gagggagttt
841 ggcatcgctg accctgatga aattatgtgg tttaaaaagt aggtatgcct tagnnnnnnn
901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnttctctt ctgtagacta catttggtca
1021 attttgtgga acctgtgggc ctcaattact ccatgtttat tcctaccttg ctgaatcagg
1081 gcaccactgc tcagaaagag aaatggctgc tttcatccaa aggactccag ataattggca
1141 cctacgccca gacggaaatg ggccacggtt agtccacatt gannnnnnnn nnnnnnnnnn
1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1261 nnnnnnnnnn nnnnnnnnnn nnatatttcc tcgaagtttt gtgcaccgag ggcggcctga
1321 gcctctggat cttcacttgg gcatgttcct gcccaccttg cttcaccagg caactgcgga
1381 gcagcaggag cgcttcttca tgcccgcctg gaacttggag atcattggca cttatgccca
1441 gacagagatg ggtcatggta tggagtatcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1561 nnnnnnnnnt ttatctcctt aggaactcac cttcgaggct tggaaaccac agccacgtat
1621 gaccctgaaa cccaggagtt cattctcaac agtcctactg tgacctccat taaatggtgg
1681 cctggtgggc gtaagtgaat ttttcannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1801 nnnnnngtca cttgatatta agttggaaag acttcaaatc atgcaatagt tcttgcccag
1861 ctcatcacta agggaaaatg ctatggatta catgccttta tcgtacctat tcgtgaaaat
1921 cggacccata agcctttgcc aggtaaagaa actgtannnn nnnnnnnnnn nnnnnnnnnn
1981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2041 nnnnnnnnnn nnnnnntcct ttcatctgtg gtaggaatta ccgttggtga catcggcccc
2101 aaatttggtt atgatgagat agacaatggc tacctcaaaa tggacaacca tcgtattccc
2161 agagaaaaca tgctgatgaa gtatgcccag gtatgttttg atannnnnnn nnnnnnnnnn
2221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2281 nnnnnnnnnn nnnnnnnnnn nnnttcttct tccaggtgaa gcctgatgga ccatacgtga
2341 aaccgctgag taacaagctg acttacggga ccatggtgtt tgtcaggtcc ttccttgtgg
2401 gagaagctgc tcgggctctg tctaaggcgt gcaccattgc catccgatac agcgctgtga
2461 ggcaccagtc tgaaatcaag ccagggtaag gatagnnnnn nnnnnnnnnn nnnnnnnnnn
2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2581 nnnnnnnnnn nnnnnctacg tagtgaacca gaaccacaga ttttggattt tcaaacccag
2641 cagtataaac tctttccact cctggccact gcctatgcct tccagtttgt gggcgcatac
2701 atgaaggaga cctatcaccg gattaacgaa ggcattggtc aaggggacct gagtgaactg
2761 cctgaggtat cagtttgggn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng
2881 tgcttgtcct ctcagcttca tgccctcacc gctggactga aggctttcac ctcctggact
2941 gcaaacactg gcattgaagc atgtcggatg gcttgtggtg ggcatggcta ttctcattgc
3001 agtggtcttc caaatattta tgtcaatttc accccaagct gtacctttga gggagaaaac
3061 actgtcatga tgctccagac ggctaggtga gagtcaaatc nnnnnnnnnn nnnnnnnnnn
3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3181 nnnnnnnnnn nnnnnnnnnn tcttttaggt tcctgatgaa aagttatgat caggtgcact
3241 caggaaagtt ggtgtgtggc atggtgtcct atttgaacga cctgcccagt cagcgcatcc
3301 agccacagca ggtagcagtc tggccaacca tggtggatat caacagcccc gaaagcctaa
3361 ccgaagcata taaactccgt gcagccaggt gagctctnnn nnnnnnnnnn nnnnnnnnnn
3421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3481 nnnnnnnnnn nnnnnnnatg tcttaacaga ttagtagaaa ttgctgcaaa aaaccttcaa
3541 aaagaagtga ttcacagaaa aagcaaggag gtagcttgga acctaacttc tgttgacctt
3601 gttcgagcaa gtgaggtcag tggtagnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3721 nnnnnntttt aatcttaggc acatttgcac tatgggttag ttaagctctt ttcagaaaaa
3781 ctcctcaaaa ttcaagataa agccattcaa gctgtcttaa ggagtttatg tctgctgtat
3841 tctctgtatg gaatcagtca gaacgcgggg gatttccttc aggtcagtat tttnnnnnnn
3901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntgtctct tttaggggag catcatgaca
4021 gagcctcaga ttacacaagt aaaccagcgt gtaaaggagt tactcactct gattcgctca
4081 gatgctgttg ctttggttga tgcatttgat tttcaggatg tgacacttgg ctctgtgctt
4141 ggccgctatg atgggaatgt gtatgaaaac ttgtttgagt gggctaagaa ctccccactg
4201 aacaaagcag aggtaaaaat ccagtgtctc nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4321 nnnnnnnnnn tccccacagg tccacgaatc ttacaagcac ctgaagtcac tgcagtccaa
4381 gctctgaagt gtcacaagga caagtttaat ctgcttcaga aagcgcctgt gtgcaactca
4441 aattttgtgg aatctttttc gaattcacga ggaagtaaac cagtggcacc catgtgacat
4501 aggcagcagc tgggcctcgg gagaccagca tgcctaggct gctccactcc caaaccagag
4561 tgtcccagag gcatgacagg agcctatggt accttcagag gaaaacctcc tgttctgatg
4621 cccagagctg ctgggatagg cagagtactt cttggaggga atggcacccc ctgcgagaga
4681 cgaaagcaag agtctagggc ctgagtctct cctggccaag atctctccct atatagcatg
4741 ggcccg
//