LOCUS HUMMGDBEA 7180 bp mRNA linear HUM 21-JAN-1997
DEFINITION Human glycogen debranching enzyme mRNA, complete cds.
ACCESSION M85168
VERSION M85168.1
KEYWORDS glycogen debranching enzyme.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7180)
AUTHORS Yang,B.Z., Ding,J.H., Enghild,J.J., Bao,Y. and Chen,Y.T.
TITLE Molecular cloning and nucleotide sequence of cDNA encoding human
muscle glycogen debranching enzyme
JOURNAL J. Biol. Chem. 267 (13), 9294-9299 (1992)
PUBMED 1374391
REFERENCE 2 (bases 1 to 7180)
AUTHORS Dawson,T.
TITLE Direct Submission
JOURNAL Submitted (07-DEC-1996) Pediatrics, Duke University Medical Center,
Durham, NC 27710, USA
COMMENT On Jan 21, 1997 this sequence version replaced gi:187576.
FEATURES Location/Qualifiers
source 1..7180
/db_xref="H-InvDB:HIT000196608"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="muscle"
CDS 265..4812
/EC_number="2.4.1.25"
/EC_number="3.2.1.33"
/codon_start=1
/product="glycogen debranching enzyme"
/protein_id="AAB41040.1"
/translation="MSLLTCAFYLGYELQFRLGPTLQGKAVTVYTNYPFPGETFNREK
FRSLDWENPTEREDDSDKYCKLNLQQSGSFQYYFLQGNEKSGGGYIVVDPILRVGADN
HVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLAN
QLELNPDFSRPNRKYTWNDVGQLVEKLKKEWNVICITDVVYNHTAANSKWIQEHPECA
YNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIENDHHMNSIRKIIWEDIF
PKLKLWEFFQVDVNKAVEQFRRLLTQENRRVTKSDPNQHLTIIQDPEYRRFGCTVDMN
IALTTFIPHDKGPAAIEECCNWFHKRMEELNSEKHRLINYHQEQAVNCLLGNVFYERL
AGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPNKACFLMAHNGWVMGDDP
LRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRL
DNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNVFVTRLGISSLIREAMSA
YNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDITHDNECPIVHRSAYDAL
PSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNPEALPSNTGEVNFQSGII
AARCAISKLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTS
FYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSINGTPDITVEIREHIQLNES
KIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPH
FKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESEEKEDGGGCYDIPNWSAL
KYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSNRLISRSGTIAEVGKWLQ
AMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFVQNGSTFVKHLSLGSVQL
CGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFI
ALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYARYNCRDAVWWWLQCIQD
YCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVIQEAMQKHMQGIQFRERN
AGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPR
DGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKRHGKAIKVSYDEWNRKIQDNFEK
LFHVSEDPSDLNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTTE
KAGKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLW
PIGYFLRAKLYFSRLMGPETTAKTIVLVKNVLSRHYVHLERSPWKGLPELTNENAQYC
PFSCETQAWSIATILETLYDL"
BASE COUNT 2331 a 1178 c 1409 g 2262 t
ORIGIN
1 tgtataagaa tttgcacatc ccaagttgct atgtgaatag gaatgtacgt ttccagggga
61 aggagaaaga gacattacag agcagacagc tctatgatgt ttactatact tgctaaaatg
121 tgaaattcag ctaaattgga atacaaagta gtgccaaaac agcattaggt ttgcggagtt
181 attttaaaca taattgaaaa atcaaggttt tttaatactt taaataaaac atctgttttt
241 caatgtggta atttaagtcc tacgatgagt ttattaacat gtgcttttta tttagggtat
301 gagctacagt tccgattagg cccaacttta cagggaaaag cagttaccgt gtatacaaat
361 tacccatttc ctggagaaac atttaataga gaaaaattcc gttctctgga ttgggaaaat
421 ccaacagaaa gagaagatga ttctgataaa tactgtaaac ttaatctgca acaatctggt
481 tcatttcagt attatttcct tcaaggaaat gagaaaagtg gtggaggtta catagttgtg
541 gaccccattt tacgtgttgg tgctgataat catgtgctac ccttggactg tgttactctt
601 cagacatttt tagctaagtg tttgggacct tttgatgaat gggaaagcag acttagggtt
661 gcaaaagaat caggctacaa catgattcat tttaccccat tgcagactct tggactatct
721 aggtcatgct actcccttgc caatcagtta gaattaaatc ctgacttttc aagacctaat
781 agaaagtata cctggaatga tgttggacag ctagtggaaa aattaaaaaa ggaatggaat
841 gttatttgta ttactgatgt tgtctacaat catactgctg ctaatagtaa atggatccag
901 gaacatccag aatgtgccta taatcttgtg aattctccac acttaaaacc tgcctgggtc
961 ttagacagag cactttggcg tttctcctgt gatgttgcag aagggaaata caaagaaaag
1021 ggaatacctg ctttgattga aaatgatcac catatgaatt ccatccgaaa aataatttgg
1081 gaggatattt ttccaaagct taaactctgg gaatttttcc aagtagatgt caacaaagcg
1141 gttgagcaat ttagaagact tcttacacaa gaaaataggc gagtaaccaa gtctgatcca
1201 aaccaacacc ttacgattat tcaagatcct gaatacagac ggtttggctg tactgtagat
1261 atgaacattg cactaacgac tttcatacca catgacaagg ggccagcagc aattgaagaa
1321 tgctgtaatt ggtttcataa aagaatggag gaattaaatt cagagaagca tcgactcatt
1381 aactatcatc aggaacaggc agttaattgc cttttgggaa atgtgtttta tgaacgactg
1441 gctggccatg gtccaaaact aggacctgtc actagaaagc atcctttagt taccaggtat
1501 tttactttcc catttgaaga gatagacttc tccatggaag aatctatgat tcatctgcca
1561 aataaagctt gttttctgat ggcacacaat ggatgggtaa tgggagatga tcctcttcga
1621 aactttgctg aaccgggttc agaagtttac ctaaggagag aacttatttg ctggggagac
1681 agtgttaaat tacgctatgg gaataaacca gaggactgtc cttatctctg ggcacacatg
1741 aaaaaataca ctgaaataac tgcaacttat ttccagggag tacgtcttga taactgccac
1801 tcaacacctc ttcacgtagc tgagtacatg ttggatgctg ctaggaattt gcaacccaat
1861 ttatatgtag tagctgaact gttcacagga agtgaagatc tggacaatgt ctttgttact
1921 agactgggca ttagttcctt aataagagag gcaatgagtg catataatag tcatgaagag
1981 ggcagattag tttaccgata tggaggagaa cctgttggat cctttgttca gccctgtttg
2041 aggcctttaa tgccagctat tgcacatgcc ctgtttatgg atattacgca tgataatgag
2101 tgtcctattg tgcatagatc agcgtatgat gctcttccaa gtactacaat tgtttctatg
2161 gcatgttgtg ctagtggaag tacaagaggc tatgatgaat tagtgcctca tcagatttca
2221 gtggtttctg aagaacggtt ttacactaag tggaatcctg aagcattgcc ttcaaacaca
2281 ggtgaagtta atttccaaag cggcattatt gcagccaggt gtgctatcag taaacttcat
2341 caggagcttg gagccaaggg ttttattcag gtgtatgtgg atcaagttga tgaagacata
2401 gtggcagtaa caagacactc acctagcatc catcagtctg ttgtggctgt atctagaact
2461 gctttcagga atcccaagac ttcattttac agcaaggaag tgcctcaaat gtgcatccct
2521 ggcaaaattg aagaagtagt tcttgaagct agaactattg agagaaacac gaaaccttat
2581 aggaaggatg agaattcaat caatggaaca ccagatatca cagtagaaat tagagaacat
2641 attcagctta atgaaagtaa aattgttaaa caagctggag ttgccacaaa agggcccaat
2701 gaatatattc aagaaataga atttgaaaac ttgtctccag gaagtgttat tatattcaga
2761 gttagtcttg atccacatgc acaagtcgct gttggaattc ttcgaaatca tctgacacaa
2821 ttcagtcctc actttaaatc tggcagccta gctgttgaca atgcagatcc tatattaaaa
2881 attccttttg cttctcttgc ctccagatta actttggctg agctaaatca gatcctttac
2941 cgatgtgaat cagaagaaaa ggaagatggt ggagggtgct atgacatacc aaactggtca
3001 gcccttaaat atgcaggtct tcaaggttta atgtctgtat tggcagaaat aagaccaaag
3061 aatgacttgg ggcatccttt ttgtaataat ttgagatctg gagattggat gattgactat
3121 gtcagtaacc ggcttatttc acgatcagga actattgctg aagttggtaa atggttgcag
3181 gctatgttct tctacctgaa gcagatccca cgttacctta tcccatgtta ctttgatgct
3241 atattaattg gtgcatatac cactcttctg gatacagcat ggaagcagat gtcaagcttt
3301 gttcagaatg gttcaacctt tgtgaaacac ctttcattgg gttcagttca actgtgtgga
3361 gtaggaaaat tcccttccct gccaattctt tcacctgccc taatggatgt accttatagg
3421 ttaaatgaga tcacaaaaga aaaggagcaa tgttgtgttt ctctagctgc aggcttacct
3481 catttttctt ctggtatttt ccgctgctgg ggaagggata cttttattgc acttagaggt
3541 atactgctga ttactggacg ctatgtagaa gccaggaata ttattttagc atttgcgggt
3601 accctgaggc atggtctcat tcctaatcta ctgggtgaag ggatttatgc cagatacaat
3661 tgtcgggatg ctgtgtggtg gtggctgcag tgtatccagg attactgtaa aatggttcca
3721 aatggtctag acattctcaa gtgcccagtt tccagaatgt atcctacaga tgattctgct
3781 cctttgcctg ctggcacact ggatcagcca ttgtttgaag tcatacagga agcaatgcaa
3841 aaacacatgc agggcataca gttccgagaa aggaatgctg gtccccagat agatcgaaac
3901 atgaaggacg aaggttttaa tataactgca ggagttgatg aagaaacagg atttgtttat
3961 ggaggaaatc gtttcaattg tggcacatgg atggataaaa tgggagaaag tgacagagct
4021 agaaacagag gaatcccagc cacaccaaga gatgggtctg ctgtggaaat tgtgggcctg
4081 agtaaatctg ctgttcgctg gttgctggaa ttatccaaaa aaaatatttt cccttatcat
4141 gaagtcacag taaaaagaca tggaaaggct ataaaggtct catatgatga gtggaacaga
4201 aaaatacaag acaactttga aaagctattt catgtttccg aagacccttc agatttaaat
4261 gaaaagcatc caaatctggt tcacaaacgt ggcatataca aagatagtta tggagcttca
4321 agtccttggt gtgactatca gctcaggcct aattttacca tagcaatggt tgtggcccct
4381 gagctcttta ctacagaaaa agcagggaaa gctttggaga ttgcagaaaa aaaattgctt
4441 ggtccccttg gcatgaaaac tttagatcca gatgatatgg tttactgtgg aatttatgac
4501 aatgcattag acaatgacaa ctacaatctt gctaaaggtt tcaattatca ccaaggacct
4561 gagtggctgt ggcctattgg gtattttctt cgtgcaaaat tatatttttc cagattgatg
4621 ggcccggaga ctactgcaaa gactatagtt ttggttaaaa atgttctttc ccgacattat
4681 gttcatcttg agagatcccc ttggaaagga cttccagaac tgaccaatga gaatgcccag
4741 tactgtcctt tcagctgtga aacacaagcc tggtcaattg ctactattct tgagacactt
4801 tatgatttat agtttattac agatattaag tatgcaatta ctgtattata ggatgcaagg
4861 tcatcatatg taaatgctat atgcacaggc tcaagttgtt ttaaaaatct catttattat
4921 aatattgatg ctcaattagg taagattgta aaagcattga ttttttttaa tgtacagagg
4981 tagatttcaa tttgaatcag aaagaaatat cattaccaat gaaatgtgtt tgagttcagt
5041 aagaattatt caaatgccta gaaatccata gtttggaaaa taaaaatcat gtcatcttct
5101 atttgtacag aaatgaaaat aaaatatgaa aataatgaaa gaaatgaaaa gatagctttt
5161 aattgtggta tatataatct tcagtaacaa tacatactga atacgctgtg gttcattaat
5221 attaacacca cgtactatag tattcttaga atacagtgct cactgcattt aataaatatt
5281 taataaatga tgaatgatag aagtttccat ctacaatata tgttcctaaa tggagcacag
5341 atgttcaaac tatgctttca ttttttcact gatatattaa tttttgtgta atgaatgcca
5401 acagtatatt ttatatgatt tacttatgtg aggaaacatg caaagcatta ggaaatttat
5461 ttcctaaaaa cagttttgta aaattagtat tgagttctat tgagtattat aagatagctt
5521 acattttcaa aatggaaatt gtcggtcata tttctagaac tttaaagaaa aaagaatgtt
5581 atattagttt tctaaaactc aactatcttt agtcatgttc aaaaatctat tgctagatca
5641 tagtagatac tggttttcta ttaactcaaa acctacattg acaagtttaa cattgagaag
5701 aatcttaaca aaaatatgga tatgaattca gtagatatct taaattcaat aaaatcactg
5761 gaagtttttc atgataactt attttaagat gccttaaaaa tcttaaagtc acaaaaggaa
5821 aaaggttttt aacatttaca tgagttaaca ttttttcata gaacttattt cctagataga
5881 attttttact gttttttact gttttcttaa gaaaacagtt aaatcattat gcattcagtt
5941 ggaagaaagt agtggcaaga attctttcat tgctatataa tattcagtgg ctcatttata
6001 cctaataaaa taatggtatt ttaaaataat gctactttca aagtagcatt tttttagtta
6061 gtttacaggt tacataccca aaaccttaac tatgactaag aaattaaaga agaaaaccag
6121 caaactaaaa cttctgggca gcaaaaatat ataaatgctt cagatgtcaa atacccatgc
6181 ttgaaagctc gtgtaattta ctttaagatt atctgcctgc tcttcttcaa agctgacctt
6241 gctttagaaa tagttttaac tagcttagtt ttctggtttc caaaactaaa atagattaaa
6301 tcctacaaat ttaaggacag ttgtgacagt aatctgacca ctatctataa atacattgga
6361 cattggtttc caaatctccc tttctcttca gttccttcct tgttcaatat atacccttct
6421 ctaaactgtg cgggtaaaag gaatgactgt ccttgagaga accattagtt tatcaaaggt
6481 ttatgtagtt ttgttgctgt accctaactt tgatattcag ggaggtagga aaggtaacag
6541 aaaaccagca tatttaatca aagcaagaag taatcgctga cagttaaatg tgaccaaaaa
6601 aattaaaagt tcacaatttt tttaatgtag ccatttgggg ttatctctag taaggcagat
6661 acccacgttg gtaaattttt aggatattgt gttgcactag aaaactaagt ggttcatatt
6721 tctaatgagg aagattaatg aaagaacatt gttatattct gcgtggtata ttttaaagtt
6781 taagaaggca tgttaaacat tatttcctct atggtagtta aaatacagaa ttagattttt
6841 aacaggtgtc atttgactaa acgtttcggt agaatgcttc atacttgagt gatgctggat
6901 aaggtattgt atttcaacaa tggactatgc cttggttttt cactaatcaa aatcaaaatt
6961 actctttaac atgataaatg aatttaccag tttagtatgc tgtggtattt taataagttt
7021 tcaaagataa ttgggaaaac atgagactgg tcatattgat gaatattgta acatgtgaat
7081 tgtgatccat ttctgatatg tcttgaacta ctgtgtctag taggcaaatg tcattgttac
7141 ctctgtgtgt taagaaaata aaaatatttt ctaaaggtcg
//