LOCUS S57498 4105 bp mRNA linear HUM 29-JAN-2002
DEFINITION endothelin ET-A receptor [human, mRNA, 4105 nt].
ACCESSION S57498
VERSION S57498.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4105)
AUTHORS Arai,H., Nakao,K., Hosoda,K., Ogawa,Y., Nakagawa,O., Komatsu,Y. and
Imura,H.
TITLE Molecular cloning of human endothelin receptors and their
expression in vascular endothelial cells and smooth muscle cells
JOURNAL Jpn. Circ. J. 56 (Suppl 5), 1303-1307 (1992)
PUBMED 1291713
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 128422] from the original journal article.
This sequence comes from Fig. 5.
FEATURES Location/Qualifiers
source 1..4105
/db_xref="H-InvDB:HIT000215852"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 485..1768
/note="conceptual translation presented here differs from
translation in publication; ET-AR"
/codon_start=1
/product="endothelin ET-A receptor"
/protein_id="AAB25530.2"
/translation="METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTE
LSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLL
RIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKL
FPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
PEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
LMTCEMLNRXNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYN
EMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSK
SLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN"
BASE COUNT 1138 a 859 c 843 g 1263 t
ORIGIN
1 gaattcgcgg ccgcctcttg cggtcccaga gtggagtgga aggtctggag ctttgggagg
61 agacggggag gacagactgg aggcgtgttc ctccggagtt ttctttttcg tgcgagccct
121 cgcgcgcgcg tacagtcatc ccgctggtct gacgattgtg gagaggcggt ggagaggctt
181 catccatccc acccggtcgt cgccggggat tggggtccca gcgacacctc cccgggagaa
241 gcagtgccca ggaagttttc tgaagccggg gaagctgtgc agccgaagcc gccgccgcgc
301 cggagcccgg gacaccggcc accctccgcg ccacccaccc tcgctttctc cggcttcctc
361 tggcccaggc gccgcgcgga cccggcagct gtctgcgcac gccgagctcc acggtgaaaa
421 aaaaagtgaa ggtgtaaaag cagcacaagt gcaataagag atatttcctc aaatttgcct
481 caagatggaa accctttgcc tcagggcatc cttttggctg gcactggttg gatgtgtaat
541 cagtgataat cctgagagat acagcacaaa tctaagcaat catgtggatg atttcaccac
601 ttttcgtggc acagagctca gcttcctggt taccactcat caacccacta atttggtcct
661 acccagcaat ggctcaatgc acaactattg cccacagcag actaaaatta cttcagcttt
721 caaatacatt aacactgtga tatcttgtac tattttcatc gtgggaatgg tggggaatgc
781 aactctgctc aggatcattt accagaacaa atgtatgagg aatggcccca acgcgctgat
841 agccagtctt gcccttggag accttatcta tgtggtcatt gatctcccta tcaatgtatt
901 taagctgctg gctgggcgct ggccttttga tcacaatgac tttggcgtat ttctttgcaa
961 gctgttcccc tttttgcaga agtcctcggt ggggatcacc gtcctcaacc tctgcgctct
1021 tagtgttgac aggtacagag cagttgcctc ctggagtcgt gttcagggaa ttgggattcc
1081 tttggtaact gccattgaaa ttgtctccat ctggatcctg tcctttatcc tggccattcc
1141 tgaagcgatt ggcttcgtca tggtaccctt tgaatatagg ggtgaacagc ataaaacctg
1201 tatgctcaat gccacatcaa aattcatgga gttctaccaa gatgtaaagg actggtggct
1261 cttcgggttc tatttctgta tgcccttggt gtgcactgcg atcttctaca ccctcatgac
1321 ttgtgagatg ttgaacagaa nnaatggcag cttgagaatt gccctcagtg aacatcttaa
1381 gcagcgtcga gaagtggcaa aaacagtttt ctgcttggtt gtaatttttg ctctttgctg
1441 gttccctctt cacttaagcc gtatattgaa gaaaactgtg tataacgaaa tggacaagaa
1501 ccgatgtgaa ttacttagtt tcttactgct catggattac atcggtatta acttggcaac
1561 catgaattca tgtataaacc ccatagctct gtattttgtg agcaagaaat ttaaaaattg
1621 tttccagtca tgcctctgct gctgctgtta ccagtccaaa agtctgatga cctcggtccc
1681 catgaacgga acaagcatcc agtggaagaa ccacgatcaa aacaaccaca acacagaccg
1741 gagcagccat aaggacagca tgaactgacc acccttagaa gcactcctcg gtactcccat
1801 aatcctctcg gagaaaaaaa tcacaaggca actgtgactc cgggaatctc ttctctgatc
1861 cttcttcctt aattcactcc cacacccaag aagaaatgct ttccaaaacc gcaaggtaga
1921 ctggtttatc cacccacaac atctacgaat cgtacttctt taattgatct aatttacata
1981 ttctgcgtgt tgtattcagc actaaaaaat ggtgggagct gggggagaat gaagactgtt
2041 aaatgaaacc agaaggatat ttactacttt tgcatgaaaa tagagctttc aagtacatgg
2101 ctagctttta tggcagttct ggtgaatgtt caatgggaac tggtcaccat gaaactttag
2161 agattaacga caagattttc tacttttttt aagtgatttt ttgtccttca gccaaacaca
2221 atatgggctc aggtcacttt tatttgaaat gtcatttggt gccagtattt tttaactgca
2281 taatagccta acatgattat ttgaacttat ttacacatag tttgaaaaaa aaaagacaaa
2341 aatagtattc aggtgagcaa ttagattagt attttccacg tcactattta tttttttaaa
2401 acacaaattc taaagctaca acaaatacta caggccctta aagcacagtc tgatgacaca
2461 tttggcagtt taatagatgt tactcaaaga attttttaag aactgtattt tattttttaa
2521 atggtgtttt attacaaggg accttgaaca tgttttgtat gttaaattca aaagtaatgc
2581 ttcaatcaga tagttctttt tcacaagttc aatactgttt ttcatgtaaa ttttgtatga
2641 aaaatcaatg tcaagtacca aaatgttaat gtatgtgtca tttaactctg cctgagactt
2701 tcagtgcact gtatatagaa gtctaaaaca cacctaagag aaaaagatcg aatttttcag
2761 atgattcgga aattttcatt caggtatttg taatagtgac atatatatgt atatacatat
2821 cacctcctat tctcttaatt tttgttaaaa tgttaactgg cagtaagtct tttttgatca
2881 ttcccttttc catataggaa acataatttt gaagtggcca gatgagttta tcatgtcagt
2941 gaaaaataat tacccacaaa tgccaccagt aacttaacga ttcttcactt cttggggttt
3001 tcagtatgaa cctaactccc caccccaaca tctccctccc acattgtcac catttcaaag
3061 ggcccacagt gacttttgct gggcattttc ccagatgttt acagactgtg agtacagcag
3121 aaaatctttt actagtgtgt gtgtgtatat atataaacaa ttgtaaattt cttttagccc
3181 atttttctag actgtctctg tggaatatat ttgtgtgtgt gatatatgca tgtgtgtgat
3241 ggtatgtatg gatttaatct aatctaataa ttgtgccccg cagttgtgcc aaagtgcata
3301 gtctgagcta aaatctaggt gattgttcat catgacaacc tgcctcagtc cattttaacc
3361 tgtagcaacc ttctgcattc ataaatcttg taatcatgtt accattacaa atgggatata
3421 agaggcagcg tgaaagcaga tgagctgtgg actagcaata tagggttttg tttggttggt
3481 tggtttgata aagcagtatt tggggtcata ttgtttcctg tgctggagca aaagtcatta
3541 cactttgaag tattatattg ttcttatcct caattcaatg tggtgatgaa attgccaggt
3601 tgtctgatat ttctttcaga cttcgccaga cagattgctg ataataaatt aggtaagata
3661 atttgttggg ccatatttta ggacaggtaa aataacatca ggttccagtt gcttgaattg
3721 caaggctaag aagtactgcc cttttgtgtg ttagcagtca aatctattat tccactggcg
3781 catcatatgc agtgatatat gcctataata taagccatag gttcacacca ttttgtttag
3841 acaattgtct ttttttcaag atgctttgtt tctttcatat gaaaaaaatg cattttataa
3901 attcagaaag tcatagattt ctgaaggcgt caacgtgcat tttatttatg gactggtaag
3961 taactgtggt ttactagcag gaatatttcc aatttctacc tttactacat cttttcaaca
4021 agtaactttg tagaaatgag ccagaagcca aggccctgag ttggcagtgg cccataagtg
4081 taaaataaaa gtttacagaa acctt
//