LOCUS HUMIGFACID 2125 bp mRNA linear HUM 27-APR-1993
DEFINITION Human IGF binding protein complex acid-labile subunit a mRNA,
complete cds.
ACCESSION M86826
VERSION M86826.1
KEYWORDS acid-labile subunit; insulin-like growth factor binding protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2125)
AUTHORS Leong,S.R., Baxter,R.C., Camerato,T., Dai,J. and Wood,W.I.
TITLE Structure and functional expression of the acid-labile subunit of
the insulin-like growth factor-binding protein complex
JOURNAL Mol. Endocrinol. 6 (6), 870-876 (1992)
PUBMED 1379671
COMMENT Original source text: Homo sapiens adult liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2125
/db_xref="H-InvDB:HIT000196646"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
/dev_stage="adult"
CDS 57..1874
/note="acid-labile subunits a"
/codon_start=1
/product="insulin-like growth factor binding protein
complex"
/protein_id="AAA36047.1"
/translation="MALRKGGLALALLLLSWVALGPRSLEGADPGTPGEAEGPACPAA
CVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGF
LNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR
LEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLA
ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHN
RVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF
EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH
LEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP
HRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRL
RYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAIC
EGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAPC"
mat_peptide 138..1871
/product="insulin-like growth factor binding protein
complex"
/experiment="experimental evidence, no additional details
recorded"
/note="acid-labile subunits a"
BASE COUNT 389 a 752 c 657 g 327 t
ORIGIN
1 ggcacagcag acgtaccctc cctcgctgcc tgcctgcggc ctgccctgca tgcaggatgg
61 ccctgaggaa aggaggcctg gccctggcgc tgctgctgct gtcctgggtg gcactgggcc
121 cccgcagcct ggagggagca gaccccggaa cgccggggga agccgagggc ccagcgtgcc
181 cggccgcctg tgtctgcagc tacgatgacg acgcggatga gctcagcgtc ttctgcagct
241 ccaggaacct cacgcgcctg cctgacggag tcccgggcgg cacccaagcc ctgtggctgg
301 acggcaacaa cctctcgtcc gtccccccgg cagccttcca gaacctctcc agcctgggct
361 tcctcaacct gcagggcggc cagctgggca gcctggagcc acaggcgctg ctgggcctag
421 agaacctgtg ccacctgcac ctggagcgga accagctgcg cagcctggca ctcggcacgt
481 ttgcacacac gcccgcgctg gcctcgctcg gcctcagcaa caaccgtctg agcaggctgg
541 aggacgggct cttcgagggc ctcggcagcc tctgggacct caacctcggc tggaatagcc
601 tggcggtgct ccccgatgcg gcgttccgcg gcctgggcag cctgcgcgag ctggtgctgg
661 cgggcaacag gctggcctac ctgcagcccg cgctcttcag cggcctggcc gagctccggg
721 agctggacct gagcaggaac gcgctgcggg ccatcaaggc aaacgtgttc gtgcagctgc
781 cccggctcca gaaactctac ctggaccgca acctcatcgc tgccgtggcc ccgggcgcct
841 tcctgggcct gaaggcgctg cgatggctgg acctgtccca caaccgcgtg gctggcctcc
901 tggaggacac gttccccggt ctgctgggcc tgcgtgtgct gcggctgtcc cacaacgcca
961 tcgccagcct gcggccccgc accttcaagg acctgcactt cctggaggag ctgcagctgg
1021 gccacaaccg catccggcag ctggctgagc gcagctttga gggcctgggg cagcttgagg
1081 tgctcacgct agaccacaac cagctccagg aggtcaaggc gggcgctttc ctcggcctca
1141 ccaacgtggc ggtcatgaac ctctctggga actgtctccg gaaccttccg gagcaggtgt
1201 tccggggcct gggcaagctg cacagcctgc acctggaggg cagctgcctg ggacgcatcc
1261 gcccgcacac cttcaccggc ctctcggggc tccgccgact cttcctcaag gacaacggcc
1321 tcgtgggcat tgaggagcag agcctgtggg ggctggcgga gctgctggag ctcgacctga
1381 cctccaacca gctcacgcac ctgccccacc gcctcttcca gggcctgggc aagctggagt
1441 acctgctgct ctcccgcaac cgcctggcag agctgccggc ggacgccctg ggccccctgc
1501 agcgggcctt ctggctggac gtctcgcaca accgcctgga ggcattgccc aacagcctct
1561 tggcaccact ggggcggctg cgctacctca gcctcaggaa caactcactg cggaccttca
1621 cgccgcagcc cccgggcctg gagcgcctgt ggctggaggg taacccctgg gactgtggct
1681 gccctctcaa ggcgctgcgg gacttcgccc tgcagaaccc cagtgctgtg ccccgcttcg
1741 tccaggccat ctgtgagggg gacgattgcc agccgcccgc gtacacctac aacaacatca
1801 cctgtgccag cccgcccgag gtcgtggggc tcgacctgcg ggacctcagc gaggcccact
1861 ttgctccctg ctgaccaggt ccccggactc aagccccgga ctcaggcccc cacctggctc
1921 accttgtgct ggggacaggt cctcagtgtc ctcaggggcc tgcccagtgc acttgctgga
1981 agacgcaagg gcctgatggg gtggaaggca tggcggcccc cccagctgtc atcaattaaa
2041 ggcaaaggca atcgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaa
//