LOCUS HUMSEC7HOM 3311 bp mRNA linear HUM 03-AUG-1993
DEFINITION Human homologue of yeast sec7 mRNA, complete cds.
ACCESSION M85169
VERSION M85169.1
KEYWORDS homologous region.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3311)
AUTHORS Liu,L. and Pohajdak,B.
TITLE Cloning and sequencing of a human cDNA from cytolytic NK/T cells
with homology to yeast SEC7
JOURNAL Biochim. Biophys. Acta 1132 (1), 75-78 (1992)
PUBMED 1511013
COMMENT Original source text: Homo sapiens (library: NK subtracted from
Jurkat) cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3311
/db_xref="H-InvDB:HIT000196609"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="cytolytic NK/T"
/tissue_lib="NK subtracted from Jurkat"
CDS 70..1266
/note="yeast sec7 gene homologue"
/codon_start=1
/protein_id="AAA36602.1"
/translation="MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEV
ANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLY
KGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQK
IDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMN
RGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVK
TWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQ
VIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKV
SSTKRH"
misc_feature 108
/function="N-linked glycosylation site"
misc_feature 197
/function="N-linked glycosylation site"
misc_feature 309
/function="N-linked glycosylation site"
misc_feature 351
/function="N-linked glycosylation site"
misc_feature 1234..1260
/function="PKC site"
regulatory 3278
/regulatory_class="polyA_signal_sequence"
polyA_site 3301
BASE COUNT 784 a 820 c 953 g 754 t
ORIGIN
1 gcgagcgggg gcgcgggtgg cgcggcggga cgcgagcggc gagccggagc gcgagcccgc
61 tcccgcacca tggaggagga cgacagctac gttcccagtg acctgacagc agaggagcgt
121 caagaactgg agaacatccg acggagaaaa caggagctgc tggctgacat tcagaggctg
181 aaggatgaga tagcagaagt agctaatgaa attgaaaacc tgggatccac agaggaaagg
241 aaaaacatgc agaggaacaa acaggtagcc atgggcagga aaaaatttaa tatggaccct
301 aaaaagggga tccagttctt aatagagaac gacctcctga agaacacttg tgaagacatt
361 gcccagttct tatataaagg cgaagggctc aacaagacag ccatcggcga ctacctaggg
421 gagagagatg agtttaatat ccaggttctt catgcatttg tggagctgca tgagttcact
481 gatcttaatc tcgtccaggc actacggcag ttcctgtgga gcttccggct acccggagag
541 gcccagaaga tcgaccggat gatggaggcg tttgcccagc gatattgtca gtgcaataat
601 ggcgtgttcc agtccacgga tacttgttac gtcctctcct ttgccatcat catgttgaac
661 accagtctgc acaaccccaa tgtcaaagat aagcccactg tggagaggtt cattgccatg
721 aaccgaggca tcaatgatgg gggagacctg ccggaggagc tcctccggaa tctctatgag
781 agcataaaaa atgaaccctt taaaatccca gaagacgacg ggaatgacct cactcacact
841 ttcttcaatc cagaccgaga aggctggcta ttgaaactcg gaggtggcag ggtaaagact
901 tggaagagac gctggttcat tctgactgac aactgccttt actactttga gtataccacg
961 gataaggagc cccgtggaat catcccttta gagaatctga gtatccggga agtggaggac
1021 tccaaaaaac caaactgctt tgagctttat atccccgaca ataaagacca agttatcaag
1081 gcctgcaaga ccgaggctga cgggcgggtg gtggagggga accacactgt ttaccggatc
1141 tcagctccga cgcccgagga gaaggaggag tggattaagt gcattaaagc agccatcagc
1201 agggaccctt tctacgaaat gctcgcagca cggaaaaaga aggtctcctc cacgaagcga
1261 cactgagcgt gcagccaagg gcgttggtct gcgggggcct tggagctcct gctcttctcc
1321 cgcacctcca tggatgcact gctgccgagc agagcgtcct ctgccaggcc ccgccctgga
1381 ttcctagaga ctagcttcag cttttgctat tttttttaag tgggagaagg gtgggcagtt
1441 atcactgggg aagagaggac cggccacctg tccagcatgg gctccagagc cttcctctct
1501 cacagggcag agctcttgtc ggcagggcag cctcctggcc agtttctctg ctcagtgttc
1561 tggtagcaga gctcagagcc aactgtttac ctcttggttg tccccgtgaa gaagccttca
1621 aaccctgcac cataaataca tgtgtccata tattattata tgttaagaga aaaaggtgga
1681 aaggaagaga agccacatac tataaagatc tatttttttt ttttaagaga gaacgtaggg
1741 ctgttcaggt gcattctgcc ctggctgcgc tggggagctt ctccctggag aagagcacct
1801 ggggctgcgg ccaaggggca tcagcctggg cccgcggcag ggcctggcct gcctctcctg
1861 tgctgtggga gctcgctgcc tggtgcttgt cttggcgaga tggacaggtg aggtcgagga
1921 cgcagagggc agaggcccag tggagcctca gacggcacag tcagagtcgg gggcctgcct
1981 ggccggggtc gcagtcggca gcagcgtgca gtccggcatc tcccgcggat gcttttccat
2041 cccaagtgcc tgcggagccc gaggagagga gagagctgac tggacgctta cgttattttc
2101 ctccttcaga atccaagttc ttgttgggct ttaaagtaga aagtcagcat tttccttgag
2161 ctaaatacct aataaccaaa actgtgagga aggttatcgg gacagaggtt ccggataacc
2221 tgtttcattt tgggttttct tcctcttccc cagactccag tcctcgttct agaggaagga
2281 gtaggacttc cccgatcccc gtagcttcag ctttttctgc ctcaaaacca gccctaactg
2341 gactactctg gatgcatttt gtggtgggcc ccctagaggg aagatgggcc tttatctgct
2401 ccgtggggtg cactggagtg aggggggtgg ccgggctgcc tctcgcatct ctgtcttccc
2461 ctgcaggcgc tgtgtgagct ggccctgccc ctcctcatta cagtatgaag ggagccgtga
2521 cacgcagcat tttcctgccg ttctctcagg gactctcagg gcagctcctg ccactccgcc
2581 agggccagca tgccagtcca ggcagagcag gtggctggct gtctggccgt ctcgccccgc
2641 ccctccacag gaccctggac cagggcggtg cagggcgcag ccccgaggag gcaggtggag
2701 gagctgcggg ttttcacagg gccgcgtcgc cacggctcct ctgatccttt agggttggcg
2761 agcatctctg gaaatagctt ttgcagagga gtggtgggag gaatagaggg ggacagtctg
2821 tcacctccct ccccgccact ttgtgtagat cctacctgga gggaatggct ttaggcactt
2881 ttgtgccaga gcttgtgagg gtgacagaag agggtccagg ctggaaacct gaactttctg
2941 ggtgggagaa ccaggtggtg cctgccgagg tctgggcgtg tttgggccgg tgctggagcc
3001 tgtccagctg gcccgggccc tggcctggtt ctcaagtgtt tcctagacag agaggcacct
3061 gggtcagtat tagtctattt atcagaggtg taaataatct atgtatagtt tttctccttt
3121 tagattattt tgtatttgtt taaaagaagt tttgtcaaaa tacaaaaata taaagaaatg
3181 actgaaagtt gttgacaggg tttttaagaa ataattattc taattgtttt tgtttgtttg
3241 tttttgcctt gtaaactagc gccaaggaac tgcagcaaat aaactccaac tctgcccaag
3301 caaaaaaaaa a
//