LOCUS S36219 2324 bp mRNA linear HUM 08-MAY-1993
DEFINITION prostaglandin G/H synthase {alternative splicing product} [human,
lung fibroblast, clone HCO-T9, mRNA, 2324 nt].
ACCESSION S36219
VERSION S36219.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2324)
AUTHORS Diaz,A., Reginato,A.M. and Jimenez,S.A.
TITLE Alternative splicing of human prostaglandin G/H synthase mRNA and
evidence of differential regulation of the resulting transcripts by
transforming growth factor beta 1, interleukin 1 beta, and tumor
necrosis factor alpha
JOURNAL J. Biol. Chem. 267 (15), 10816-10822 (1992)
PUBMED 1587858
REMARK GenBank staff at the National Library of Medicine created this
entry [NCBI gibbsq 103825] from the original journal article.
FEATURES Location/Qualifiers
source 1..2324
/db_xref="H-InvDB:HIT000215561"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="HCO-T9"
gene 1..2324
/gene="prostaglandin G/H synthase, PGG/HS"
CDS 1..1689
/gene="prostaglandin G/H synthase, PGG/HS"
/note="alternative splicing product; PGG/HS"
/codon_start=1
/product="prostaglandin G/H synthase"
/protein_id="AAB22216.1"
/translation="MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQG
ICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFV
NATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPT
PMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPG
FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPR
GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI
LIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPD
SFKIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMA
AELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWK
PSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL"
BASE COUNT 487 a 636 c 610 g 591 t
ORIGIN
1 atgagccgga gtctcttgct ccggttcttg ctgttcctgc tcctgctccc gccgctcccc
61 gtcctgctcg cggacccagg ggcgcccacg ccagtgaatc cctgttgtta ctatccatgc
121 cagcaccagg gcatctgtgt ccgcttcggc cttgaccgct accagtgtga ctgcacccgc
181 acgggctatt ccggccccaa ctgcaccatc cctggcctgt ggacctggct ccggaattca
241 ctgcggccca gcccctcttt cacccacttc ctgctcactc acgggcgctg gttctgggag
301 tttgtcaatg ccaccttcat ccgagagatg ctcatgcgcc tggtactcac agtgcgctcc
361 aaccttatcc ccagtccccc cacctacaac tcagcacatg actacatcag ctgggagtct
421 ttctccaacg tgagctatta cactcgtatt ctgccctctg tgcctaaaga ttgccccaca
481 cccatgggaa ccaaagggaa gaagcagttg ccagatgccc agctcctggc ccgccgcttc
541 ctgctcagga ggaagttcat acctgacccc caaggcacca acctcatgtt tgccttcttt
601 gcacaacact tcacccacca gttcttcaaa acttctggca agatgggtcc tggcttcacc
661 aaggccttgg gccatggggt agacctcggc cacatttatg gagacaatct ggagcgtcag
721 tatcaactgc ggctctttaa ggatgggaaa ctcaagtacc aggtgctgga tggagaaatg
781 tacccgccct cggtagaaga ggcgcctgtg ttgatgcact acccccgagg catcccgccc
841 cagagccaga tggctgtggg ccaggaggtg tttgggctgc ttcctgggct catgctgtat
901 gccacgctct ggctacgtga gcacaaccgt gtgtgtgacc tgctgaaggc tgagcacccc
961 acctggggcg atgagcagct tttccagacg acccgcctca tcctcatagg ggagaccatc
1021 aagattgtca tcgaggagta cgtgcagcag ctgagtggct atttcctgca gctgaaattt
1081 gacccagagc tgctgttcgg tgtccagttc caataccgca accgcattgc catggagttc
1141 aaccatctct accactggca ccccctcatg cctgactcct tcaagatcgg tgggggcagg
1201 aacatggacc accacatcct gcatgtggct gtggatgtca tcagggagtc tcgggagatg
1261 cggctgcagc ccttcaatga gtaccgcaag aggtttggca tgaaacccta cacctccttc
1321 caggagctcg taggagagaa ggagatggca gcagagttgg aggaattgta tggagacatt
1381 gatgcgttgg agttctaccc tggactgctt cttgaaaagt gccatccaaa ctctatcttt
1441 ggggagagta tgatagagat tggggctccc ttttccctca agggtctcct agggaatccc
1501 atctgttctc cggagtactg gaagccgagc acatttggcg gcgaggtggg ctttaacatt
1561 gtcaagacgg ccacactgaa gaagctggtc tgcctcaaca ccaagacctg tccctacgtt
1621 tccttccgtg tgccggatgc cagtcaggat gatgggcctg ctgtggagcg accatccaca
1681 gagctctgag gggcaggaaa gcagcattct ggaggggaga gctttgtgct tgtcattcca
1741 gagtgctgag gccagggctg atggtcttaa atgctcattt tctggtttgg catggtgagt
1801 gttggggttg acatttagaa ctttaagtct cacccattat ctggaatatt gtgattctgt
1861 ttattcttcc agaatgctga actccttgtt agcccttcag attgttagga gtggttctca
1921 tttggtctgc cagaatactg ggttcttagt tgacaaccta gaatgtcaga tttctggttg
1981 atttgtaaca cagtcattct aggatgtgga gctactgatg aaatctgcta gaaagttagg
2041 gggttcttat tttgcattcc agaatcttga ctttctgatt ggtgattcaa agtgttgtgt
2101 tccctggctg atgatccaga acagtggctc gtatcccaaa tctgtcagca tctggctgtc
2161 tagaatgtgg atttgattca ttttcctgtt cagtgagata tcatagagac ggagatccta
2221 aggtccaaca agaatgcatt ccctgaatct gtgcctgcac tgagagggca aggaagtggg
2281 gtgttcttct tgggaccccc actaagaccc tggtctgagg atgt
//