LOCUS S36271 2435 bp mRNA linear HUM 08-MAY-1993
DEFINITION prostaglandin G/H synthase [human, lung fibroblast, mRNA, 2435 nt].
ACCESSION S36271
VERSION S36271.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2435)
AUTHORS Diaz,A., Reginato,A.M. and Jimenez,S.A.
TITLE Alternative splicing of human prostaglandin G/H synthase mRNA and
evidence of differential regulation of the resulting transcripts by
transforming growth factor beta 1, interleukin 1 beta, and tumor
necrosis factor alpha
JOURNAL J. Biol. Chem. 267 (15), 10816-10822 (1992)
PUBMED 1587858
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 103945] from the original journal article.
FEATURES Location/Qualifiers
source 1..2435
/db_xref="H-InvDB:HIT000215562"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2435
/gene="prostaglandin G/H synthase, PGG/HS"
CDS 1..1800
/gene="prostaglandin G/H synthase, PGG/HS"
/note="PGG/HS"
/codon_start=1
/product="prostaglandin G/H synthase"
/protein_id="AAB22217.1"
/translation="MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQG
ICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFV
NATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPT
PMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPG
FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPR
GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI
LIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPD
SFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV
IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLL
EKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKL
VCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL"
BASE COUNT 504 a 666 c 645 g 620 t
ORIGIN
1 atgagccgga gtctcttgct ccggttcttg ctgttcctgc tcctgctccc gccgctcccc
61 gtcctgctcg cggacccagg ggcgcccacg ccagtgaatc cctgttgtta ctatccatgc
121 cagcaccagg gcatctgtgt ccgcttcggc cttgaccgct accagtgtga ctgcacccgc
181 acgggctatt ccggccccaa ctgcaccatc cctggcctgt ggacctggct ccggaattca
241 ctgcggccca gcccctcttt cacccacttc ctgctcactc acgggcgctg gttctgggag
301 tttgtcaatg ccaccttcat ccgagagatg ctcatgcgcc tggtactcac agtgcgctcc
361 aaccttatcc ccagtccccc cacctacaac tcagcacatg actacatcag ctgggagtct
421 ttctccaacg tgagctatta cactcgtatt ctgccctctg tgcctaaaga ttgccccaca
481 cccatgggaa ccaaagggaa gaagcagttg ccagatgccc agctcctggc ccgccgcttc
541 ctgctcagga ggaagttcat acctgacccc caaggcacca acctcatgtt tgccttcttt
601 gcacaacact tcacccacca gttcttcaaa acttctggca agatgggtcc tggcttcacc
661 aaggccttgg gccatggggt agacctcggc cacatttatg gagacaatct ggagcgtcag
721 tatcaactgc ggctctttaa ggatgggaaa ctcaagtacc aggtgctgga tggagaaatg
781 tacccgccct cggtagaaga ggcgcctgtg ttgatgcact acccccgagg catcccgccc
841 cagagccaga tggctgtggg ccaggaggtg tttgggctgc ttcctgggct catgctgtat
901 gccacgctct ggctacgtga gcacaaccgt gtgtgtgacc tgctgaaggc tgagcacccc
961 acctggggcg atgagcagct tttccagacg acccgcctca tcctcatagg ggagaccatc
1021 aagattgtca tcgaggagta cgtgcagcag ctgagtggct atttcctgca gctgaaattt
1081 gacccagagc tgctgttcgg tgtccagttc caataccgca accgcattgc catggagttc
1141 aaccatctct accactggca ccccctcatg cctgactcct tcaaggtggg ctcccaggag
1201 tacagctacg agcagttctt gttcaacacc tccatgttgg tggactatgg ggttgaggcc
1261 ctggtggatg ccttctctcg ccagattgct ggccggatcg gtgggggcag gaacatggac
1321 caccacatcc tgcatgtggc tgtggatgtc atcagggagt ctcgggagat gcggctgcag
1381 cccttcaatg agtaccgcaa gaggtttggc atgaaaccct acacctcctt ccaggagctc
1441 gtaggagaga aggagatggc agcagagttg gaggaattgt atggagacat tgatgcgttg
1501 gagttctacc ctggactgct tcttgaaaag tgccatccaa actctatctt tggggagagt
1561 atgatagaga ttggggctcc cttttccctc aagggtctcc tagggaatcc catctgttct
1621 ccggagtact ggaagccgag cacatttggc ggcgaggtgg gctttaacat tgtcaagacg
1681 gccacactga agaagctggt ctgcctcaac accaagacct gtccctacgt ttccttccgt
1741 gtgccggatg ccagtcagga tgatgggcct gctgtggagc gaccatccac agagctctga
1801 ggggcaggaa agcagcattc tggaggggag agctttgtgc ttgtcattcc agagtgctga
1861 ggccagggct gatggtctta aatgctcatt ttctggtttg gcatggtgag tgttggcgtt
1921 gacatttaga actttaagtc tcacccatta tctggaatat tgtgattctg tttattcttc
1981 cagaatgctg aactccttgt tagcccttca gattgttagg agtggttctc atttggtctg
2041 ccagaatact gggttcttag ttgacaacct agaatgtcag atttctggtt gatttgtaac
2101 acagtcattc taggatgtgg agctactgat gaaatctgct agaaagttag ggggttctta
2161 ttttgcattc cagaatcttg actttctgat tggtgattca aagtgttgtg ttccctggct
2221 gatgatccag aacagtggct cgtatcccaa atctgtcagc atctggctgt ctagaatgtg
2281 gatttgattc attttcctgt tcagtgagat atcatagaga cggagatcct aaggtccaac
2341 aagaatgcat tccctgaatc tgtgcctgca ctgagagggc aaggaagtgg ggtgttcttc
2401 ttgggacccc cactaagacc ctggtctgag gatgt
//