LOCUS HUMAKAP79A 2618 bp mRNA linear HUM 31-DEC-1994
DEFINITION Human cAMP-dpendent protein kinase (AKAP 79) mRNA, complete cds.
ACCESSION M90359
VERSION M90359.1
KEYWORDS anchoring protein; cAMP dependent; protein kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2618)
AUTHORS Carr,D.W., Stofko-Hahn,R.E., Fraser,I.D., Bishop,S.M., Acott,T.S.,
Brennan,R.G. and Scott,J.D.
TITLE Interaction of the regulatory subunit (RII) of cAMP-dependent
protein kinase with RII-anchoring proteins occurs through an
amphipathic helix binding motif
JOURNAL J. Biol. Chem. 266 (22), 14188-14192 (1991)
PUBMED 1860836
REFERENCE 2 (bases 1 to 2618)
AUTHORS Hirsch,A.H., Glantz,S.B., Li,Y., You,Y. and Rubin,C.S.
TITLE Cloning and expression of an intron-less gene for AKAP 75, an
anchor protein for the regulatory subunit of cAMP-dependent protein
kinase II beta
JOURNAL J. Biol. Chem. 267 (4), 2131-2134 (1992)
PUBMED 1733921
REFERENCE 3 (sites)
AUTHORS Carr,D.W., Hausken,Z.E., Fraser,I.D., Stofko-Hahn,R.E. and
Scott,J.D.
TITLE Association of the type II cAMP-dependent protein kinase with a
human thyroid RII-anchoring protein. Cloning and characterization
of the RII-binding domain
JOURNAL J. Biol. Chem. 267 (19), 13376-13382 (1992)
PUBMED 1618839
REFERENCE 4 (bases 1 to 2618)
AUTHORS Carr,D.W., Stofko-Hahn,R.E., Fraser,I.D., Cone,R.D. and Scott,J.D.
TITLE Localization of the cAMP-dependent protein kinase to the
postsynaptic densities by A-kinase anchoring proteins.
Characterization of AKAP 79
JOURNAL J. Biol. Chem. 267 (24), 16816-16823 (1992)
PUBMED 1512224
COMMENT Original source text: Homo sapiens thyroid gland cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2618
/db_xref="H-InvDB:HIT000196767"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="thyroid gland"
gene 1..2618
/gene="AKAP 79"
5'UTR 1..1297
/gene="AKAP 79"
CDS 1298..2581
/gene="AKAP 79"
/codon_start=1
/product="protein kinase"
/protein_id="AAA58363.1"
/translation="METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAA
KALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLE
GEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEI
LDIQTQTPLNDQATKAKSTQDLSEGISQKDGDEVCESNVSNSITSGEKVISVELGLDN
GHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQI
VEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKR
MEPIAIIITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSEQYETLL
IETASSLVKNAIQLSIEQLVNEMASDDNKINNLLQ"
3'UTR 2582..2618
/gene="AKAP 79"
BASE COUNT 950 a 476 c 504 g 688 t
ORIGIN
1 gaattccttt ttttttacta atgaaacact gcagattagt atccccaaac aattcatttt
61 ctgacgaaac tcttaaagcc cagtttcaga acataagctt taagcaacaa gcaatcttgt
121 gttaatctga gctctgttac agctctgccg taatctcagc caaattgctt catctgtacg
181 tggtgatacc accatctttg taatattgtg gtgaggatta gagatgtatg taaaagtgca
241 tgcactgcct aatacccaag aattgctcaa taaatgtcag ctattactac tcttactgac
301 ttccaactat gtgcagatta tggtggaaac atgtgataca gcagatacag tacttaaatg
361 aaaatgtcaa aattgtacaa ctaatttaag agtgggaaat gacagtaatg ctaaattttc
421 ctaagaatat gtatgaaaaa tagcacttcc ttgatggaac atacattttt agaacagaaa
481 ccttatgtta taatggtaaa actagagagt caaagtctct agttctaact ctggctatga
541 ccttatctag ttgcatggct tttgacaaga caactgctcc cctctggagt tcagttttgt
601 catctggctg gatttgagta atctcaaata atctctaaag tcctttgcag ctttaaatta
661 tctattgagt gtgataaaga ttacatcagc ttgcttttca tcctgcactt catttttggt
721 tcttgttgtt tgcttaactt gcactttaga gtcataagca attcacacag acaacacaac
781 taaagaactg ataatatcag acttgcaggg taatccaaaa tgaagtttca acaaggagga
841 taaaacaaaa tagaatcaca ctgaactctt taatagggcc aaagtaaacc ccaatgttta
901 ttctccagtc atttcattaa gttattatat ggaaaatatg cctggtagaa tcttatacat
961 tcactgaaat agtctccaca gaaaataata ggctcatagt gaaataaaat accactttct
1021 tttctctcat caggttgatc tttaaataaa gcaaaaattt atccaaagaa gggctttcat
1081 caagaaatta aagagagaaa ttacaagcca tagagaaact gggcatttct atactagaga
1141 aaccacctaa aacaactgta tggagtaaga tgaaaggtac tgaatatgcc tggaagaaat
1201 tttacctagt gtgacatttt tgctcatctt tttgtcacaa aaggctgcta aggaagagag
1261 aatacagttt tctagagaat aagagtgcag tgtaaaaatg gaaaccacaa tttcagaaat
1321 tcatgtagaa aacaaggatg agaagagatc agcagaaggt agtcctgggg ctgaaaggca
1381 gaaggaaaag gcatccatgc tttgcttcaa gagaagaaag aaagcagcca aagcactgaa
1441 gcccaaagct ggctctgaag ctgctgatgt ggcaaggaag tgtccacaag aagcaggagc
1501 ttctgatcag ccagagccca cacggggggc ctgggcctca ctcaaacgtc ttgtaacacg
1561 caggaaaagg tcagagtctt caaagcagca aaagccattg gagggtgaaa tgcaacctgc
1621 aataaatgct gaggatgctg atctttctaa gaaaaaggca aaatctagac ttaagattcc
1681 ctgcataaaa ttcccaagag ggccaaaaag gagtaatcat tccaaaatta tagaagactc
1741 agactgcagc atcaaagtcc aggaagaagc tgaaattttg gatatacaaa cacagacccc
1801 attgaatgat caggcaacaa aggctaagtc aacccaggat ctaagtgaag gcatctcaca
1861 gaaagatggt gatgaggtct gtgaatcaaa tgtgagcaat agcataactt ctggagagaa
1921 agtgatttca gtagaacttg gattagataa tgggcattct gctattcaaa cgggaactct
1981 aatccttgaa gaaattgaaa cgatcaagga aaaacaagat gttcaacccc agcaagcaag
2041 cccacttgaa acttcagaaa cagaccatca gcagccagta ctttctgatg ttcctccttt
2101 acctgcaatt ccagatcaac aaattgtgga agaagccagt aacagtaccc tagaaagtgc
2161 accaaatgga aaagactatg aaagtacaga gattgtagct gaagaaacta agccaaaaga
2221 tactgaattg agccaagaat cagattttaa agaaaatggg atcactgaag agaaatccaa
2281 atcagaagaa agcaaaagaa tggagccaat tgctattatt attacagaca ctgaaatcag
2341 tgaatttgat gttacaaaat ctaaaaatgt ccctaagcaa ttcttaattt cagctgaaaa
2401 tgagcaagta ggggtttttg ctaatgataa tggttttgag gatagaactt cagaacaata
2461 tgaaacactc ttaattgaaa cagcctcttc tctagtcaag aatgctattc agttgtcaat
2521 agaacagctg gttaatgaaa tggcctctga tgataataaa ataaacaatc ttctacagtg
2581 acttactctc cagagtcacg gcagaaaaaa aggaattc
//