LOCUS S62035 2861 bp mRNA linear HUM 25-AUG-1993
DEFINITION Ras-specific guanine nucleotide-releasing factor=CDC25 homolog
[human, brain stem, mRNA, 2861 nt].
ACCESSION S62035
VERSION S62035.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2861)
AUTHORS Schweighoffer,F., Faure,M., Fath,I., Chevallier-Multon,M.C.,
Apiou,F., Dutrillaux,B., Sturani,E., Jacquet,M. and Tocque,B.
TITLE Identification of a human guanine nucleotide-releasing factor
(H-GRF55) specific for Ras proteins
JOURNAL Oncogene 8 (6), 1477-1485 (1993)
PUBMED 7684828
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 133284] from the original journal article.
FEATURES Location/Qualifiers
source 1..2861
/db_xref="H-InvDB:HIT000215980"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2861
/gene="Ras-specific guanine nucleotide-releasing factor,
H-GRF55"
CDS 1183..2652
/gene="Ras-specific guanine nucleotide-releasing factor,
H-GRF55"
/note="CDC25 homolog; H-GRF55"
/codon_start=1
/product="Ras-specific guanine nucleotide-releasing
factor"
/protein_id="AAB26881.1"
/translation="MYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSA
LSKQSSEVSMREESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVV
MTSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEF
VIRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAAN
IIRTLTQEDPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYE
EFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVAD
ICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLR
EALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQT
AYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT"
BASE COUNT 740 a 848 c 661 g 612 t
ORIGIN
1 attcggggtc ctttttggcc tacttggggt gagtcaacat aaggagtgca ggccacctta
61 gcctttgctt ctcaaaagtc atgggtcaat gaagtccttg gccaaggctg tccagcagta
121 ggccaagttc agggattggc tcaggcccct aatggacttc actgcatcca ggaatggtag
181 gtgattatct tttccgagag gccacctacc cagatcccag ttgtggacag cccatcccag
241 ccctcagagg ctcagaggct ctctgagtgc cctgccccaa aacaccctag gcaagacatt
301 atgccagagc ctcagctcta gggctgcctg gagcagagct cctgaatcac actggctccc
361 cagggctccc caggaacctc accattcctc ccccaatcca cacctctgct gccagagcaa
421 cgcaacgacc cagaatacac ccgttccctc ttctgttccc tcctcctgcc cccacctcag
481 gcctcactgg ggcagggtac atcttgcctc tctgccctga acttctgaaa cctcaatgat
541 cagattccca gggctctgag aaaacagaaa caaacatccc atccaggatg gatttacccc
601 ctaaaagtca ctgagatcat tcccaggggc ccagcagaca gtgtccttcc tttcccagca
661 gcagtgccct gcagaacaaa gaggctggtt cagagccagc tctcagccct atggccttgg
721 ctgagtccct taacctttct gagactcagt ttcctacctg tgacattcct gcagttatcc
781 tgtaggaata agagtgccta cgtcctgggg caacagtgag ggttaaaaga tcaatcctat
841 cctgtgtgca acgtggagca gacagcctcg atgagacaag ctatggtttg caatgttctg
901 gatgtataac ctgtttccag cctggcctga ggtggaaccc tgtcatgagg atggtcgctg
961 gagctcctgt ttgccagtgg ccagaacaat aagctcctgt acggtgaacc ccccaagtcc
1021 ccgcgcgcca cccgcaagtt ctcctcgccg ccacctctgt ccatcaccaa gacatcgtca
1081 ccgagccgcc ggcggaagct ctccctgaac atccccatca tcactggcgg caaggccctg
1141 gacctggccg ccctcagctg caactccaat ggctacacca gcatgtactc ggccatgtca
1201 cccttcagca aggccacgct ggacaccagc aagctctatg tgtccagcag cttcaccaac
1261 aagattccag atgagggcga tacgacccct gagaagcccg aagacccttc agcgctcagc
1321 aagcagagct cagaagtctc catgagagag gagtcagata ttgatcaaaa ccagagtgat
1381 gatggtgata ctgaaacatc accaactaaa tctccaacaa cacccaaatc agtcaaaaac
1441 aaaaattctt cagagttccc actcttttcc tataacaatg gagtcgtcat gacctcctgt
1501 cgtgaactgg acaataaccg cagtgccttg tcggccgcct ctgcctttgc catagcaacc
1561 gccggggcca acgagggcac cccaaacaag gagaagtacc ggaggatgtc cttagccagt
1621 gcagggtttc ccccagacca gaggaatgga gacaaggagt ttgtgatccg cagagcagcc
1681 accaatcgtg tcttgaacgt gctccgccac tgggtgtcca agcactctca ggactttgag
1741 accaacgatg agctcaaatg caaggtgatc ggcttcctgg aagaagtcat gcacgacccg
1801 gagctcctga cccaggagcg gaaggctgca gccaacatca tcaggactct gacccaggag
1861 gacccaggtg acaaccagat cacgctggag gagatcacgc agatggctga aggcgtgaag
1921 gctgagccct ttgaaaacca ctcagccctg gagatcgcgg agcagctgac cctgctagat
1981 cacctcgtct tcaagaagat tccttatgag gagttcttcg gacaaggatg gatgaaactg
2041 gaaaagaatg aaaggacccc ttatatcatg aaaaccacta agcacttcaa tgacatcagt
2101 aacttgattg cttcagaaat catccgcaat gaggacatca acgccagggt gagcgccatc
2161 gagaagtggg tggccgtagc tgacatatgc cgctgcctcc acaactacaa tgccgtactg
2221 gagatcacct cgtccatgaa ccgcagtgca atcttccggc tcaaaaagac gtggctcaaa
2281 gtctctaagc agactaaagc tttgattgat aagctccaaa agcttgtgtc atctgagggc
2341 agatttaaga atctcagaga agctttgaaa aattgtgacc caccctgtgt cccttacctg
2401 gggatgtacc tcaccgacct ggccttcatc gaggagggga cgcccaatta cacggaagac
2461 ggcctggtca acttctccaa gatgaggatg atatcccata ttatccgaga gattcgccag
2521 tttcaacaaa ctgcctacaa aatagagcac caagcaaagg taacgcaata tttactggac
2581 caatcttttg taatggatga agaaagcctc tacgagtctt ctctccgaat agaaccaaaa
2641 ctccccacct gaagctgtgc ccagcccaga cccagctgct cccggggaca tgtgctagat
2701 gatactgtac atattcgttt ggtttcactg gattttcttc ttcagtatgt gcttctccaa
2761 gaatacaaat cgtccttgtt cttagattcc tgtagaaccg gaatatgaat ttctgcaccg
2821 tttcagactt cgcccaccca tccctcccct cgcccgaatt c
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