LOCUS HUMA5NICRC 1679 bp mRNA linear HUM 31-DEC-1994
DEFINITION H.sapiens nicotinic receptor alpha 5 subunit mRNA, complete cds.
ACCESSION M83712
VERSION M83712.1
KEYWORDS nicotinic receptor alpha 5 subunit.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1679)
AUTHORS Chini,B., Clementi,F., Hukovic,N. and Sher,E.
TITLE Neuronal-type alpha-bungarotoxin receptors and the alpha
5-nicotinic receptor subunit gene are expressed in neuronal and
nonneuronal human cell lines
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1572-1576 (1992)
PUBMED 1542648
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1679
/db_xref="H-InvDB:HIT000196546"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="IMR32"
/cell_type="neuroblastoma cell line"
gene 1..1679
/gene="nicotinic receptor alpha 5 subunit"
CDS 149..1555
/gene="nicotinic receptor alpha 5 subunit"
/codon_start=1
/product="nicotinic receptor alpha 5 subunit"
/protein_id="AAA58357.1"
/translation="MAARGSGPRALRLLLLVQLVAGALRSSRARRAARRGLSEPSSIA
KHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQE
WIDVKLRWNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTW
TPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEW
EIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPS
NEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFA
INIHHRSSSTHNAMAPLVRKIFLHTLPKLLSMRSHVDRYFTQKEETESGSGPKSSRNT
LEAALDSIRYITTHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPV
IYKWANILIPVHIGNANK"
sig_peptide 149..214
/gene="nicotinic receptor alpha 5 subunit"
mat_peptide 215..1552
/gene="nicotinic receptor alpha 5 subunit"
/product="nicotinic receptor alpha 5 subunit"
BASE COUNT 444 a 352 c 389 g 494 t
ORIGIN
1 gggagctgtg gcgcggagcg gcccctctgc tgcgtctgcc ctcgttttgt ctcacgactc
61 acactcagtg ctccattccc caagagttcg cgttccccgc gcggcggtcg agaggcggct
121 gcccgcggtc ccgcgcgggc gcggggcgat ggcggcgcgg gggtcagggc cccgcgcgct
181 ccgcctgctg ctcttggtcc agctggtcgc gggggcgctg cggtctagcc gggcgcggcg
241 ggcggcgcgc agaggattat ctgaaccttc ttctattgca aaacatgaag atagtttgct
301 taaggattta tttcaagact acgaaagatg ggttcgtcct gtggaacacc tgaatgacaa
361 aataaaaata aaatttggac ttgcaatatc tcaattggtg gatgtggatg agaaaaatca
421 gttaatgaca acaaacgtct ggttgaaaca ggaatggata gatgtaaaat taagatggaa
481 ccctgatgac tatggtggaa taaaagttat acgtgttcct tcagactctt cgtggacacc
541 agacatcgtt ttgtttgata atgcagatgg acgttttgaa gggaccagta cgaaaacagt
601 catcaggtac aatggcactg tcacctggac tccaccggca aactacaaaa gttcctgtac
661 catagatgtc acgtttttcc catttgacct tcagaactgt tccatgaaat ttggttcttg
721 gacttatgat ggatcacagg ttgatataat tctagaggac caagatgtag acaagagaga
781 tttttttgat aatggagaat gggagattgt gagtgcaaca gggagcaaag gaaacagaac
841 cgacagctgt tgctggtatc cgtatgtcac ttactcattt gtaatcaagc gcctgcctct
901 cttttatacc ttgttcctta taataccctg tattgggctc tcatttttaa ctgtacttgt
961 cttctatctt ccttcaaatg aaggtgaaaa gatttgtctc tgcacttcag tacttgtgtc
1021 tttgactgtc ttccttctgg ttattgaaga gatcatacca tcatcttcaa aagtcatacc
1081 tctaattgga gagtatctgg tatttaccat gatttttgtg acactgtcaa ttatggtaac
1141 cgtcttcgct atcaacattc atcatcgttc ttcctcaaca cataatgcca tggcgccttt
1201 ggtccgcaag atatttcttc acacgcttcc caaactgctt tcgatgagaa gtcatgtaga
1261 caggtacttc actcagaaag aggaaactga gagtggtagt ggaccaaaat cttctagaaa
1321 cacattggaa gctgcgctcg attctattcg ctacattaca acacacatca tgaaggaaaa
1381 tgatgtccgt gaggttgttg aagattggaa attcatagcc caggttcttg atcggatgtt
1441 tctgtggact tttcttttcg tttcaattgt tggatctctt gggctttttg ttcctgttat
1501 ttataaatgg gcaaatatat taataccagt tcatattgga aatgcaaata agtgaagcct
1561 cccaagggac tgaagtatac atttagttaa cacacatata tctgatggca cctataaaat
1621 tatgaaaatg taagttatgt gttaaattta gtgcaagctt taacagacta agttgctaa
//