LOCUS S62907 2189 bp mRNA linear HUM 25-AUG-1993
DEFINITION gamma-aminobutyric acidA receptor alpha 2 subunit [human, fetal
brain, mRNA, 2189 nt].
ACCESSION S62907
VERSION S62907.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2189)
AUTHORS Hadingham,K.L., Wingrove,P., Le Bourdelles,B., Palmer,K.J.,
Ragan,C.I. and Whiting,P.J.
TITLE Cloning of cDNA sequences encoding human alpha 2 and alpha 3
gamma-aminobutyric acidA receptor subunits and characterization of
the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-,
alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA
receptors
JOURNAL Mol. Pharmacol. 43 (6), 970-975 (1993)
PUBMED 8391122
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 134256] from the original journal article.
FEATURES Location/Qualifiers
source 1..2189
/db_xref="H-InvDB:HIT000216015"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2189
/gene="gamma-aminobutyric acidA receptor alpha 2 subunit,
GABAA receptor alpha 2"
CDS 214..1569
/gene="gamma-aminobutyric acidA receptor alpha 2 subunit,
GABAA receptor alpha 2"
/note="GABAA receptor alpha 2"
/codon_start=1
/product="gamma-aminobutyric acidA receptor alpha 2
subunit"
/protein_id="AAB27278.1"
/translation="MKTKLNIYNIEFLLFVFLVWDPARLVLANIQEDEAKNNITIFTR
ILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL
KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRL
TVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQY
DLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNR
ESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV
NYFTKRGWTWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSAT
TPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVLGVS
P"
BASE COUNT 640 a 465 c 419 g 665 t
ORIGIN
1 cctagcgctc ctctccggct tccaccagcc catcgctcca cgctctcttg gctgctgcag
61 tctcggtctc tctctctctc tctctctctc tctctctctc tctctctctc tctctctctc
121 tctctctctc tctctcccaa gtttcctatc tcgtcaagat cagggcaaaa gaagaaaaca
181 ccgaattctg cttgccgttt cagagcggcg gtgatgaaga caaaattgaa catctacaac
241 atcgagttcc tgctttttgt tttcttggtg tgggaccctg ccaggttggt gctggctaac
301 atccaagaag atgaggctaa aaataacatt accatcttta cgagaattct tgacagactt
361 ctggatggtt acgataatcg gcttagacca ggactgggag acagtattac tgaagtcttc
421 actaacatct acgtgaccag ttttggccct gtctcagata cagatatgga atatacaatt
481 gatgttttct ttcgacaaaa atggaaagat gaacgtttaa aatttaaagg tcctatgaat
541 atccttcgac taaacaattt aatggctagc aaaatctgga ctccagatac cttttttcac
601 aatgggaaga aatcagtagc tcataatatg acaatgccaa ataagttgct tcgaattcag
661 gatgatggga ctctgctgta taccatgagg cttacagttc aagctgaatg cccaatgcac
721 ttggaggatt tcccaatgga tgctcattca tgtcctctga aatttggcag ctatgcatat
781 acaacttcag aggtcactta tatttggact tacaatgcat ctgattcagt acaggttgct
841 cctgatggct ctaggttaaa tcaatatgac ctgctgggcc aatcaatcgg aaaggagaca
901 attaaatcca gtacaggtga atatactgta atgacagctc atttccacct gaaaagaaaa
961 attgggtatt ttgtgattca aacctatctg ccttgcatca tgactgtcat tctctcccaa
1021 gtttcattct ggcttaacag agaatctgtg cctgcaagaa ctgtgtttgg agtaacaact
1081 gtcctaacaa tgacaactct aagcatcagt gctcggaatt ctctccccaa agtggcttat
1141 gcaactgcca tggactggtt tattgctgtt tgttatgcat ttgtgttctc tgccctaatt
1201 gaatttgcaa ctgttaatta cttcaccaaa agaggatgga cttgggatgg gaagagtgta
1261 gtaaatgaca agaaaaaaga aaaggcttcc gttatgatac agaacaacgc ttatgcagtg
1321 gctgttgcca attatgcccc gaatctttca aaagatccag ttctctccac catctccaag
1381 agtgcaacca cgccagaacc caacaagaag ccagaaaaca agccagctga agcaaagaaa
1441 actttcaaca gtgttagcaa aattgacaga atgtccagaa tagtttttcc agttttgttt
1501 ggtaccttta atttagttta ctgggctaca tatttaaaca gagaacctgt attaggggtc
1561 agtccttgaa ttgagaccca tgttatcttt gggatgtata gcaacattaa atttggtttg
1621 ttttgctatg tacagtctga ctaataactg ctaatttgtg atccaacatg tacagtatgt
1681 atatagtgac atagcttacc agtagacctt taatggagac atgcatttgc taactcatgg
1741 aactgcagac agaaagcact ccatgcgaaa acagccattg ccttttttaa agatttaccc
1801 taggacctga tttaaagtga atttcaagtg acctgattaa tttcctattc ttccaaatga
1861 gatgaaaatg gggatcctgt acaacccttt gtggaccctt ttggtttagc tcttaagtag
1921 gggtattttc tactgttgct taattatgat ggaagataac attgtcattc ctagatgaat
1981 cctttgaagt aacaaacatt gtatctgaca tcagctctgt tcatgagtgc tcagagtccc
2041 tgctaatgta attggaagct tggtacacat aagaaaaact agagatttga aatctagcta
2101 tgaattactc tatatagtat ctatagccat gtacatatta cagcatgaca agctcgaaat
2161 aattatgagt cagcccgaaa gatgttaat
//