LOCUS HUME2F 2517 bp mRNA linear HUM 27-APR-1993
DEFINITION Homo sapiens (E2F-1) pRB-binding protein mRNA, complete cds.
ACCESSION M96577
VERSION M96577.1
KEYWORDS DNA-binding protein; pRB-binding protein; transcription factor E2F.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2517)
AUTHORS Helin,K., Lees,J.A., Vidal,M., Dyson,N., Harlow,E. and Fattaey,A.
TITLE A cDNA encoding a pRB-binding protein with properties of the
transcription factor E2F
JOURNAL Cell 70 (2), 337-350 (1992)
PUBMED 1638634
COMMENT Original source text: Homo sapiens fetal brain cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2517
/db_xref="H-InvDB:HIT000196926"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Nalm 6"
/cell_type="pre B-cells"
/tissue_type="brain"
/dev_stage="fetal"
CDS 136..1449
/note="pRB-binding protein"
/codon_start=1
/product="E2F-1"
/protein_id="AAA35782.1"
/translation="MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASA
PPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLA
ESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVL
KVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQ
QLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAV
DSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPP
PSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFS
GLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF"
BASE COUNT 454 a 784 c 781 g 498 t
ORIGIN
1 ggaattccgt ggccgggact ttgcaggcag cggcggccgg gggcggagcg ggatcgagcc
61 ctcgccgagg cctgccgcca tgggcccgcg ccgccgccgc cgcctgtcac ccgggccgcg
121 cgggccgtga gcgtcatggc cttggccggg gcccctgcgg gcggcccatg cgcgccggcg
181 ctggaggccc tgctcggggc cggcgcgctg cggctgctcg actcctcgca gatcgtcatc
241 atctccgccg cgcaggacgc cagcgccccg ccggctccca ccggccccgc ggcgcccgcc
301 gccggcccct gcgaccctga cctgctgctc ttcgccacac cgcaggcgcc ccggcccaca
361 cccagtgcgc cgcggcccgc gctcggccgc ccgccggtga agcggaggct ggacctggaa
421 actgaccatc agtacctggc cgagagcagt gggccagctc ggggcagagg ccgccatcca
481 ggaaaaggtg tgaaatcccc gggggagaag tcacgctatg agacctcact gaatctgacc
541 accaagcgct tcctggagct gctgagccac tcggctgacg gtgtcgtcga cctgaactgg
601 gctgccgagg tgctgaaggt gcagaagcgg cgcatctatg acatcaccaa cgtccttgag
661 ggcatccagc tcattgccaa gaagtccaag aaccacatcc agtggctggg cagccacacc
721 acagtgggcg tcggcggacg gcttgagggg ttgacccagg acctccgaca gctgcaggag
781 agcgagcagc agctggacca cctgatgaat atctgtacta cgcagctgcg cctgctctcc
841 gaggacactg acagccagcg cctggcctac gtgacgtgtc aggaccttcg tagcattgca
901 gaccctgcag agcagatggt tatggtgatc aaagcccctc ctgagaccca gctccaagcc
961 gtggactctt cggagaactt tcagatctcc cttaagagca aacaaggccc gatcgatgtt
1021 ttcctgtgcc ctgaggagac cgtaggtggg atcagccctg ggaagacccc atcccaggag
1081 gtcacttctg aggaggagaa cagggccact gactctgcca ccatagtgtc accaccacca
1141 tcatctcccc cctcatccct caccacagat cccagccagt ctctactcag cctggagcaa
1201 gaaccgctgt tgtcccggat gggcagcctg cgggctcccg tggacgagga ccgcctgtcc
1261 ccgctggtgg cggccgactc gctcctggag catgtgcggg aggacttctc cggcctcctc
1321 cctgaggagt tcatcagcct ttccccaccc cacgaggccc tcgactacca cttcggcctc
1381 gaggagggcg agggcatcag agacctcttc gactgtgact ttggggacct cacccccctg
1441 gatttctgac agggcttgga gggaccaggg tttccagagt agctcacctt gtctctgcag
1501 ccctggagcc ccctgtccct ggccgtcctc ccagcctgtt tggaaacatt taatttatac
1561 ccctctcctc tgtctccaga agcttctagc tctggggtct ggctaccgct aggaggctga
1621 gcaagccagg aagggaagga gtctgtgtgg tgtgtatgtg catgcagcct acacccacac
1681 gtgtgtaccg ggggtgaatg tgtgtgagca tgtgtgtgtg catgtaccgg ggaatgaagg
1741 tgaacataca cctctgtgtg tgcactgcag acacgcccca gtgtgtccac atgtgtgtgc
1801 atgagtccat ctctgcgcgt gggggggctc taactgcact ttcggccctt ttgctcgtgg
1861 ggtcccacaa ggcccagggc agtgcctgct cccagaatct ggtgctctga ccaggccagg
1921 tggggaggct ttggctggct gggcgtgtag gacggtgaga gcacttctgt cttaaaggtt
1981 ttttctgatt gaagctttaa tggagcgtta tttatttatc gaggcctctt tggtgagcct
2041 ggggaatcag caaaagggga ggaggggtgt ggggttgata ccccaactcc ctctaccctt
2101 gagcaagggc aggggtccct gagctgttct tctgccccat actgaaggaa ctgaggcctg
2161 ggtgatttat ttattgggaa agtgagggag ggagacagac tgactgacag ccatgggtgg
2221 tcagatggtg gggtgggccc tctccagggg gccagttcag ggcccagctg ccccccagga
2281 tggatatgag atgggagagg tgagtggggg accttcactg atgtgggcag gaggggtggt
2341 gaaggcctcc cccagcccag accctgtggt ccctcctgca gtgtctgaag cgcctgcctc
2401 cccactgctc tgccccaccc tccaatctgc actttgattt gcttcctaac agctctgttc
2461 cctcctgctt tggttttaat aaatattttg atgacgttaa aaaaaggaat tcgatat
//