LOCUS U01104 2616 bp mRNA linear HUM 06-JUN-2008
DEFINITION Human glucagon-like peptide-1 receptor mRNA, complete cds.
ACCESSION U01104
VERSION U01104.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2616)
AUTHORS Thorens,B., Porret,A., Buhler,L., Deng,S.P., Morel,P. and
Widmann,C.
TITLE Cloning and functional expression of the human islet GLP-1
receptor. Demonstration that exendin-4 is an agonist and
exendin-(9-39) an antagonist of the receptor
JOURNAL Diabetes 42 (11), 1678-1682 (1993)
PUBMED 8405712
REFERENCE 2 (bases 1 to 2616)
AUTHORS Thorens,B.
TITLE Direct Submission
JOURNAL Submitted (30-AUG-1993) Bernard Thorens, Institute of Pharmacology
and Toxicology, University of Lausanne, 27, Bugnon, Lausanne, 1005,
Switzerland
FEATURES Location/Qualifiers
source 1..2616
/db_xref="H-InvDB:HIT000217413"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="Langerhans islets"
/dev_stage="adult"
CDS 43..1434
/codon_start=1
/product="glucagon-like peptide-1 receptor"
/protein_id="AAA03614.1"
/translation="MAGAPGPLRLAVLLLGMVGRAGPRPQGATVSLWETVQKWREYRR
QCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYR
FCTAEGLWLQKDNSSLPWRDLSECEESKRGERSWGEEQLLFLYIIYTVAYALSFSALV
IASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLL
SYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQWIFRLYVSIGWGV
PLLFVVPWGIVKILYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSK
LKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTS
FQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAG
SSMYTATCQASCS"
repeat_region 1490..1645
/satellite="satellite"
repeat_region 1490..1491
BASE COUNT 538 a 767 c 706 g 605 t
ORIGIN
1 ttccgcaggt ggcagcgatg gcccagtcct gaactccccg ccatggccgg cgcccccggc
61 ccgctgcgcc ttgccgtgct gctgctcggg atggtgggca gggccggccc ccgcccccag
121 ggtgccactg tgtccctctg ggagacggtg cagaaatggc gagaataccg acgccagtgc
181 cagcgctccc tgactgagga tccacctcct gccacagact tgttctgcaa ccggaccttc
241 gatgaatacg cctgctggcc agatggggag ccaggctcgt tcgtgaatgt cagctgcccc
301 tggtacctgc cctgggccag cagtgtgccg cagggccacg tgtaccggtt ctgcacagct
361 gaaggcctct ggctgcagaa ggacaactcc agcctgccct ggagggactt gtcggagtgc
421 gaggagtcca agcgagggga gagaagctgg ggggaggagc agctcctgtt cctctacatc
481 atctacacgg tggcgtacgc actctccttc tctgctctgg ttatcgcctc tgcgatcctc
541 ctcggcttca gacacctgca ctgcaccagg aactacatcc acctgaacct gtttgcatcc
601 ttcatcctgc gagcattgtc cgtcttcatc aaggacgcag ccctgaagtg gatgtatagc
661 acagccgccc agcagcacca gtgggatggg ctcctctcct accaggactc tctgagctgc
721 cgcctggtgt ttctgctcat gcagtactgt gtggcggcca attactactg gctcttggtg
781 gagggcgtgt acctgtacac actgctggcc ttctcggtct tctctgagca atggatcttc
841 aggctctacg tgagcatagg ctggggtgtt cccctgctgt ttgttgtccc ctggggcatt
901 gtcaagatcc tctatgagga cgagggctgc tggaccagga actccaacat gaactactgg
961 ctcattatcc ggctgcccat tctctttgcc attggggtga acttcctcat ctttgttcgg
1021 gtcatctgca tcgtggtatc caaactgaag gccaatctca tgtgcaagac agacatcaaa
1081 tgcagacttg ccaagtccac gctgacactc atccccctgc tggggactca tgaggtcatc
1141 tttgcctttg tgatggacga gcacgcccgg gggaccctgc gcttcatcaa gctgtttaca
1201 gagctctcct tcacctcctt ccaggggctg atggtggcca tcttatactg ctttgtcaac
1261 aatgaggtcc agctggaatt tcggaagagc tgggagcgct ggcggcttga gcacttgcac
1321 atccagaggg acagcagcat gaagcccctc aagtgtccca ccagcagcct gagcagtgga
1381 gccacggcgg gcagcagcat gtacacagcc acttgccagg cctcctgcag ctgagactcc
1441 agcgcctgcc ctccctgggg tccttgctgc aggccgggtg gcaatccagg tgggagagac
1501 actcccaggg acaagggaag gaagggacac acacacacac acacacacac acacacacac
1561 acatacatcc tgctttccct ccccaaaccc atcagacagg taaatgggca gtgcctcctg
1621 ggaccatgga cacattttct cctaggagaa gcagcctcct aatttgatca cagtggcgag
1681 aggagaggaa aaacgatcgc tgtgaaaatg aggaggattg cttcttgtga aaccacaggc
1741 ccttggggtt cccccagaca gagccgcaaa tcaaccccag actcaaactc aaggtcaacg
1801 gcttattagt gaaactgggg cttgcaagag gaggtggttc tgaaagtggc tcttctaacc
1861 tcagccaaac acagagcggg agtgacggga gcctcctctg cttgcatcac ttggggtcac
1921 caccctcccc tgtcttctct caaagggaag ctgtttgtgt gtctgggttg cttatttccc
1981 tcatcttgcc ccctcatctc actgcccagt ttctttttga gggcttgttg gccactgcca
2041 gcagctgttt ctggaaatgg ctgtaggtgg tgttgagaaa gaatgagcat tgagacacgg
2101 tgctcgcttc tcctccaggt atttgagttg ttttggtgcc tgcctctgcc atgcccagag
2161 aatcagggca ggcttgccac cggggaaccc agccctgggg tatgagctgc caagtctatt
2221 ttaaagacgc tcaagaatcc tctggggttc atctagggac acgttaggaa tgtccagact
2281 gtgggtgtag gttacctgcc acttccagga cgcagagggc caagagagac attgcctcca
2341 cctctcctga atacttatct gtgaccacac gctgtctctt gagatttgga tacactctct
2401 agctttaggg gaccatgaag agactctctt aggaaaccaa tagtccccat cagcaccatg
2461 gaggcaggct ccccctgcct ttgaaattcc cccacttggg agctgatata cttcactcac
2521 ttttctttat tgctgtgata gtctgtgtgc acaatgggca attctgactt ctcccatcta
2581 gtggaaatga gcgaaatcat ggttgtagtg atcttg
//