LOCUS HUMNC1A 2661 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens type VII collagen mRNA, partial cds.
ACCESSION M96984
VERSION M96984.1
KEYWORDS extracellular matrix adhesion protein; type VII collagen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2661)
AUTHORS Gammon,W.R., Abernethy,M.L., Padilla,K.M., Prisayanh,P.S.,
Cook,M.E., Wright,J., Briggaman,R.A. and Hunt,S.W. III.
TITLE Structural similarity to multidomain extracellular matrix adhesion
proteins supports a role for Type VII collagen in the organization
and adherence of epithelial basement membrane
JOURNAL Unpublished
FEATURES Location/Qualifiers
source 1..2661
/db_xref="H-InvDB:HIT000196946"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/germline
/tissue_lib="WISH"
CDS <1..>2661
/note="NC1 region"
/codon_start=1
/product="type VII collagen"
/protein_id="AAA36357.2"
/translation="EFRELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMAR
TDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQ
LDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATDVPGQRVRVSW
SPVPGATQYRIIWRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA
SVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLP
PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV
TITWTRVPGATGYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGV
DGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMR
HQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVV
QRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRL
SVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPL
RGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPR
GLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPL
NGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVD
EPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ
AVSGLATALCQASFTTQPRPEPCPVYCPKGQ"
repeat_region 8..135
/rpt_family="Type III homology region"
repeat_region 136..405
/rpt_family="Type III homology region"
repeat_region 406..681
/rpt_family="Type III homology region"
repeat_region 682..951
/rpt_family="Type III homology region"
repeat_region 952..1209
/rpt_family="Type III homology region"
repeat_region 1210..1491
/rpt_family="Type III homology region"
misc_feature 1252..1260
/note="putative N-linked glycosylation site"
repeat_region 1492..1758
/rpt_family="Type III homology region"
repeat_region 1759..2034
/rpt_family="Type III homology region"
misc_feature 2035..2661
/note="similar to von Willebrand factor A domain"
misc_feature 2221..2229
/note="putative N-linked glycosylation site"
misc_feature 2404..2412
/standard_name="RGD site"
BASE COUNT 464 a 801 c 865 g 531 t
ORIGIN
1 gaattccggg agctgggccc tgggcagggt tcagtgttgc tgcgtgactt ggagcctggc
61 acggactatg aggtgaccgt gagcacccta tttggccgca gtgtggggcc cgccacttcc
121 ctgatggctc gcactgacgc ttctgttgag cagaccctgc gcccggtcat cctgggcccc
181 acatccatcc tcctttcctg gaacttggtg cctgaggccc gtggctaccg gttggaatgg
241 cggcgtgaga ctggcttgga gccaccgcag aaggtggtac tgccctctga tgtgacccgc
301 taccagttgg atgggctgca gccgggcact gagtaccgcc tcacactcta cactctgctg
361 gagggccacg aggtggccac ccctgcaacc gtggttccca ctggaccaga gctgcctgtg
421 agccctgtaa cagacctgca agccaccgac gtgcccgggc agcgggtgcg agtgtcctgg
481 agcccagtcc ctggtgccac ccagtaccgc atcatttggc gcagcaccca gggggttgag
541 cggaccctgg tgcttcctgg gagtcagaca gcattcgact tggatgacgt tcaggctggg
601 cttagctaca ctgtgcgggt gtctgctcga gtgggtcccc gtgagggcag tgccagtgtc
661 ctcactgtcc gccgggagcc ggaaactcca cttgctgttc cagggctgcg ggttgtggtg
721 tcagatgcaa cgcgagtgag ggtggcctgg ggacccgtcc ctggagccag tggatttcgg
781 attagctgga gcacaggcag tggtccggag tccagccaga cactgccccc agactctact
841 gccacagaca tcacagggct gcagcctgga accacctacc aggtggctgt gtcggtactg
901 cgaggcagag aggagggccc tgctgcagtc atcgtggctc gaacggaccc actgggccca
961 gtgaggacgg tccatgtgac tcaggccagc agctcatctg tcaccattac ctggaccagg
1021 gttcctggcg ccacaggata cagggtttcc tggcactcag cccacggccc agagaaatcc
1081 cagttggttt ctggggaggc cacggtggct gagctggatg gactggagcc agatactgag
1141 tatacggtgc atgtgagggc ccatgtggct ggcgtggatg ggccccctgc ctctgtggtt
1201 gtgaggactg cccctgagcc tgtgggtcgt gtgtcgaggc tgcagatcct caatgcttcc
1261 agcgacgttc tacggatcac ctgggtaggg gtcactggag ccacagctta cagactggcc
1321 tggggccgga gtgaaggcgg ccccatgagg caccagatac tcccaggaaa cacagactct
1381 gcagagatcc ggggtctcga aggtggagtc agctactcag tgcgagtgac tgcacttgtc
1441 ggggaccgcg agggcacacc tgtctccatt gttgtcacta cgccgcctga ggctccgcca
1501 gccctgggga cgcttcacgt ggtgcagcgc ggggagcact cgctgaggct gcgctgggag
1561 ccggtgccca gagcgcaggg cttccttctg cactggcaac ctgagggtgg ccaggaacag
1621 tcccgggtcc tggggcccga gctcagcagc tatcacctgg acgggctgga gccagcgaca
1681 cagtaccgcg tgaggctgag tgtcctaggg ccggctggag aagggccctc tgcagaggtg
1741 actgcgcgca ctgagtcacc tcgtgttcca agcattgaac tacgtgtggt ggacacctcg
1801 atcgactcgg tgactttggc ctggactcca gtgtccaggg catccagtta catcctatcc
1861 tggcggccac tcagaggccc tggccaggaa gtgcctgggt ccccgcagac acttccaggg
1921 atctcaagct cccagcgggt gacagggcta gagcctggcg tctcttacat cttctccctg
1981 acgcctgtcc tggatggtgt gcggggtcct gaggcatctg tcacacagac gccagtgtgc
2041 ccccgtggcc tggcggatgt ggtgttccta ccacatgcca ctcaagacaa tgctcaccgt
2101 gcggaggcta cgaggagggt cctggagcgt ctggtgttgg cacttgggcc tcttgggcca
2161 caggcagttc aggttggcct gctgtcttac agtcatcggc cctccccact gttcccactg
2221 aatggctccc atgaccttgg cattatcttg caaaggatcc gtgacatgcc ctacatggac
2281 ccaagtggga acaacctggg cacagccgtg gtcacagctc acagatacat gttggcacca
2341 gatgctcctg ggcgccgcca gcacgtacca ggggtgatgg ttctgctagt ggatgaaccc
2401 ttgagaggtg acatattcag ccccatccgt gaggcccagg cttctgggct taatgtggtg
2461 atgttgggaa tggctggagc ggacccagag cagctgcgtc gcttggcgcc gggtatggac
2521 tctgtccaga ccttcttcgc cgtggatgat gggccaagcc tggaccaggc agtcagtggt
2581 ctggccacag ccctgtgtca ggcatccttc actactcagc cccggccaga gccctgccca
2641 gtgtattgtc caaagggcca g
//