LOCUS HUMERK2A 1611 bp mRNA linear HUM 31-DEC-1994
DEFINITION Human extracellular signal-regulated kinase 2 mRNA, complete cds.
ACCESSION M84489
VERSION M84489.1
KEYWORDS kinase 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1611)
AUTHORS Owaki,H., Makar,R., Boulton,T.G., Cobb,M.H. and Geppert,T.D.
TITLE Extracellular signal-regulated kinases in T cells: characterization
of human ERK1 and ERK2 cDNAs
JOURNAL Biochem. Biophys. Res. Commun. 182 (3), 1416-1422 (1992)
PUBMED 1540184
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1611
/db_xref="H-InvDB:HIT000196579"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="JURKAT"
/cell_type="T CELL"
gene 1..1611
/gene="ERK2"
CDS 328..1410
/gene="ERK2"
/codon_start=1
/product="protein kinase 2"
/protein_id="AAA58459.1"
/translation="MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYD
NVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVY
IVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT
CDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL
AEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWN
RLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDME
LDDLPKEKLKELIFEETARFQPGYRS"
BASE COUNT 403 a 421 c 407 g 380 t
ORIGIN
1 acataatttc tggagccctg taccaacgtg tggccacata ttctgtcagg aaccctgtgt
61 gatcatggtc tggatctgca acacgggcca ggccaaagtc acagatcttg agatcacagg
121 tggtgttgag cagcaggcag gcaggcaatc ggtccgagtg gctgtcggct cttcagctct
181 ccgctcggcg tcttccttcc tctcccggtc agcgtcggcg gctgcaccgg cggcgggcag
241 tcctgcggga ggggcgacaa gagctgaggc gcggccgccg agcgtcgagc tcagcgcggc
301 ggaggcggcg gcggcccggc agccaacatg gcggcggcgg cggcggcggg cgcgggcccg
361 gagatggtcc gcgggcaggt gttcgacgtg gggccgcgct acaccaacct ctcgtacatc
421 ggcgagggcg cctacggcat ggtgtgctct gcttatgata atgtcaacaa agttcgagta
481 gctatcaaga aaatcagccc ctttgagcac cagacctact gccagagaac cctgagggag
541 ataaaaatct tactgcgctt cagacatgag aacatcattg gaatcaatga cattattcga
601 gcaccaacca tcgagcaaat gaaagatgta tatatagtac aggacctcat ggaaacagat
661 ctttacaagc tcttgaagac acaacacctc agcaatgacc atatctgcta ttttctctac
721 cagatcctca gagggttaaa atatatccat tcagctaacg ttctgcaccg tgacctcaag
781 ccttccaacc tgctgctcaa caccacctgt gatctcaaga tctgtgactt tggcctggcc
841 cgtgttgcag atccagacca tgatcacaca gggttcctga cagaatatgt ggccacacgt
901 tggtacaggg ctccagaaat tatgttgaat tccaagggct acaccaagtc cattgatatt
961 tggtctgtag gctgcattct ggcagaaatg ctttccaaca ggcccatctt tccagggaag
1021 cattatcttg accagctgaa tcacattttg ggtattcttg gatccccatc acaagaagac
1081 ctgaattgta taataaattt aaaagctagg aactatttgc tttctcttcc acacaaaaat
1141 aaggtgccat ggaacaggct gttcccaaat gctgactcca aagctctgga cttattggac
1201 aaaatgttga cattcaaccc acacaagagg attgaagtag aacaggctct ggcccaccca
1261 tatctggagc agtattacga cccgagtgac gagcccatcg ccgaagcacc attcaagttc
1321 gacatggaat tggatgactt gcctaaggaa aagctaaaag aactaatttt tgaagagact
1381 gctagattcc agccaggata cagatcttaa atttgtcagg acaagggctc agaggactgg
1441 acgtgctcag acatcggtgt tcttcttccc agttcttgac ccctggtcct gtctccagcc
1501 cgtcttggct tatccacttt gactcctttg agccgtttgg aggggcggtt tctggtagtt
1561 gtggctttta tgctttcaaa gaatttcttc agtccagaga attcactggc c
//