LOCUS S75213 2319 bp mRNA linear HUM 26-JUL-2016
DEFINITION type-IVA cyclic AMP specific phosphodiesterase HPDE4A [human,
T-cells, mRNA Partial, 2319 nt].
ACCESSION S75213
VERSION S75213.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2319)
AUTHORS Sullivan,M., Egerton,M., Shakur,Y., Marquardsen,A. and Houslay,M.D.
TITLE Molecular cloning and expression, in both COS-1 cells and S.
cerevisiae, of a human cytosolic type-IVA, cyclic AMP specific
phosphodiesterase (hPDE-IVA-h6.1)
JOURNAL Cell. Signal. 6 (7), 793-812 (1994)
PUBMED 7888306
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 160242] from the original journal article.
FEATURES Location/Qualifiers
source 1..2319
/db_xref="H-InvDB:HIT000216592"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2319
/gene="type-IVA cyclic AMP specific phosphodiesterase
HPDE4A"
CDS 1..2005
/gene="type-IVA cyclic AMP specific phosphodiesterase
HPDE4A"
/codon_start=2
/protein_id="AAB33798.1"
/translation="ATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFK
RMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQP
PPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI
FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLH
AADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALM
YNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLL
ADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMA
EFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEIL
DTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIP
CTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQS
TGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTA
AEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT"
BASE COUNT 551 a 693 c 629 g 446 t
ORIGIN
1 ggccacgctg tcagaagaaa cgtgtcagca gttggcccgg gagactctgg aggagctgga
61 ctggtgtctg gagcagctgg agaccatgca gacctatcgc tctgtcagcg agatggcctc
121 gcacaagttc aaaaggatgt tgaaccgtga gctcacacac ctgtcagaaa tgagcaggtc
181 cggaaaccag gtctcagagt acatttccac aacattcctg gacaaacaga atgaagtgga
241 gatcccatca cccacgatga aggaacgaga aaaacagcaa gcgccgcgac caagaccctc
301 ccagccgccc ccgccccctg taccacactt acagcccatg tcccaaatca cagggttgaa
361 aaagttgatg catagtaaca gcctgaacaa ctctaacatt ccccgatttg gggtgaagac
421 cgatcaagaa gagctcctgg cccaagaact ggagaacctg aacaagtggg gcctgaacat
481 cttttgcgtg tcggattacg ctggaggccg ctcactcacc tgcatcatgt acatgatatt
541 ccaggagcgg gacctgctga agaaattccg catccctgtg gacacgatgg tgacatacat
601 gctgacgctg gaggatcact accacgctga cgtggcctac cataacagcc tgcacgcagc
661 tgacgtgctg cagtccaccc acgtactgct ggccacgcct gcactagatg cagtgttcac
721 ggacctggag attctcgctg ccctcttcgc ggctgccatc cacgatgtgg atcaccctgg
781 ggtctccaac cagttcctca tcaacaccaa ttcggagctg gcgctcatgt acaacgatga
841 gtcggtgctc gagaatcacc acctggccgt gggcttcaag ctgctgcagg aggacaactg
901 cgacatcttc cagaacctca gcaagcgcca gcggcagagc ctacgcaaga tggtcatcga
961 catggtgctg gccacggaca tgtccaagca catgaccctc ctggctgacc tgaagaccat
1021 ggtggagacc aagaaagtga ccagctcagg ggtcctcctg ctagataact actccgaccg
1081 catccaggtc ctccggaaca tggtgcactg tgccgacctc agcaacccca ccaagccgct
1141 ggagctgtac cgccagtgga cagaccgcat catggccgag ttcttccagc agggtgaccg
1201 agagcgcgag cgtggcatgg aaatcagccc catgtgtgac aagcacactg cctccgtgga
1261 gaagtctcag gtgggtttta ttgactacat tgtgcaccca ttgtgggaga cctgggcgga
1321 ccttgtccac ccagatgccc aggagatctt ggacactttg gaggacaacc gggactggta
1381 ctacagcgcc atccggcaga gcccatctcc gccacccgag gaggagtcaa gggggccagg
1441 ccacccaccc ctgcctgaca agttccagtt tgagctgacg ctggaggagg aagaggagga
1501 agaaatatca atggcccaga taccgtgcac agcccaagag gcattgactg cgcagggatt
1561 gtcaggagtc gaggaagctc tggatgcaac catagcctgg gaggcatccc cggcccagga
1621 gtcgttggaa gttatggcac aggaagcatc cctggaggcc gagctggagg cagtgtattt
1681 gacacagcag gcacagtcca caggcagtgc acctgtggct ccggatgagt tctcgtcccg
1741 ggaggaattc gtggttgctg taagccacag cagcccctct gccctggctc ttcaaagccc
1801 ccttctccct gcttggagga ccctgtctgt ttcagagcat gccccgggcc tcccgggcct
1861 cccctccacg gcggccgagg tggaggccca acgagagcac caggctgcca agagggcttg
1921 cagtgcctgc gcagggacat ttggggagga cacatccgca ctcccagctc ctggtggcgg
1981 ggggtcaggt ggagacccta cctgatcccc agacctctgt ccctgttccc ctccactcct
2041 cccctcactc ccctgctccc ccgaccacct cctcctctgc ctcaaagact cttgtcctct
2101 tgtccctcct gagaaaaaag aaaacgaaaa gtggggtttt tttctgtttt ctttttttcc
2161 cctttccccc tgcccccacc cacggggcct ttttttggag gtgggggctg gggaatgagg
2221 ggctgaggtc ccggaaggga ttttattttt ttgaatttta attgtaacat ttttagaaaa
2281 agaacaaaaa aagaaaaaaa aaagaaagaa acacagcaa
//