LOCUS HUMIFNRTF 1584 bp mRNA linear HUM 01-JAN-1995
DEFINITION Human IFN-responsive transcription factor subunit mRNA, complete
cds.
ACCESSION M87503
VERSION M87503.1
KEYWORDS DNA-binding protein; IFN-alpha responsive transcription factor;
ISGF3-gamma protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1584)
AUTHORS Veals,S.A., Schindler,C., Leonard,D., Fu,X.Y., Aebersold,R.,
Darnell,J.E. Jr. and Levy,D.E.
TITLE Subunit of an alpha-interferon-responsive transcription factor is
related to interferon regulatory factor and Myb families of
DNA-binding proteins
JOURNAL Mol. Cell. Biol. 12 (8), 3315-3324 (1992)
PUBMED 1630447
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1584
/db_xref="H-InvDB:HIT000196668"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..1584
/gene="ISGF3-gamma"
CDS 35..1216
/gene="ISGF3-gamma"
/codon_start=1
/product="IFN-alpha responsive transcription factor"
/protein_id="AAA58687.1"
/translation="MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKH
AGKQDFREDQDAAFFKAWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGR
MDVAEPYKVYQLLPPGIVSGQPGTQKVPSKRQHSSVSSERKEEEDAMQNCTLSPSVLQ
DSLNNEEEGASGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDY
SLLLTFIYNGRVVGEAQVQSLDCRLVAEPSGSESSMEQVLFPKPGPLEPTQRLLSQLE
RGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVR
YFQGLGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAILSL
V"
regulatory 1563..1568
/regulatory_class="polyA_signal_sequence"
/gene="ISGF3-gamma"
polyA_site 1584
/gene="ISGF3-gamma"
BASE COUNT 364 a 434 c 428 g 358 t
ORIGIN
1 gatcagaggg cgatcagctg gacagcaact caggatggca tcaggcaggg cacgctgcac
61 ccgaaaactc cggaactggg tggtggagca agtggagagt gggcagtttc ccggagtgtg
121 ctgggatgat acagctaaga ccatgttccg gattccctgg aaacatgcag gcaagcagga
181 cttccgggag gaccaggatg ctgccttctt caaggcctgg gcaatattta agggaaagta
241 taaggagggg gacacaggag gtccagctgt ctggaagact cgcctgcgct gtgcactcaa
301 caagagttct gaatttaagg aggttcctga gaggggccgc atggatgttg ctgagcccta
361 caaggtgtat cagttgctgc caccaggaat cgtctctggc cagccaggga ctcagaaagt
421 accatcaaag cgacagcaca gttctgtgtc ctctgagagg aaggaggaag aggatgccat
481 gcagaactgc acactcagtc cctctgtgct ccaggactcc ctcaataatg aggaggaggg
541 ggccagtggg ggagcagtcc attcagacat tgggagcagc agcagcagca gcagccctga
601 gccacaggaa gttacagaca caactgaggc cccctttcaa ggggatcaga ggtccctgga
661 gtttctgctt cctccagagc cagactactc actgctgctc accttcatct acaacgggcg
721 cgtggtgggc gaggcccagg tgcaaagcct ggattgccgc cttgtggctg agccctcagg
781 ctctgagagc agcatggagc aggtgctgtt ccccaagcct ggcccactgg agcccacgca
841 gcgcctgctg agccagcttg agaggggcat cctagtggcc agcaaccccc gaggcctctt
901 cgtgcagcgc ctttgcccca tccccatctc ctggaatgca ccccaggctc cacctgggcc
961 aggcccgcat ctgctgccca gcaacgagtg cgtggagctc ttcagaaccg cctacttctg
1021 cagagacttg gtcaggtact ttcagggcct gggcccccca ccgaagttcc aggtaacact
1081 gaatttctgg gaagagagcc atggctccag ccatactcca cagaatctta tcacagtgaa
1141 gatggagcag gcctttgccc gatacttgct ggagcagact ccagagcagc aggcagccat
1201 tctgtccctg gtgtagagcc tgggggaccc atcttccacc tcacctcttt gttcttcctg
1261 tctcctttga agtagactca ttcttcacac gattgacctg tcctctttgt gataattctc
1321 agtagttgtc cgtgataatc gtgtcctgaa aatcctcgca cacactggct ggtggagaac
1381 tcaaggctaa ttttttatcc tttttttttt tttatttttg agatatacgc cctctttcat
1441 ctgtaaggga ctaggaaatt ccaaatggtg tgaacccagg gggcctttcc ctcttccctg
1501 acctcccaac tctaaagcca agcactttat atttttctct tagatattca ctaaggactt
1561 aaaataaaat ttttttgaaa gagg
//