LOCUS S83176 3234 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens calcium-sensing receptor long isoform (CASR) mRNA,
partial cds.
ACCESSION S83176
VERSION S83176.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3234)
AUTHORS Freichel,M., Zink-Lorenz,A., Holloschi,A., Hafner,M., Flockerzi,V.
and Raue,F.
TITLE Expression of a calcium-sensing receptor in a human medullary
thyroid carcinoma cell line and its contribution to calcitonin
secretion
JOURNAL Endocrinology 137 (9), 3842-3848 (1996)
PUBMED 8756555
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 179653] from the original journal article.
COMMENT Compare X81086.
FEATURES Location/Qualifiers
source 1..3234
/db_xref="H-InvDB:HIT000217193"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="TT"
/tissue_type="medullary thyroid carcinoma"
gene 1..>3234
/gene="CASR"
CDS 1..>3234
/gene="CASR"
/codon_start=1
/product="calcium-sensing receptor long isoform"
/protein_id="AAB46873.1"
/translation="MAFYSCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGV
AAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCN
TVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLF
YIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDY
GRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDL
EPLIKEIVRRNITGKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFL
KKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFR
PLCTGDENISSVETPYIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCA
DIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEV
GYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECV
ECPDGEYSDETDASACNKCPDDFWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGI
FLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQP
AFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICV
IWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLP
ENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIAILAASFGLLACIFFNK
IYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSSSLGGSTGSTPSSSI
SSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLTLPQQQRSQQQPRCKQKVIFGSGT
VTFSLSFDEPQKNAMAHRNSTHQNSLEAQKSSDTLTRHQPLLPLQCGETDLDLTVQET
GLQGPVGGDQRPEVEDPEELSPALVVSSSQSFVISGGGSTVTENVVNS"
misc_feature join(1..185,493..769)
/gene="CASR"
/note="calcium-sensing receptor isoform b; CaSRb;
alternatively spliced"
BASE COUNT 740 a 930 c 828 g 736 t
ORIGIN
1 atggcatttt atagctgctg ctgggtcctc ttggcactca cctggcacac ctctgcctac
61 gggccagacc agcgagccca aaagaagggg gacattatcc ttggggggct ctttcctatt
121 cattttggag tagcagctaa agatcaagat ctcaaatcaa ggccggagtc tgtggaatgt
181 atcaggtata atttccgtgg gtttcgctgg ttacaggcta tgatatttgc catagaggag
241 ataaacagca gcccagccct tcttcccaac ttgacgctgg gatacaggat atttgacact
301 tgcaacaccg tttctaaggc cttggaagcc accctgagtt ttgttgctca aaacaaaatt
361 gattctttga accttgatga gttctgcaac tgctcagagc acattccctc tacgattgct
421 gtggtgggag caactggctc aggcgtctcc acggcagtgg caaatctgct ggggctcttc
481 tacattcccc aggtcagtta tgcctcctcc agcagactcc tcagcaacaa gaatcaattc
541 aagtctttcc tccgaaccat ccccaatgat gagcaccagg ccactgccat ggcagacatc
601 atcgagtatt tccgctggaa ctgggtgggc acaattgcag ctgatgacga ctatgggcgg
661 ccggggattg agaaattccg agaggaagct gaggaaaggg atatctgcat cgacttcagt
721 gaactcatct cccagtactc tgatgaggaa gagatccagc atgtggtaga ggtgattcaa
781 aattccacgg ccaaagtcat cgtggttttc tccagtggcc cagatcttga gcccctcatc
841 aaggagattg tccggcgcaa tatcacgggc aagatctggc tggccagcga ggcctgggcc
901 agctcctccc tgatcgccat gcctcagtac ttccacgtgg ttggcggcac cattggattc
961 gctctgaagg ctgggcagat cccaggcttc cgggaattcc tgaagaaggt ccatcccagg
1021 aagtctgtcc acaatggttt tgccaaggag ttttgggaag aaacatttaa ctgccacctc
1081 caagaaggtg caaaaggacc tttacctgtg gacacctttc tgagaggtca cgaagaaagt
1141 ggcgacaggt ttagcaacag ctcgacagcc ttccgacccc tctgtacagg ggatgagaac
1201 atcagcagtg tcgagacccc ttacatagat tacacgcatt tacggatatc ctacaatgtg
1261 tacttagcag tctactccat tgcccacgcc ttgcaagata tatatacctg cttacctggg
1321 agagggctct tcaccaatgg ctcctgtgca gacatcaaga aagttgaggc gtggcaggtc
1381 ctgaagcacc tacggcatct aaactttaca aacaatatgg gggagcaggt gacctttgat
1441 gagtgtggtg acctggtggg gaactattcc atcatcaact ggcacctctc cccagaggat
1501 ggctccatcg tgtttaagga agtcgggtat tacaacgtct atgccaagaa gggagaaaga
1561 ctcttcatca acgaggagaa aatcctgtgg agtgggttct ccagggaggt gcccttctcc
1621 aactgcagcc gagactgcct ggcagggacc aggaaaggga tcattgaggg ggagcccacc
1681 tgctgctttg agtgtgtgga gtgtcctgat ggggagtata gtgatgagac agatgccagt
1741 gcctgtaaca agtgcccaga tgacttctgg tccaatgaga accacacctc ctgcattgcc
1801 aaggagatcg agtttctgtc gtggacggag ccctttggga tcgcactcac cctctttgcc
1861 gtgctgggca ttttcctgac agcctttgtg ctgggtgtgt ttatcaagtt ccgcaacaca
1921 cccattgtca aggccaccaa ccgagagctc tcctacctcc tcctcttctc cctgctctgc
1981 tgcttctcca gctccctgtt cttcatcggg gagccccagg actggacgtg ccgcctgcgc
2041 cagccggcct ttggcatcag cttcgtgctc tgcatctcat gcatcctggt gaaaaccaac
2101 cgtgtcctcc tggtgtttga ggccaagatc cccaccagct tccaccgcaa gtggtggggg
2161 ctcaacctgc agttcctgct ggttttcctc tgcaccttca tgcagattgt catctgtgtg
2221 atctggctct acaccgcgcc cccctcaagc taccgcaacc aggagctgga ggatgagatc
2281 atcttcatca cgtgccacga gggctccctc atggccctgg gcttcctgat cggctacacc
2341 tgcctgctgg ctgccatctg cttcttcttt gccttcaagt cccggaagct gccggagaac
2401 ttcaatgaag ccaagttcat caccttcagc atgctcatct tcttcatcgt ctggatctcc
2461 ttcattccag cctatgccag cacctatggc aagtttgtct ctgccgtaga ggtgattgcc
2521 atcctggcag ccagctttgg cttgctggcg tgcatcttct tcaacaagat ctacatcatt
2581 ctcttcaagc catcccgcaa caccatcgag gaggtgcgtt gcagcaccgc agctcacgct
2641 ttcaaggtgg ctgcccgggc cacgctgcgc cgcagcaacg tctcccgcaa gcggtccagc
2701 agccttggag gctccacggg atccacccct tcctcctcca tcagcagcaa gagcaacagc
2761 gaagacccat tcccacagcc cgagaggcag aagcagcagc agccgctggc cctaacccag
2821 caagagcagc agcagcagcc cctgaccctc ccacagcagc aacgatctca gcagcagccc
2881 agatgcaagc agaaggtcat ctttggcagc ggcacggtca ccttctcact gagctttgat
2941 gagcctcaga agaacgccat ggcccacagg aattctacgc accagaactc cctggaggcc
3001 cagaaaagca gcgatacgct gacccgacac cagccattac tcccgctgca gtgcggggaa
3061 acggacttag atctgaccgt ccaggaaaca ggtctgcaag gacctgtggg tggagaccag
3121 cggccagagg tggaggaccc tgaagagttg tccccagcac ttgtagtgtc cagttcacag
3181 agctttgtca tcagtggtgg aggcagcact gttacagaaa acgtagtgaa ttca
//