LOCUS HUMCHEMA 3175 bp mRNA linear HUM 13-JAN-1999
DEFINITION Homo sapiens putative IL-16 protein precursor, mRNA, complete cds.
ACCESSION M90391
VERSION M90391.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 252 to 3175)
AUTHORS Cruikshank,W.W., Center,D.M., Nisar,N., Wu,M., Natke,B.,
Theodore,A.C. and Kornfeld,H.
TITLE Molecular and functional analysis of a lymphocyte chemoattractant
factor: association of biologic function with CD4 expression
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91 (11), 5109-5113 (1994)
PUBMED 7910967
REFERENCE 2 (bases 252 to 3175)
AUTHORS Kornfeld,H.
TITLE Direct Submission
JOURNAL Submitted (27-APR-1993) Pulmonary Center, Boston University School
of Medicine, 80 East Concord Street, Boston, MA 02118, USA
REFERENCE 3 (bases 1 to 3175)
AUTHORS Kornfeld,H.
TITLE Direct Submission
JOURNAL Submitted (02-APR-1997) Pulmonary Center, Boston University School
of Medicine, 80 East Concord Street, Boston, MA 02118, USA
REMARK Sequence update by submitter
REFERENCE 4 (bases 1 to 3175)
AUTHORS Kornfeld,H.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-1999) Pulmonary Center, Boston University School
of Medicine, 80 East Concord Street, Boston, MA 02118, USA
REMARK Sequence update by submitter
COMMENT On Jan 13, 1999 this sequence version replaced gi:2182275.
FEATURES Location/Qualifiers
source 1..3175
/db_xref="H-InvDB:HIT000196770"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="mononuclear"
/tissue_type="peripheral blood"
/tissue_lib="lambda ZAP of K. Jacobs"
CDS 304..2199
/codon_start=1
/product="putative IL-16 protein precursor"
/protein_id="AAD04636.1"
/translation="MDYSFDTTAEDPWVRISDCIKNLFSPIMSENHGHMPLQPNASLN
EEEGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRA
SEPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQR
LSLQPSSGEAAKPLGKHEEGRFSGLLGRGAAPTLVPQQPEQVLSSGSPAASEARDPGV
SESPPPGRQPNQKTFPPGPDPLLRLLSTQAEESQGPVLKMPSQRARSFPLTRSQSCET
KLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKAGASPTSSSNEDSAAN
GSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEELKKL
IEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLAS
QEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSS
TDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIF
KGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKE
TTAAGDS"
regulatory 1694..1699
/regulatory_class="polyA_signal_sequence"
regulatory 2377..2382
/regulatory_class="polyA_signal_sequence"
BASE COUNT 851 a 874 c 795 g 655 t
ORIGIN
1 tgcttaaaaa aacacaacag gattttcgaa gaatcctttc ttagaaaaca aacaaaaaaa
61 ccaaacaaaa acgtactttc tccccactag tttacaccac aggaagcgag agagctgctg
121 ccactgctgc taccacagga agacacagca gggagaagcc ctagtgcctc tgccggctgc
181 ccaggacctg gtatcggccc acagaccaag tcctccacag agggcgagcc agggtggaga
241 agagccagcc cagtgaccca aacatccccg ataaaacacc cactgcttaa gaggcaggct
301 cggatggact atagctttga taccacagcc gaagaccctt gggttaggat ttctgactgc
361 atcaaaaact tatttagccc catcatgagt gagaaccatg gccacatgcc tctacagccc
421 aatgccagcc tgaatgaaga agaagggaca cagggccacc cagatgggac cccaccaaag
481 ctggacaccg ccaatggcac tcccaaagtt tacaagtcag cagacagcag cactgtgaag
541 aaaggtcctc ctgtggctcc caagccagcc tggtttcgcc aaagcttgaa aggtttgagg
601 aatcgtgctt cagagccaag agggctccct gatcctgcct tgtccaccca gccagcacct
661 gcttccaggg agcacctagg atcacacatc cgggcctcct cctcctcctc ctccatcagg
721 cagagaatca gctcctttga aacctttggc tcctctcaac tgcctgacaa aggagcccag
781 agactgagcc tccagccctc ctctggggag gcagcaaaac ctcttgggaa gcatgaggaa
841 ggacggtttt ctggactctt ggggcgaggg gctgcaccca ctcttgtgcc ccagcagcct
901 gagcaagtac tgtcctcggg gtcccctgca gcctccgagg ccagagaccc aggtgtgtct
961 gagtcccctc ccccagggcg gcagcccaat cagaaaactt tcccccctgg cccggacccg
1021 ctcctaaggc tgctgtcaac acaggctgag gaatctcaag gcccagtgct caagatgcct
1081 agccagcgag cacggagctt ccccctgacc aggtcccagt cctgtgagac gaagctactt
1141 gacgaaaaga ccagcaaact ctattctatc agcagccaag tgtcatcggc tgtcatgaaa
1201 tccttgctgt gccttccatc ttctatctcc tgtgcccaga ctccctgcat ccccaaggca
1261 ggggcatctc caacatcatc atccaacgaa gactcagctg caaatggttc tgctgaaaca
1321 tctgccttgg acacggggtt ctcgctcaac ctttcagagc tgagagaata tacagagggt
1381 ctcacggaag ccaaggaaga cgatgatggg gaccacagtt cccttcagtc tggtcagtcc
1441 gttatctccc tgctgagctc agaagaatta aaaaaactca tcgaggaggt gaaggttctg
1501 gatgaagcaa cattaaagca attagacggc atccatgtca ccatcttaca caaggaggaa
1561 ggtgctggtc ttgggttcag cttggcagga ggagcagatc tagaaaacaa ggtgattacg
1621 gttcacagag tgtttccaaa tgggctggcc tcccaggaag ggactattca gaagggcaat
1681 gaggttcttt ccatcaacgg caagtctctc aaggggacca cgcaccatga tgccttggcc
1741 atcctccgcc aagctcgaga gcccaggcaa gctgtgattg tcacaaggaa gctgactcca
1801 gaggccatgc ccgacctcaa ctcctccact gactctgcag cctcagcctc tgcagccagt
1861 gatgtttctg tagaatctac agcagaggcc acagtctgca cggtgacact ggagaagatg
1921 tcggcagggc tgggcttcag cctggaagga gggaagggct ccctacacgg agacaagcct
1981 ctcaccatta acaggatttt caaaggagca gcctcagaac aaagtgagac agtccagcct
2041 ggagatgaaa tcttgcagct gggtggcact gccatgcagg gcctcacacg gtttgaagcc
2101 tggaacatca tcaaggcact gcctgatgga cctgtcacga ttgtcatcag gagaaaaagc
2161 ctccagtcca aggaaaccac agctgctgga gactcctagg caggacatgc tgaagccaaa
2221 gccaataaca cacagctaac acacagctcc cataaccgct gattctcagg gtctctgctg
2281 ccgccccacc cagatggggg aaagcacagg tgggcttccc agtggctgct gcccaggccc
2341 agaccttcta ggacgccacc cagcaaaagg ttgttcctaa aataagggca gagtcacact
2401 ggggcagctg atacaaattg cagactgtgt aaaaagagag cttaatgata atattgtggt
2461 gccacaaata aaatggattt attagaattc catatgacat tcatgcctgg cttcgcaaaa
2521 tgtttcaagt actgtaactg tgtcatgatt cacccccaaa cagtgacatt tatttttctc
2581 atgaatctgc aatgtgggca gagattggaa tgggcagctc atctctgtcc cacttggcat
2641 cagctggcgt catgcaaagt catgcaaagg ctgggaccac ctgagatcat tcactcatac
2701 atctggccgt tgatgttggc tgggaactca cctggggctg ctggcctgaa tgcttatagg
2761 tggcctctcc ttgtggcctg ggctcctcac aacatggtgt ctggattccc aggatgagca
2821 tcccaggatc gcaagagcca cgtagaagct gcatcttgtt tatacctttg ccttggaagt
2881 tgcatggcat cacctccacc atactccatc agttagagct gacacaaacc tgcctgggtt
2941 taaggggaga ggaaatattg ctggggtcat ttatgaaaaa tacagtttgt cacatgaaac
3001 atttgcaaaa ttgtttttgg ttggattgga gaagtaatcc tagggaaggg tggtggagcc
3061 agtaaataga ggagtacagg tgaagcacca agctcaaagc gtggacaggt gtgccgacag
3121 aaggaaccag cgtgtatatg agggtatcaa ataaaattgc tactacttac ctacc
//