LOCUS U00672 3632 bp mRNA linear HUM 04-MAY-1994
DEFINITION Human interleukin-10 receptor mRNA, complete cds.
ACCESSION U00672
VERSION U00672.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3632)
AUTHORS Liu,Y., Wei,S.H., Ho,A.S., de Waal Malefyt,R. and Moore,K.W.
TITLE Expression cloning and characterization of a human IL-10 receptor
JOURNAL J. Immunol. 152 (4), 1821-1829 (1994)
PUBMED 8120391
REFERENCE 2 (bases 1 to 3632)
AUTHORS Moore,K.W.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-1993) Kevin W. Moore, Immunology, DNAX Research
Institute, 901 California Ave., Palo Alto, CA 94304, USA
FEATURES Location/Qualifiers
source 1..3632
/db_xref="H-InvDB:HIT000217377"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/clone="pSW8.1"
/cell_line="BJAB"
/cell_type="B lymphocyte"
/clone_lib="BJAB x pJFE14"
CDS 62..1798
/codon_start=1
/product="interleukin-10 receptor"
/protein_id="AAA17896.1"
/translation="MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILH
WTPIPNQSESTCYEVALLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRA
VDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESI
FSHFREYEIAIRKVPGNFTFTHKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMW
SKEECISLTRQYFTVTNVIIFFAFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPS
PFIFISQRPSPETQDTIHPLDEEAFLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQ
FLLPDPHPQADRTLGNGEPPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGPTWEQQVG
SNSRGQDDSGIDLVQNSEGRAGDTQGGSALGHHSPPEPEVPGEEDPAAVAFQGYLRQT
RCAEEKATKTGCLEEESPLTDGLGPKFGRCLVDEAGLHPPALAKGYLKQDPLEMTLAS
SGAPTGQWNQPTEEWSLLALSSCSDLGISDWSFAHDLAPLGCVAAPGGLLGSFNSDLV
TLPLISSLQSSE"
sig_peptide 62..124
mat_peptide 125..1795
/product="unnamed"
regulatory 3613..3618
/regulatory_class="polyA_signal_sequence"
BASE COUNT 804 a 1018 c 1003 g 807 t
ORIGIN
1 aaagagctgg aggcgcgcag gccggctccg ctccggcccc ggacgatgcg gcgcgcccag
61 gatgctgccg tgcctcgtag tgctgctggc ggcgctcctc agcctccgtc ttggctcaga
121 cgctcatggg acagagctgc ccagccctcc gtctgtgtgg tttgaagcag aatttttcca
181 ccacatcctc cactggacac ccatcccaaa tcagtctgaa agtacctgct atgaagtggc
241 gctcctgagg tatggaatag agtcctggaa ctccatctcc aactgtagcc agaccctgtc
301 ctatgacctt accgcagtga ccttggacct gtaccacagc aatggctacc gggccagagt
361 gcgggctgtg gacggcagcc ggcactccaa ctggaccgtc accaacaccc gcttctctgt
421 ggatgaagtg actctgacag ttggcagtgt gaacctagag atccacaatg gcttcatcct
481 cgggaagatt cagctaccca ggcccaagat ggcccccgcg aatgacacat atgaaagcat
541 cttcagtcac ttccgagagt atgagattgc cattcgcaag gtgccgggaa acttcacgtt
601 cacacacaag aaagtaaaac atgaaaactt cagcctccta acctctggag aagtgggaga
661 gttctgtgtc caggtgaaac catctgtcgc ttcccgaagt aacaagggga tgtggtctaa
721 agaggagtgc atctccctca ccaggcagta tttcaccgtg accaacgtca tcatcttctt
781 tgcctttgtc ctgctgctct ccggagccct cgcctactgc ctggccctcc agctgtatgt
841 gcggcgccga aagaagctac ccagtgtcct gctcttcaag aagcccagcc ccttcatctt
901 catcagccag cgtccctccc cagagaccca agacaccatc cacccgcttg atgaggaggc
961 ctttttgaag gtgtccccag agctgaagaa cttggacctg cacggcagca cagacagtgg
1021 ctttggcagc accaagccat ccctgcagac tgaagagccc cagttcctcc tccctgaccc
1081 tcacccccag gctgacagaa cgctgggaaa cggggagccc cctgtgctgg gggacagctg
1141 cagtagtggc agcagcaata gcacagacag cgggatctgc ctgcaggagc ccagcctgag
1201 ccccagcaca gggcccacct gggagcaaca ggtggggagc aacagcaggg gccaggatga
1261 cagtggcatt gacttagttc aaaactctga gggccgggct ggggacacac agggtggctc
1321 ggccttgggc caccacagtc ccccggagcc tgaggtgcct ggggaagaag acccagctgc
1381 tgtggcattc cagggttacc tgaggcagac cagatgtgct gaagagaagg caaccaagac
1441 aggctgcctg gaggaagaat cgcccttgac agatggcctt ggccccaaat tcgggagatg
1501 cctggttgat gaggcaggct tgcatccacc agccctggcc aagggctatt tgaaacagga
1561 tcctctagaa atgactctgg cttcctcagg ggccccaacg ggacagtgga accagcccac
1621 tgaggaatgg tcactcctgg ccttgagcag ctgcagtgac ctgggaatat ctgactggag
1681 ctttgcccat gaccttgccc ctctaggctg tgtggcagcc ccaggtggtc tcctgggcag
1741 ctttaactca gacctggtca ccctgcccct catctctagc ctgcagtcaa gtgagtgact
1801 cgggctgaga ggctgctttt gattttagcc atgcctgctc ctctgcctgg accaggagga
1861 gggccctggg gcagaagtta ggcacgaggc agtctgggca cttttctgca agtccactgg
1921 ggctggccca gccaggctgc agggctggtc agggtgtctg gggcaggagg aggccaactc
1981 actgaactag tgcagggtat gtgggtggca ctgacctgtt ctgttgactg gggccctgca
2041 gactctggca gagctgagaa gggcagggac cttctccctc ctaggaactc tttcctgtat
2101 cataaaggat tatttgctca ggggaaccat ggggctttct ggagttgtgg tgaggccacc
2161 aggctgaagt cagctcagac ccagacctcc ctgcttaggc cactcgagca tcagagcttc
2221 cagcaggagg aagggctgta ggaatggaag cttcagggcc ttgctgctgg ggtcattttt
2281 aggggaaaaa ggaggatatg atggtcacat ggggaacctc ccctcatcgg gcctctgggg
2341 caggaagctt gtcactggaa gatcttaagg tatatatttt ctggacactc aaacacatca
2401 taatggattc actgagggga gacaaaggga gccgagaccc tggatggggc ttccagctca
2461 gaacccatcc ctctggtggg tacctctggc acccatctgc aaatatctcc ctctctccaa
2521 caaatggagt agcatccccc tggggcactt gctgaggcca agccactcac atcctcactt
2581 tgctgcccca ccatcttgct gacaacttcc agagaagcca tggttttttg tattggtcat
2641 aactcagccc tttgggcggc ctctgggctt gggcaccagc tcatgccagc cccagagggt
2701 cagggttgga ggcctgtgct tgtgtttgct gctaatgtcc agctacagac ccagaggata
2761 agccactggg cactgggctg gggtccctgc cttgttggtg ttcagctgtg tgattttgga
2821 ctagccactt gtcagagggc ctcaatctcc catctgtgaa ataaggactc cacctttagg
2881 ggaccctcca tgtttgctgg gtattagcca agctggtcct gggagaatgc agatactgtc
2941 cgtggactac caagctggct tgtttcttat gccagaggct aacagatcca atgggagtcc
3001 atggtgtcat gccaagacag tatcagacac agccccagaa gggggcatta tgggccctgc
3061 ctccccatag gccatttgga ctctgccttc aaacaaaggc agttcagtcc acaggcatgg
3121 aagctgtgag gggacaggcc tgtgcgtgcc atccagagtc atctcagccc tgcctttctc
3181 tggagcattc tgaaaacaga tattctggcc cagggaatcc agccatgacc cccacccctc
3241 tgccaaagta ctcttaggtg ccagtctggt aactgaactc cctctggagg caggcttgag
3301 ggaggattcc tcagggttcc cttgaaagct ttatttattt attttgttca tttatttatt
3361 ggagaggcag cattgcacag tgaaagaatt ctggatatct caggagcccc gaaattctag
3421 ctctgacttt gctgtttcca gtggtatgac cttggagaag tcacttatcc tcttggagcc
3481 tcagtttcct catctgcaga ataatgactg acttgtctaa ttcataggga tgtgaggttc
3541 tgctgaggaa atgggtatga atgtgccttg aacacaaagc tctgtcaata agtgatacat
3601 gttttttatt ccaataaatt gtcaagacca ca
//