LOCUS S77770 3440 bp DNA linear HUM 10-AUG-1999
DEFINITION Homo sapiens voltage-gated chloride channel (CIC-2) gene, complete
cds.
ACCESSION S77770
VERSION S77770.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3440)
AUTHORS Cid,L.P., Montrose-Rafizadeh,C., Smith,D.I., Guggino,W.B. and
Cutting,G.R.
TITLE Cloning of a putative human voltage-gated chloride channel (CIC-2)
cDNA widely expressed in human tissues
JOURNAL Hum. Mol. Genet. 4 (3), 407-413 (1995)
PUBMED 7795595
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 166235] from the original journal article.
FEATURES Location/Qualifiers
source 1..3440
/organism="Homo sapiens"
/mol_type="unassigned DNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
gene <308..>3004
/gene="CIC-2"
mRNA <308..>3004
/gene="CIC-2"
/product="voltage-gated chloride channel"
CDS 308..3004
/gene="CIC-2"
/note="mismatch(412[A->V])"
/codon_start=1
/product="voltage-gated chloride channel"
/protein_id="AAB34722.2"
/translation="MAAAAAEEGMEPRALQHEQTLMYGRYTQDLGAFAKEEAARIRLG
GPEPWKGPPSSRAAPELLEYGRSRCARCRVCSVRCHKFLVSRVGEDWIFLVLLGLLMA
LVSWVMDYAIAACLQAQQWMSRGLNTSILLQYLAWVTYPVVLITFSAGFTQILAPQAV
GSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCALGSGMPLGKEGPFVHIASMCAAL
LSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYW
RGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFG
GALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLS
QKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKFWMSALAT
TIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAALA
GAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILL
GSIERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPSPEASVCFQVNTEDS
AFPAARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEK
LESCEKRKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLV
ERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLAS
FRDSATSSSDTETTEVHALWGPHSRHGLPREGSPSDSDDKCQ"
BASE COUNT 674 a 1056 c 1006 g 704 t
ORIGIN
1 ttcggccttc ccagcgcccc ttgcgcctct cgggaggccc cagcgcggac ccagcctggc
61 tgggccgtcc cctccggatg ggccggcggg cggagcagcg cagaggcacc gccctcggcc
121 cgcccgccgg ggaggggacg cgagcgggag gctcgccagc ggcgcccgcc gggggcccgc
181 cgcactctgc tctcggcctc ccgggctgcg gggacgggac ggctgccggc gcggactttg
241 cgggccggga gccgagtcca ggacagagcc ggaaccgccg agggaggcga gagggcagtg
301 cgcggagatg gcggccgcgg cggcggagga agggatggag ccacgggcgc tgcagcacga
361 gcagaccctg atgtatggcc ggtacactca ggaccttggg gcctttgcca aagaggaagc
421 tgctcggatt cgcctgggag ggcctgaacc ctggaaaggt cccccttcct ctcgggctgc
481 cccagagctc ttggaatatg gacggagccg ttgcgcccga tgccgcgtct gttctgtccg
541 ctgccacaag ttcctagtat ccagggttgg tgaagattgg atcttcctgg tcctgctggg
601 gcttctcatg gcattggtca gctgggtcat ggactatgcc attgctgcct gtctgcaagc
661 ccagcagtgg atgtcccggg gcttgaacac cagcatcttg ctccagtacc tggcctgggt
721 cacctaccct gttgtcctca tcactttctc agccggattc acacagatcc tggcccctca
781 ggctgtcggc tctggcatcc ctgagatgaa gaccatcttg cggggagtgg tgctgaaaga
841 atacctcaca ctcaagacct ttatagctaa ggtcattggg ctgacctgcg ccctaggcag
901 cgggatgccg cttggcaaag agggcccttt tgtgcatatc gcaagcatgt gtgctgccct
961 tctcagcaag ttcctctccc tctttggggg tatctatgag aatgaatccc ggaacacaga
1021 gatgctggct gccgcctgtg ccgtgggggt gggctgctgc ttcgcggcac ctattggagg
1081 cgtcctcttc agcatcgagg tcacctccac cttctttgca gtgcggaact actggcgggg
1141 cttcttcgct gccaccttca gtgccttcat cttccgggtc ttggcagtct ggaaccggga
1201 tgaagagact attacagccc tcttcaaaac ccgattccgg ctcgacttcc cctttgacct
1261 gcaggagctg ccagcctttg ctgtcattgg tattgctagt ggcttcggtg gagccctctt
1321 tgtctacctg aaccggaaga ttgtccaggt gatgcggaag cagaaaacca tcaatcgctt
1381 cctcatgagg aaacgcctgc tcttcccggc tctggtgacc ctgctcatct ccacgctgac
1441 cttcccccct ggctttggac agttcatggc tggacagctc tcacagaaag agacgctggt
1501 caccctgttt gacaatcgga cgtgggtccg ccagggcctg gtggaggagc tagaaccacc
1561 cagcacctca caggcctgga acccaccacg tgccaacgtc ttcctcaccc tggtcatctt
1621 cattctcatg aagttctgga tgtctgcact ggccaccacc atcccagttc cctgtggggc
1681 cttcatgcct gtctttgtca ttggagcagc atttgggcgt ctggtgggtg aaagcatggc
1741 tgcctggttc ccagatggaa ttcatacgga cagcagcacc taccggattg tgcctggggg
1801 ctacgctgtg gtcggggcag ctgcgctggc aggagcggtg acacacacag tgtccacggc
1861 tgtgatcgtg ttcgagctca caggccagat tgcccacatc ctgcctgtca tgatcgccgt
1921 catcctggcc aacgctgtcg cccagagtct gcagccctcc ctctatgaca gcatcatccg
1981 aatcaagaaa ctgccctacc tgcctgagct cggctggggc cgccaccagc agtaccgggt
2041 gcgtgtggag gacatcatgg tgcgggatgt tccccatgtg gccctcagct gcaccttccg
2101 ggacctgcgt ttggcactgc acaggaccaa gggccgaatg ctggccctag tggagtcccc
2161 tgagtccatg attctgctgg gctccatcga gcgttcacag gtggtggcat tgttgggggc
2221 ccagctgagc ccagcccgcc ggcggcagca catgcaggag cgcagagcca cccagacctc
2281 tccactatct gatcaggagg gtccccctag ccctgaggct tctgtctgct tccaggtgaa
2341 cacagaagac tcagccttcc cagcagcccg gggggagacc cacaagcccc taaagcctgc
2401 actcaagagg gggcccagtg tcaccaggaa cctcggagag agtcccacag ggagcgcaga
2461 gtcggcaggc atcgccctcc ggagcctctt ctgtggcagt ccaccccctg aggctgcttc
2521 ggagaagttg gaatcctgtg agaagcgcaa gctgaagcgt gtccgaatct ccctggcaag
2581 tgacgcggac ctggaaggcg agatgagccc tgaagagatt ctggagtggg aggagcagca
2641 actagatgaa cctgtcaact tcagtgactg caaaattgat cctgctccct tccagctggt
2701 ggagcggacc tctttgcaca agactcacac tatcttctca ctgctgggag tggaccatgc
2761 ttatgtcacc agtattggca gactcattgg aatcgttact ctaaaggagc tccggaaggc
2821 catcgagggc tctgtcacag cacagggtgt gaaagtccgg ccgcccctcg ccagcttccg
2881 agacagtgcc accagcagca gtgacacgga gaccactgag gtgcatgcac tctgggggcc
2941 ccactcccgt catggcctcc cccgggaggg cagcccttcc gacagcgacg acaaatgcca
3001 atgagcccct cgtgggtggc ctaggatggt gctagccatg cccgtcagcc cagaatgtgc
3061 atctttcatt ccttctgcct tcggaaggca ggaggcagct acagctggag gctgcacccc
3121 agccccctcc agacctgggg tgccagcttc tcccagttca tcctacctgg aatctgaccc
3181 actacccacc tgcaacaagt cttccagagg caggaagata ggccctgccc tggcaggatg
3241 ggttggggtc acttgacccc tgctccccct ttgaggggga aggggtggaa ctaagatggg
3301 tttataactg gaacctccaa tgaccagact gtatatagag atttacaaag atttttatat
3361 taatttaata aaacaaattc ttaaatagaa caaaataaac acctaatgag ccactttata
3421 tataaaaaaa aaaaaaaaaa
//