LOCUS U01147 5265 bp mRNA linear HUM 03-FEB-1994
DEFINITION Human guanine nucleotide regulatory protein (ABR) mRNA, complete
cds.
ACCESSION U01147
VERSION U01147.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Tan,E.C., Leung,T., Manser,E. and Lim,L.
TITLE The human active breakpoint cluster region-related gene encodes a
brain protein with homology to guanine nucleotide exchange proteins
and GTPase-activating proteins
JOURNAL J. Biol. Chem. 268 (36), 27291-27298 (1993)
PUBMED 8262969
REFERENCE 2 (bases 1 to 5265)
AUTHORS Tan,E.
TITLE Direct Submission
JOURNAL Submitted (31-AUG-1993) Tan E., Institute of Molecular and Cell
Biology, Kent Ridge, Singapore, Singapore, 0511
FEATURES Location/Qualifiers
source 1..5265
/db_xref="H-InvDB:HIT000217416"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="17p13.3"
/clone="ABR"
/sex="female"
/tissue_type="brain"
/clone_lib="hippocampal cDNA"
/dev_stage="infant"
gene 1..5265
/gene="ABR"
mRNA 1..5265
/gene="ABR"
CDS 111..2690
/gene="ABR"
/function="GTPase activating protein"
/standard_name="GAP"
/codon_start=1
/product="guanine nucleotide regulatory protein"
/protein_id="AAC50063.1"
/translation="MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGS
ETMPYIDESPTMSPQLSARSQGRGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLAS
EEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPK
VQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVK
GPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQN
FLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLK
KTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQ
KEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHV
IVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLR
ILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSM
KFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY
RISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPA
FMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLAT
VFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFS
TDV"
polyA_site 5242
/gene="ABR"
BASE COUNT 1202 a 1548 c 1454 g 1061 t
ORIGIN
1 ctcgcccctc cgcgctcgca acttcggcct cccccggctc ccgcccgccc tccctccttt
61 gttgcgcgat gagggtcggg tttcggatct gaccgagccg ccgccgcggg atggagccgc
121 tcagccaccg gggcctgccg cgcctgtcct ggatcgacac cctctacagc aacttcagct
181 acgggacgga cgagtacgac ggagagggga atgaggagca gaaggggccc ccggagggct
241 cagagaccat gccgtacatc gatgagtcgc ccaccatgtc cccgcagctc agcgcccgca
301 gccagggccg gggggatggc gtctccccga ctccacctga gggactggct cctggggtgg
361 aagcagggaa aggcctggag atgaggaagc tggttctctc ggggttcttg gccagcgaag
421 agatctacat taaccagctg gaagccctgt tgctgcccat gaaacccctg aaggccaccg
481 ccaccacctc ccagcccgtg ctcaccatcc agcagatcga gaccatcttc tacaagatcc
541 aggacatcta tgagatccac aaggagttct atgacaacct gtgccccaag gtgcaacagt
601 gggacagcca ggtcaccatg ggccacctct tccagaagct ggccagccag ctcggtgtgt
661 acaaagcgtt tgtcgataac tataaagtcg ctctggagac agctgagaag tgcagccagt
721 ccaacaacca gttccagaag atctcagagg aactcaaagt gaaaggtccc aaggactcca
781 aggacagcca cacgtctgtc accatggaag ctctgctcta caagcccatt gaccgggtca
841 ctcggagcac cctagtccta cacgacctgc tgaagcacac acctgtggac caccccgact
901 acccgctgct gcaggatgcc ctccgcatct cccagaactt cctgtccagc atcaacgagg
961 acatcgaccc ccgccggact gcagtgacaa cgcccaaggg ggagacgcga cagctggtga
1021 aggacggctt cctggtggaa gtgtcagaga gctcccggaa gctgcggcac gtcttcctct
1081 ttacagatgt cctactgtgt gccaagctga agaagacctc tgcagggaag caccagcagt
1141 atgactgtaa gtggtacatc cccctggccg acctggtgtt tccatccccc gaggaatctg
1201 aggccagccc ccaggtgcac cccttcccag accatgagct ggaggacatg aagatgaaga
1261 tctctgccct caagagtgaa atccagaagg agaaagccaa caaaggccag agccgtgcca
1321 tcgagcgcct gaagaagaag atgtttgaga atgagttcct gctgctgctc aactccccca
1381 caatcccgtt caggatccac aatcggaatg gaaagagtta cctgttccta ctgtcctcgg
1441 actacgagag gtcagagtgg agagaagcaa ttcagaaact acagaagaag gatctccagg
1501 cctttgtcct gagctcagtg gagctccagg tgctcacagg atcctgtttc aagcttagga
1561 ctgtacacaa cattcctgtc accagcaata aagacgacga tgagtctcca ggactctatg
1621 gcttccttca tgtcatcgtc cactctgcca agggatttaa gcaatcagcc aacctgtact
1681 gtaccctgga ggtggattcc ttcggctatt ttgtcagcaa agccaaaacc agggtgttcc
1741 gggacacagc ggagcccaag tgggatgagg agtttgagat cgagctggag ggctcccagt
1801 ccctgaggat cctgtgctat gagaagtgct atgacaagac caaggtcaac aaggacaaca
1861 atgagatcgt ggacaagatc atgggcaaag gacagatcca gctggaccca caaaccgtgg
1921 agaccaagaa ctggcacacg gacgtgattg agatgaacgg gatcaaagtg gaattttcca
1981 tgaaattcac cagccgagat atgagcctga agaggacccc gtccaaaaag cagaccggcg
2041 tcttcggtgt gaagatcagc gtggtgacga agcgggagcg ctccaaggtg ccctacatcg
2101 tccggcagtg tgtggaggag gtggagaaga ggggtatcga ggaggttggc atctacagga
2161 tatcgggcgt ggccacggac atccaggcgc tcaaggccgt cttcgatgcc aataacaagg
2221 acatcctgct gatgctgagt gacatggaca tcaacgccat cgccgggacg ctcaagctgt
2281 acttccggga actgcccgag ccgctcctca cggaccgact ctacccagcc ttcatggagg
2341 gcatcgccct gtcagaccct gctgccaagg aaaactgcat gatgcacctg ctccgctccc
2401 tgcccgaccc caacctcatc accttcctct tcctgctgga acacttgaaa agggttgccg
2461 agaaggagcc catcaacaaa atgtcacttc acaacctggc taccgtgttt ggacccacgt
2521 tactgagacc ctcagaagtg gagagcaaag cacacctcac ctcggctgcg gacatctggt
2581 cccatgacgt catggcgcag gtccaggtcc tcctctacta cctgcagcac ccccccattt
2641 ccttcgcaga actcaagcgg aacacactgt acttctccac cgacgtgtag cccgaggcag
2701 ggtggctgcg ggcgggtggt ggaaccagcc cctccagcct ggggtccaac tcagacttga
2761 aagactgcaa tagaaaactc ccaaacccag cactccagac tcgagggaag ccagcttcca
2821 agaactggaa tgcgtacgtc ttttgtgcca ccttgtacaa agccggctgc ccagccccag
2881 cctcaccacc gcatcccacc tcctgccctc catacctcta gttgtgtctg atgctccgtg
2941 ctgttcggga attgttttat gtacacttgt caggcagaaa aggtagtgac cggcccggcg
3001 tgggcacaca gacagcccgc tttgttcttt catttcctcc agcactttct ttccgcctga
3061 gtccagccca aggcctttta ttttgcgctg tgtaactgct gccagcttct ctcttggccc
3121 tgctcccaga tggcggtctc ctggcagcct cccctcagtc ttcctccacc cgcctcttcc
3181 ttcccagcct gcctgcatgc atgtgcaccc ttggtcttcg ctccatcgcc ttgaaagctc
3241 tgaagaggcc ctgggttgtc gcggcagcag tggtctgttt gatgctgccg tttgccgctg
3301 ccggcccctc ctcagactcc gcctttggga gcacacctgc tttgccttgc tgcctgtgca
3361 aatgttggac aagcagacac actcacactc gtccccagct tagcacagag ctggagcgcc
3421 catttctgga attttccgtt tgggaatctc cacttctggg gtttacctgt tcggcctcct
3481 gcctatcagt gaggcatctc tgactgttcc ttctactgct tttcagttcc cttccctgct
3541 gttctatttc ctttgagtgt aaagactcac aggtgacctg ctatcgagat agccagaggg
3601 tcaggagaga atgggggagg aggcggtcag gctgctgagg aaacaccaca ggctgaacgg
3661 gggaggaatg cacatgccac gctgggtgtc ccgggtcgcg gggaggcagc tcagctctta
3721 ggagcaagtt gtgggggctt ttcaagaggg gccaggcttc ctggagggtg actgatgtgg
3781 ccgaagcagg tgtccaggca ggtaggctgc agccaggagc tccctggcac cgcaggacct
3841 cgtggtactc ttgccttaga ttttacacac actccacagc caagcactgc cacggtcctc
3901 caggacctgg gaagcaaagg cacaggccca cggtggccag ccattgtggt gccgccccag
3961 cttctggata cagccttttg ggtaaacact gggaactcca gaagttgtgg ggagagtggg
4021 gaatcagaca gccgcctcta ggggctgggt tctgctgggg cctccttgtt ggtgctgtag
4081 gcacccgcca ggagcaggga cccgacttgc agacgcattg cccggtacta ggaaggagtg
4141 aggtgtgttc ccaccgtaca cttcccacac gagctgcggc tgccagcctc gggccatcag
4201 cctaggagag cagatgcagc tccaggggct cgacttatag ccagttacag ctccccggct
4261 cttctgtgtg gcagagcgtc gtttccgggc cctcagggct ggggagctca gttcccattg
4321 cttgtgctca gggctgagtc ttaaagaagg gtttgccggc cctaacgctg cagccgtgct
4381 gagaggccct ttttgagcct gtttactcct gtggccttgg gcagaacagt aaatactctg
4441 tgcacggagg aaagacatgc ccaagaggaa ggaagtactg accatcggct gcctgtgagc
4501 agcttagcaa ggagcccttg ctccctggga aaggcggtga acttgagtct aaagatgcag
4561 tgcctggccc ttcctaaggt ccctgcctgg catccgagtg tcggtgtgtg gcacagaagg
4621 ctcctgcttg cttccaaagt gatggacagg aaggggcaga gtgagtcacg gcccagactg
4681 cgaccttcac gtctcagcct cagggagccc cacagcccca agctcgctga ggcaacgtga
4741 gaacaggcta tgggaaggct gcaaaggctg agaaatgcaa aggctcatat ttataaatcc
4801 cacccccaga gtggggaggg tcaggtgcca gacctggact aaactgcacc aaggaaacac
4861 ccagcagggt ctcctgtgag ccggggacca tgcagcccga aacctccagt cactgcgccc
4921 ggcaggagtc aggagccagg gactgtgcag cctggaacct ccagtcactg tgccagcagg
4981 gtggctgtgc ccagcaggag tcaggctaag aaacgccagg tctgcctgtt cttgctgggc
5041 aatggctgat ggctgccagt ttctgctgat acacaggtag gatgggaccc ttcatgaata
5101 tctgacttta ataagttggt aaggatatat ttttttgtct atgttctgtt tcaacttatg
5161 tagattatta taaattgatg taaaccacgt gagaggaaaa tgttaataaa aaatgcaaag
5221 ccccatcatt tgcacaaaac tcaaaaaaaa aaaaaaaaaa aaaaa
//