LOCUS S74774 1605 bp mRNA linear HUM 17-JUL-2000
DEFINITION p59fyn(T)=OKT3-induced calcium influx regulator [human, Jurkat J6 T
cell line, mRNA Partial, 1605 nt].
ACCESSION S74774
VERSION S74774.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1605)
AUTHORS Rigley,K., Slocombe,P., Proudfoot,K., Wahid,S., Mandair,K. and
Bebbington,C.
TITLE Human p59fyn(T) regulates OKT3-induced calcium influx by a
mechanism distinct from PIP2 hydrolysis in Jurkat T cells
JOURNAL J. Immunol. 154 (3), 1136-1145 (1995)
PUBMED 7822789
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 159094] from the original journal article.
This sequence comes from Fig. 1.
FEATURES Location/Qualifiers
source 1..1605
/db_xref="H-InvDB:HIT000216561"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat J6"
/cell_type="T-cell"
CDS 1..1605
/note="OKT3-induced calcium influx regulator; conceptual
translation differs from that in published reference"
/codon_start=1
/product="tyrosine kinase p59fyn(T)"
/protein_id="AAB33113.2"
/translation="MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGV
TSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLS
FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAE
RQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR
AQFETLQQLVQHYSEKADGLCFNLTVIASSCTPQTSGLAKDAWEVARRSLCLEKKLGQ
GCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP
IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSAN
ILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPERALYGRFTIKSDVWSFG
ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP
TFEYLQSFLEDYFTATEPQYQPGENL"
BASE COUNT 459 a 375 c 417 g 354 t
ORIGIN
1 atgggctgtg tgcaatgtaa ggataaagaa gcaacaaaac tgacggagga gagggacggc
61 agcctgaacc agagctctgg gtaccgctat ggcacagacc ccacccctca gcactacccc
121 agcttcggtg tgacctccat ccccaactac aacaacttcc acgcagccgg gggccaagga
181 ctcaccgtct ttggaggtgt gaactcttcg tctcatacgg ggaccttgcg tacgagagga
241 ggaacaggag tgacactctt tgtggccctt tatgactatg aagcacggac agaagatgac
301 ctgagttttc acaaaggaga aaaatttcaa atattgaaca gctcggaagg agattggtgg
361 gaagcccgct ccttgacaac tggagagaca ggttacattc ccagcaatta tgtggctcca
421 gttgactcta tccaggcaga agagtggtac tttggaaaac ttggccgaaa agatgctgag
481 cgacagctat tgtcctttgg aaacccaaga ggtacctttc ttatccgcga gagtgaaacc
541 accaaaggtg cctattcact ttctatccgt gattgggatg atatgaaagg agaccatgtc
601 aaacattata aaattcgcaa acttgacaat ggtggatact acattaccac ccgggcccag
661 tttgaaacac ttcagcagct tgtacaacat tactcagaga aagctgacgg tttgtgtttt
721 aacttaactg tgattgcatc gagttgtacc ccacaaactt ctggattggc taaagatgct
781 tgggaagttg cacgtcgttc gttgtgtctg gagaagaagc tgggtcaggg gtgtttcgct
841 gaagtgtggc ttggtacctg gaatggaaac acaaaagtag ccataaagac tcttaaacca
901 ggcacaatgt cccccgaatc attccttgag gaagcgcaga tcatgaagaa gctgaagcac
961 gacaagctgg tccagctcta tgcagtggtg tctgaggagc ccatctacat cgtcaccgag
1021 tatatgaaca aaggaagttt actggatttc ttaaaagatg gagaaggaag agctctgaaa
1081 ttaccaaatc ttgtggacat ggcagcacag gtggctgcag gaatggctta catcgagcgc
1141 atgaattata tccatagaga tctgcgatca gcaaacattc tagtggggaa tggactcata
1201 tgcaagattg ctgacttcgg attggcccga ttgatagaag acaatgagta cacagcaaga
1261 caaggtgcaa agttccccat caagtggacg gcccccgagc gagccctgta cgggaggttc
1321 acaatcaagt ctgacgtgtg gtcttttgga atcttactca cagagctggt caccaaagga
1381 agagtgccat acccaggcat gaacaaccgg gaggtgctgg agcaggtgga gcgaggctac
1441 aggatgccct gcccgcagga ctgccccatc tctctgcatg agctcatgat ccactgctgg
1501 aaaaaggacc ctgaagaacg ccccactttt gagtacttgc agagcttcct ggaagactac
1561 tttaccgcga cagagcccca gtaccaacct ggtgaaaacc tgtaa
//