LOCUS HSU00803 2863 bp mRNA linear HUM 25-MAY-1994
DEFINITION Human SRC-like tyrosine kinase (FRK) mRNA, complete cds.
ACCESSION U00803
VERSION U00803.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2863)
AUTHORS Lee,J., Wang,Z., Luoh,S.M., Wood,W.I. and Scadden,D.T.
TITLE Cloning of FRK, a novel human intracellular SRC-like tyrosine
kinase-encoding gene
JOURNAL Gene 138 (1-2), 247-251 (1994)
PUBMED 7510261
REFERENCE 2 (bases 1 to 2863)
AUTHORS Scadden,D.T.
TITLE Direct Submission
JOURNAL Submitted (17-AUG-1993) D.T. Scadden, New England Deaconess
Hospital, Hematology/Oncology, 185 Pilgrim Road, Boston, MA, USA,
02215
FEATURES Location/Qualifiers
source 1..2863
/db_xref="H-InvDB:HIT000217382"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="BL979"
/cell_type="lymphocytehepatoma"
/tissue_type="lymphoid"
gene 1..2863
/gene="FRK"
CDS 448..1965
/gene="FRK"
/codon_start=1
/product="SRC-like tyrosine kinase"
/protein_id="AAA18284.1"
/translation="MSNICQRLWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHG
HYFVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPS
NYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA
VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFD
LSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLR
EAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDM
AAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE
IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY
RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFETDSSYSDANNFIR"
BASE COUNT 895 a 550 c 624 g 794 t
ORIGIN
1 cctggcgaaa gcaagacgtg gaggttttac caggggttag tagcttcctc ttgctaactt
61 tttattggga caaaaggcaa gatggcacca ttctgttctc agatatttgt ctaaataaag
121 cccttttaat tttattttat ttttgttgtg ggattcttaa gcagataaga agaaaagaca
181 ccttcctagt gagcagctgc ccagctcctg ctcagttttg cctcggggta gcacctccag
241 ccacagaaag caagccggta agtctctcca ggtaggactt gctgcaaccc agctgctgga
301 ctgatctgaa acgggacttt gcatactctc cgaagtatgg tgagttggtg ctgacttcaa
361 agttgcctgg tgaaggaaga taaggtggat cgcagagact aaggggagag ggagaagccc
421 tgctcctctt ctccccacca aggcacaatg agcaacatct gtcagaggct ctgggagtac
481 ctagaaccct atctcccctg tttgtccacg gaggcagaca agtcaaccgt gattgaaaat
541 ccaggggccc tttgctctcc ccagtcacag aggcatggcc actactttgt ggctttgttt
601 gattaccagg ctcggactgc tgaggacttg agcttccgag caggtgacaa acttcaagtt
661 ctggacactt tgcatgaggg ctggtggttt gccagacact tggagaaaag acgagatggc
721 tccagtcagc aactacaagg ctatattcct tctaactacg tggctgagga cagaagccta
781 caggcagagc cgtggttctt tggagcaatc ggaagatcag atgcagagaa acaactatta
841 tattcagaaa acaagaccgg ttcctttcta atcagagaaa gtgaaagcca aaaaggagaa
901 ttctctcttt cagttttaga tggagcagtt gtaaaacact acagaattaa aagactggat
961 gaagggggat tttttctcac gcgaagaaga atcttttcaa cactgaacga atttgtgagc
1021 cactacacca agacaagtga cggcctgtgt gtcaagctgg ggaaaccatg cttaaagatc
1081 caggtcccag ctccatttga tttgtcgtat aaaaccgtgg accaatggga gatagaccgc
1141 aactccatac agcttctgaa gcgattggga tctggtcagt ttggcgaagt atgggaaggt
1201 ctgtggaaca ataccactcc agtagcagtg aaaacattaa aaccaggttc aatggatcca
1261 aatgacttcc tgagggaggc acagataatg aagaacctaa gacatccaaa gcttatccag
1321 ctttatgctg tttgcacttt agaagatcca atttatatta ttacagagtt gatgagacat
1381 ggaagtctgc aagaatatct ccaaaatgac actggatcaa aaatccatct gactcaacag
1441 gtagacatgg cggcacaggt tgcctctgga atggcctatc tggagtctcg gaactacatt
1501 cacagagatc tggctgccag aaatgtcctc gttggtgaac ataatatcta caaagtagca
1561 gattttggac ttgccagagt ttttaaggta gataatgaag acatctatga atctagacac
1621 gaaataaagc tgccggtgaa gtggactgcg cccgaagcca ttcgtagtaa taaattcagc
1681 attaagtccg atgtatggtc atttggaatc cttctttatg aaatcattac ttatggcaaa
1741 atgccttaca gtggtatgac aggtgcccag gtaatccaga tgttggctca aaactataga
1801 cttccgcaac catccaactg tccacagcaa ttttacaaca tcatgttgga gtgctggaat
1861 gcagagccta aggaacgacc tacatttgag acactgcgtt ggaaacttga agactatttt
1921 gaaacagact cttcatattc agatgcaaat aacttcataa gatgaacact ggagaagaat
1981 atcaaataat aaagtagcaa aacaaattca aataatccat tccaaaatac aatgttatca
2041 accaactgca caatcagttt atcctgacat attcaagtga taggataaag ttggccatgt
2101 attatgaaaa agattatttg tgcattttat tgactgggca acactgcagg acagtcaagg
2161 tgatatataa tttcctcact gcctggtaaa attaagcaca ctaaaccaag ttatttttct
2221 ttttaagaga tacttacatt tccatttatt gtttgaaatg tcgatcaaga gaatcaacag
2281 atgatagtcc aatttttact cagtgactgt tgtagcattt tcctgtttac tgattagagt
2341 ggttattcat tattcctcag attgctgaat cccatcaggc tgttattatg aaggaatttg
2401 attgctttgc tgcacagcag gacctgtgct ttgagatttt tttttctctt ttaaaatatc
2461 ctgtaactac aatgatggta aagccatgtt aaatgacttg attgtacttg gagtaattgc
2521 acattttttt ctatgcataa aaaaatgatg cagctgttga gaaaacgaag tctttttcat
2581 tttgcagaag gaaatgatgg aatttttctg tacttcagta tgtgtcaact gagagtcata
2641 tacattagtt ttaatctctt aatattgaga atcaggttgc aaaacggatg agttattatc
2701 tatggaaatg tgagaaatgt ctaatagccc ataaagtctg agaaataggt atcaaaatag
2761 tttaggaaaa tgagaggaga acagtagatt gctgtggcct agacttctga gtaattaata
2821 aagaaaaaga agtacccttt ggcctacaaa aaaaaaaaaa aaa
//