LOCUS S78271 5190 bp mRNA linear HUM 27-SEP-1995
DEFINITION SB1.8/DXS423E=mitosis-specific chromosome segregation protein SMC1
homolog [human, HT1080 and M426 fibroblast cell lines, mRNA, 5190
nt].
ACCESSION S78271
VERSION S78271.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5190)
AUTHORS Rocques,P.J., Clark,J., Ball,S., Crew,J., Gill,S.,
Christodoulou,Z., Borts,R.H., Louis,E.J., Davies,K.E. and
Cooper,C.S.
TITLE The human SB1.8 gene (DXS423E) encodes a putative chromosome
segregation protein conserved in lower eukaryotes and prokaryotes
JOURNAL Hum. Mol. Genet. 4 (2), 243-249 (1995)
PUBMED 7757074
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 167455] from the original journal article.
FEATURES Location/Qualifiers
source 1..5190
/db_xref="H-InvDB:HIT000216786"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..5190
/gene="SB1.8/DXS423E"
/note="mitosis-specific chromosome segregation protein
SMC1 homolog"
CDS 34..3735
/gene="SB1.8/DXS423E"
/note="mitosis-specific chromosome segregation protein
SMC1 homolog"
/codon_start=1
/protein_id="AAB34405.1"
/translation="MGFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDA
ISFVLGEKTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGGS
SEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISR
SGDVAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVR
AQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE
QQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMD
ELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE
LEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE
EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIK
RLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGE
PETFLPLDYLEVKPTDEKLRELKGAKLVIDVIRYEPPHIKKALQYACGNALVCDNVED
ARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLT
EELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESE
LANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVK
RQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEE
QRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTA
IETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSI
YAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEK
LESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKAL
SRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHS
YKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVY
PEQGDCVISKVLTFDLTKYPDANPNPNEQ"
BASE COUNT 1522 a 1134 c 1430 g 1087 t
ORIGIN
1 gcctgtccta ctgccgccgg cgccgcggcc gtcatggggt tcctgaaact gattgagatt
61 gagaacttta agtcgtacaa gggtcgacag attatcggac catttcagag gttcaccgcc
121 atcattggac ccaatggctc tggtaagtca aatctcatgg atgccatcag ctttgtgcta
181 ggtgaaaaaa ccagcaacct gcgggtaaag accctgcggg acctgatcca tggagctcct
241 gtgggcaagc cagctgccaa ccgggccttt gtcagcatgg tctactctga ggagggtgct
301 gaggaccgta cctttgcccg tgtcattgta ggaggttctt ctgagtacaa gatcaacaac
361 aaagtggtcc aactacatga gtacagtgag gaattagaga agttgggcat tctcatcaaa
421 gctcgtaact tcctcgtttt ccagggtgct gtggaatcta ttgccatgaa gaaccccaaa
481 gagaggacag ctctatttga agagattagt cgttctgggg acgtggcgca ggagtatgac
541 aagcgaaaga aggaaatggt gaaggctgaa gaggacacac agtttaatta ccatcgcaag
601 aaaaatattg cggctgaacg caaggaagca aagcaggaga aagaagaggc tgaccggtac
661 cagcgcctga aggatgaggt agtacgggct caggtacagc tgcagctctt taagctttac
721 cataatgaag tggaaattga gaagctcaac aaggaactgg cctcaaagaa caaggagatc
781 gagaaggaca agaagcgtat ggacaaggtg gaggatgaac tgaaggagaa gaagaaggag
841 ctgggcaaaa tgatgcggga gcagcagcag attgagaagg agatcaagga gaaggactca
901 gaattgaacc agaagcggcc tcagtacatc aaagccaagg agaacacctc ccacaaaatc
961 aagaagctgg aagcagccaa gaagtctctg cagaatgctc agaagcacta caagaagcgt
1021 aaaggtgaca tggatgagct ggagaaggag atgctgtcag tggagaaggc tcggcaggag
1081 tttgaagaac ggatggaaga agagagtcag agtcagggca gagatttgac gttggaggag
1141 aatcaggtga agaaatacca ccggttgaaa gaagaagcca gcaagagagc agctaccctg
1201 gcccaggagc tggagaaatt caatcgagac cagaaagctg accaggaccg tctggatctg
1261 gaagaacgga agaaagtaga gacagaggcc aagatcaagc aaaagctgcg ggaaattgaa
1321 gagaatcaga agcggattga gaaactggag gaatacatca ccactagcaa gcagtcccta
1381 gaagagcaga agaagctaga gggggagctg acagaggagg tggagatggc caagcggcgt
1441 attgatgaaa tcaataagga gctgaaccag gtgatggagc agctagggga tgcccgcatc
1501 gaccgccagg agagcagccg ccagcagcga aaggcagaga taatggaaag catcaagcgc
1561 ctttaccctg gctctgtgta cggccgcctc attgacctat gccagcccac acaaaagaag
1621 tatcagattg ctgtaaccaa ggttttgggc aagaacatgg atgccattat tgtggactcg
1681 gagaagacag gccgggactg tattcagtat atcaaggagc agcgtgggga gcctgagacc
1741 ttcttgcctc ttgactacct ggaggtgaag cctacagatg agaaactccg ggagctgaag
1801 ggggccaagc tagtgattga tgtgattcgc tatgagccac ctcatatcaa aaaggccctg
1861 cagtatgctt gtggcaatgc ccttgtctgt gacaacgtgg aagatgcccg ccgcattgcc
1921 tttggaggcc accagcgcca caagacagtg gcactggatg gaaccctatt ccagaagtca
1981 ggagtgatct ctggtggggc cagtgacctg aaggccaagg cacggcgctg ggatgagaaa
2041 gcagtagaca agttgaaaga gaagaaggag cgcttgacag aggagctgaa agagcagatg
2101 aaggcaaaac ggaaagaggc agagctgcgt caggtgcagt ctcaggccca tggactgcag
2161 atgcggctca agtactccca gagtgaccta gaacagacca agacacgaca tctagccctg
2221 aatctgcagg aaaaatccaa gctggagagt gagctagcca actttgggcc tcgcattaat
2281 gatatcaaga ggatcattca gagccgagag agggaaatga aagacttgaa ggagaagatg
2341 aaccaggtag aggatgaggt gtttgaagag ttttgtcggg agattggtgt gcgcaacatc
2401 cgggagtttg aggaagaaaa ggtgaaacgg cagaatgaaa tcgccaagaa gcgtttggag
2461 tttgagaatc agaagactcg cttgggcatt cagttggatt ttgaaaagaa ccaactgaag
2521 gaggaccaag ataaagtaca catgtgggag cagacagtga aaaaagatga aaatgagata
2581 gaaaagctca aaaaggagga acaaagacac atgaagatca tagatgagac catggctcag
2641 ctacaagacc tgaagaatca gcatctggcc aagaagtcgg aagtgaatga caagaatcat
2701 gagatggagg agattcgtaa gaaactcggg ggcgccaaca aggaaatgac ccatttacag
2761 aaggaggtga cagccattga gaccaagctt gaacagaagc gcagtgaccg tcacaacttg
2821 ctacaggcct gtaagatgca ggacattaag ttgccactgt caaaaggcac catggatgat
2881 attagtcagg aagagggtag ctcccagggg gaggactcag tgagtggttc acagagaatt
2941 tccagtatct atgcacgaga ggccctcatt gagattgact acggtgatct gtgtgaggat
3001 ctgaaggatg cccaggctga ggaagagatc aagcaagaga tgaacacact gcagcagaag
3061 ctgaatgagc agcagagtgt gcttcagcgt attgccgccc ccaacatgaa ggccatggaa
3121 aagctggaaa gtgtccgaga caagttccag gagacctcag atgagtttga agcagcccga
3181 aagcgagcaa agaaggccaa gcaggcattc gaacagatca agaaggagcg ctttgaccgc
3241 ttcaatgctt gttttgaatc tgtggctacc aacattgatg agatctataa ggccctgtcc
3301 cgcaatagca gtgcccaggc attcctgggc cctgagaacc ctgaagagcc ctacttggat
3361 ggcatcaact acaactgtgt ggctcctggg aaacgcttcc ggcctatgga caacttgtca
3421 ggcggggaga agacagtggc agctctggcc ctgctctttg ccatccacag ctacaagcca
3481 gcccccttct tcgtcctgga tgagattgat gctgccttgg ataacaccaa cattggcaag
3541 gtggcaaatt acatcaagga gcagtcgact tgcaacttcc aggccatcgt catctctctc
3601 aaggaggagt tctacaccaa ggccgagagc ctcattggag tctatcctga gcaaggggac
3661 tgtgtgatca gcaaagtcct gaccttcgac ctcaccaagt acccagatgc caaccccaac
3721 cccaatgagc agtagcagta tttttgccct cccgccctgt ctggatccct aagctgtccc
3781 tctcccaatc tctggatatt tgactcccaa ccttccccct acctcctggc cctttttggt
3841 gtagtcatgg gatttaggca ctgctaatca agcatgaaga ggaacagagg tgatgttagg
3901 tctggagcaa aaattcctga acgacaggga gtattctggc ctctgaaagg aggtgctgag
3961 ctgaacaggg ccatctgtnc atcacacaca cccnnttctc cctcatcacc cataatcgtg
4021 gnccccttgg ctcttgccca ctgtgtgtgt gggtatgtat gtgtgtatgt atgtatccgc
4081 atgtgtgcat gtgagtatgt ttgcaaaata ataaaggata ttggagacct gttttagaag
4141 gagcctaggc tgaatttgat tccaagagag cttaggatga cagcacccct gagctgggca
4201 aaggtactca ggacctcata ggagtcttag gcagttacct gaaactgcct tcattcactc
4261 atttgtgtat tcattcattt atgtattcat cagacacata ccgaacaccc tctatttgtc
4321 aggctctgtg cttggaatac agagttgaat cagacatgat ctctaccctc ctagtaagga
4381 gatacagtgg gttcatgaat gactatagtt agctgaatgt catatgtacn nttnnngaat
4441 ttgagaagtg gntgatcccc tctaggcttc ctggaggtca catttaagct agaccttgac
4501 aaattggtag gatttggtca ggcactagga gtggagcatg agctctgggg acagacagtt
4561 atgggttctg gtcccacttt ttatcactta ctagttgttt gaccttgggc aagtcatttg
4621 accttctgtg cctcagtttc ctcatctgta aaatggggct aacaatatta cctacctcat
4681 aggatttaat gatgtcaagc tcctcactgn agnccttatn ccnttcgtgn agcccactag
4741 gtgccgaccc ctcagaatat aatcctcatg cctgacccct gagagcttct gatcccagct
4801 attaggacag aagaagcctc caaatctgga aggtgctgaa tgccctgctg actgggaaag
4861 tttcagggca ctgatggggt ctacctggta agcggagggc ctgaggaaac ctgtagcttc
4921 aatcatgtct ggtaaccggg tgcctgagcc ccaatctggg ttgtgaggaa ataggggaga
4981 ggtatcctgg gccacatccc agcctaacac ctgtgaggtt cattttagga actaacctca
5041 ttagctataa ggatcatgca gaggcagcaa agccgggtgc gatgagctca gcctttactc
5101 attcacatac accatcacac tttaattcca atctgtatat tgctttttaa aagttaagtc
5161 cattctaatn ncccaaatat gcatgaattc
//