LOCUS S75037 2994 bp mRNA linear HUM 26-JUL-2016
DEFINITION pancreatic peptidylglycine alpha-amidating
monooxygenase=membrane-bound isoform {alternatively spliced, clone
PAM-3, transmembrane domain (Ba region)} [human, islet cell tumor
cell line QGP-1, mRNA Partial, 2994 nt].
ACCESSION S75037
VERSION S75037.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2994)
AUTHORS Tateishi,K., Arakawa,F., Misumi,Y., Treston,A.M., Vos,M. and
Matsuoka,Y.
TITLE Isolation and functional expression of human pancreatic
peptidylglycine alpha-amidating monooxygenase
JOURNAL Biochem. Biophys. Res. Commun. 205 (1), 282-290 (1994)
PUBMED 7999037
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 159679] from the original journal article.
Erratum:[Biochem Biophys Res Commun 1995 Jan 17;206(2):805]
FEATURES Location/Qualifiers
source 1..2994
/db_xref="H-InvDB:HIT000216574"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2994
/gene="pancreatic peptidylglycine alpha-amidating
monooxygenase, PAM"
CDS join(81..2762,2764..2994)
/gene="pancreatic peptidylglycine alpha-amidating
monooxygenase, PAM"
/note="membrane-bound isoform; PAM"
/codon_start=1
/product="pancreatic peptidylglycine alpha-amidating
monooxygenase"
/protein_id="AAB32775.1"
/translation="MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSNECLG
TTRPVVPIDSSDFALDIRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVH
HMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSK
YFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNS
DISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPV
DVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVA
PDMFRTIPPEANIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYS
LLSKLLGEREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHERGN
AILVRDRIHKFHRLVSTLRPPESRVFSLQQPPPGEGTWEPEHTGDFHMEEALDWPGVY
LLPGQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNN
AAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPG
SDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQ
FTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPGL
LFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFDMPHDIVASEDGTVYIGDA
HTNTVWKFTLTEKLEHRSVKKAGIEVQEIKEAVVETKMENKPTSSELQKMQEKQKLIK
EPGSGVPVVLITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEHKLETSSGRVLGRFRGK
GSGGLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEEYSAPLPALAPSSS"
BASE COUNT 847 a 644 c 733 g 770 t
ORIGIN
1 ggcgccgctg cccaaccgcc agccccagcc ccgcgctgcg ctgcccggtc ctctcccggc
61 ggggtcgtat cggcgtggac atggctggcc gcgtccctag cctgctagtt ctccttgttt
121 ttccaagcag ctgtttggct ttccgaagcc cactttctgt ctttaagagg tttaaagaaa
181 ctaccagacc attttccaat gaatgtcttg gtaccaccag acccgtagtt cctattgatt
241 catcagattt tgcattggat attcgcatgc ctggggttac acctaaacag tccgatacat
301 acttctgcat gtctatgcga ataccagtgg atgaggaagc cttcgtgatt gacttcaagc
361 ctcgagccag catggatact gtccatcaca tgttactttt tggatgcaat atgccttcat
421 ccactggaag ttactggttt tgtgatgaag gaacctgtac agataaagcc aatattctgt
481 atgcctgggc gagaaatgct ccccctaccc ggctccccaa aggtgttgga ttcagagttg
541 gaggagagac tggaagtaaa tactttgtac tacaggtaca ctatggggat attagtgctt
601 ttagagataa taacaaggac tgttctggtg tgtccttaca cctcacacgt ctgccacagc
661 ctttaattgc tggcatgtac cttatgatgt ctgttgacac tgttatccca gcaggagaaa
721 aagtggtgaa ttctgacatt tcatgccatt ataaaaatta tccaatgcat gtctttgcct
781 atagagttca cactcaccat ttaggtaagg tagtaagtgg atacagagta agaaatggac
841 agtggacact gattggacgg cagagccctc agctgccaca ggctttctac cctgtggggc
901 atccagttga tgtaagtttt ggtgacctac tggctgcaag atgtgtattc actggtgaag
961 gaaggacaga agccacacac attggtggca cgtctagtga tgaaatgtgc aacttataca
1021 ttatgtatta catggaagcc aagcatgcag tttctttcat gacctgtacc cagaatgtag
1081 ctccagatat gttcagaacc ataccaccag aggccaacat tccaattccc gtgaagtctg
1141 atatggttat gatgcatgaa catcataaag aaacagaata taaagataag attcctttac
1201 tacagcagcc aaaacgagaa gaagaagaag tgttagacca gggtgatttc tattcactac
1261 tttccaagct gctaggagaa agggaagatg ttgttcatgt gcacaaatat aatcctacag
1321 aaaaggcaga atcagagtca gacctggtag ctgagattgc aaatgtagtc caaaaaaagg
1381 atcttggtcg atctgatgcc agagagggtg cagaacatga gaggggtaat gctattcttg
1441 tcagagacag aattcacaaa ttccacagac tagtatctac cttgaggcca ccagagagca
1501 gagttttctc attacagcag cccccacctg gtgaaggcac ctgggaacca gaacacacag
1561 gagatttcca catggaagag gcactggatt ggcctggagt atacttgtta ccaggccagg
1621 tttctggggt ggctctagac cctaagaata acctggtgat tttccacaga ggtgaccatg
1681 tctgggatgg aaactcgttt gacagcaagt ttgtttacca gcaaatagga ctcggaccaa
1741 ttgaagaaga cactattctt gtcatagatc caaataatgc tgcagtactc cagtccagtg
1801 gaaaaaatct gttttacttg ccacatggct tgagtataga taaagatggg aattattggg
1861 tcacagacgt ggctctccat caggtgttca aactggatcc aaacaataaa gaaggccctg
1921 tattaatcct gggaaggagc atgcaaccag gcagtgacca gaatcacttc tgtcaaccca
1981 ctgatgtggc tgtggatcca ggcactggag ccatttatgt atcagatggt tactgcaaca
2041 gcaggattgt gcagttttca ccaagtggaa agttcatcac acagtgggga gaagagtctt
2101 cagggagcag tcctctgcca ggccagttca ctgttcctca cagcttggct cttgtgcctc
2161 ttttgggcca attatgtgtg gcagaccggg aaaatggtcg gatccagtgt tttaaaactg
2221 acaccaaaga atttgtgaga gagattaagc attcatcatt tggaagaaat gtatttgcaa
2281 tttcatatat accaggcttg ctctttgcag tgaatgggaa gcctcatttt ggggaccaag
2341 aacctgtaca aggatttgtg atgaactttt ccaatgggga aattatagac atcttcaagc
2401 cagtgcgcaa gcactttgat atgcctcatg atattgttgc atctgaagat gggactgtgt
2461 acattggaga tgctcatacc aacaccgtgt ggaagttcac cttgactgag aaattggaac
2521 atcgatcagt taaaaaggct ggcattgagg tccaggaaat caaagaggca gttgttgaaa
2581 ccaaaatgga gaacaaaccc acctcctcag aattgcagaa gatgcaagag aaacagaagc
2641 tgatcaaaga gccaggctcg ggagtgcctg ttgttctcat tacaaccctt ctggttattc
2701 cggtggttgt cctgctggcc attgccatat ttattcggtg gaaaaaatca agggcctttg
2761 gaggattctg aacacaaact cgagacgagt tcaggaagag tactgggaag atttagagga
2821 aagggaagtg gaggcttaaa ccttggtaat ttctttgcaa gccgtaaggg ctacagtcga
2881 aaagggtttg accggcttag cactgagggc agtgaccaag agaaagagga tgatggaagt
2941 gaatcagaag aggagtattc agcacctctg cctgcgctcg caccttcctc ctcc
//