LOCUS HUMCGMP 2500 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human cGMP-gated cation channel protein mRNA, complete cds.
ACCESSION M84741
VERSION M84741.1
KEYWORDS cGMP-gated cation channel.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2500)
AUTHORS Pittler,S.J., Lee,A.K., Altherr,M.R., Howard,T.A., Seldin,M.F.,
Hurwitz,R.L., Wasmuth,J.J. and Baehr,W.
TITLE Primary structure and chromosomal localization of human and mouse
rod photoreceptor cGMP-gated cation channel
JOURNAL J. Biol. Chem. 267 (9), 6257-6262 (1992)
PUBMED 1372902
COMMENT Original source text: Homo sapiens adult retina cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2500
/db_xref="H-InvDB:HIT000196597"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="4"
/tissue_type="retina"
/dev_stage="adult"
gene 1..2500
/gene="CNCG"
CDS 25..2097
/gene="CNCG"
/codon_start=1
/product="cGMP-gated cation channel protein"
/protein_id="AAA52010.1"
/db_xref="GDB:G00-127-557"
/translation="MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSE
DDDSAYTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIAIFNVNNSSNKDQEP
EEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEHHKKEVVVIDP
SGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVR
TRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLL
RFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVY
PDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATI
VGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICK
KGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSTFGEISILNIKGSKAGNRRTANIK
SIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLE
EKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPWS
ESGPIDST"
BASE COUNT 861 a 431 c 525 g 683 t
ORIGIN
1 tatattactt aaacaaccaa agatatgaaa ctatccatga agaacaatat tatcaataca
61 cagcagtctt ttgtaaccat gcccaatgtg attgtaccag atattgaaaa ggaaatacga
121 aggatggaaa atggagcatg cagctccttt tctgaggatg atgacagtgc ctatacatct
181 gaagaatcag agaatgaaaa ccctcatgca aggggttcct ttagttataa gtcactcaga
241 aagggaggac catcacagag ggagcagtac ctgcctggtg ccattgccat ttttaatgtg
301 aacaacagca gcaataagga ccaggaacca gaggaaaaaa agaaaaagaa aaaagaaaag
361 aagagcaagt cagatgataa aaacgaaaat aaaaacgacc cagagaagaa aaagaagaaa
421 aaggacaaag agaagaaaaa gaaagaggag aaaagcaaag ataagaaaga acaccacaag
481 aaagaagttg tggttattga tccctcggga aacacatatt acaactggct gttttgcatc
541 acattacctg ttatgtacaa ctggacaatg gttattgcca gagcatgttt tgatgaactt
601 caatctgatt acctagaata ttggctcatt ttggattacg tatcagacat agtctattta
661 atcgatatgt ttgtacgaac aaggacaggt tacctagaac aaggactgct ggtaaaggaa
721 gaacttaaac tcataaataa atataaatcc aacttgcaat ttaaacttga tgttctgtca
781 ctgataccaa ctgatttgct gtattttaag ttagggtgga actatccaga aattagatta
841 aacaggttgt tacggttctc tcgtatgttt gagttcttcc agagaacaga aacaaggaca
901 aactatccaa acatcttcag gatttccaac cttgttatgt atatcgtcat cattatccac
961 tggaatgcat gtgtgttcta ctctatttct aaagctattg gatttggaaa tgatacatgg
1021 gtctaccctg atattaatga tcctgaattt ggccgtttgg ctagaaaata cgtatacagc
1081 ctttactggt ctacactgac tttgactacc attggtgaaa caccccctcc cgtgagggat
1141 tctgagtatg tctttgtggt ggttgatttc ctaattggag tgttaatttt tgctaccatc
1201 gttggtaaca taggttctat gatttccaac atgaatgcag ccagagcaga atttcaagca
1261 agaattgatg ctatcaagca atatatgcat tttcgaaatg taagcaaaga tatggaaaag
1321 agggttatta aatggtttga ctacctgtgg accaacaaaa aaacagttga tgagaaagaa
1381 gtcttaaagt atctacctga taaactaaga gcagaaattg ccatcaacgt tcacttagac
1441 acattaaaaa aggtacgcat ttttgctgat tgtgaagctg gtctgttggt ggagttggtc
1501 ttgaaattgc aaccccaagt ctacagtcct ggagattata tttgcaagaa aggggatatc
1561 ggacgagaga tgtacattat caaggaaggc aaactcgctg tggtggcaga tgatggagtc
1621 actcagtttg tggtattgag cgatggcagc accttcggtg agatcagcat tcttaacatt
1681 aaagggagca aagctggcaa tcgaagaacg gccaatatta aaagtattgg ctactcagac
1741 ctgttctgtc tctcaaaaga tgacctcatg gaagctctaa ctgagtaccc agatgccaaa
1801 actatgctag aagaaaaagg gaagcaaatt ttaatgaaag atggtctact ggatctaaac
1861 attgcaaatg ctggcagtga tcctaaagat cttgaagaga aggttactcg aatggagggg
1921 tcagtagacc tcctgcaaac caggtttgcc cgaatcttgg ctgagtatga gtccatgcag
1981 cagaaactga aacaaagatt aaccaaggtt gagaaatttc tgaaaccgct tattgacaca
2041 gaattttcaa gtattgaggg accttggagc gaaagtgggc ccatcgactc tacatagaac
2101 cgaaaagctg gtcattaaca gggacatgcc tcatgatcct tttgatccta tgactgacat
2161 caactaaaat ttaaaagaag aggaagactc agttgggaaa tttttccatg aggaaaatgt
2221 gctttggtgc aaggtacagc ccacacctct ctgagagata ctatgattaa aaaagcttta
2281 tatctgggat ttttcacaac tgataatgtg caaagatata aactgattaa cttgtcagtg
2341 tctgtatttt ctgatttttt cacatacgct cattttatgt aatattcttc ataaaaatga
2401 ataagtagcc ctcactttca tgccatttcc attgttgagt gaagcgtatt tgaagtaact
2461 gagaattacc atgtacatca tatttgggat aacattttta
//