LOCUS HUMMO3A 1349 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human monocyte activation antigen (Mo3) mRNA, complete cds.
ACCESSION M83246
VERSION M83246.1
KEYWORDS activation antigen; plasminogen activator receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1349)
AUTHORS Min,H.Y., Semnani,R., Mizukami,I.F., Watt,K., Todd,R.F. III and
Liu,D.Y.
TITLE cDNA for Mo3, a monocyte activation antigen, encodes the human
receptor for urokinase plasminogen activator
JOURNAL J. Immunol. 148 (11), 3636-3642 (1992)
PUBMED 1316922
COMMENT Original source text: Homo sapiens (tissue library: pCDNA1) cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..1349
/db_xref="H-InvDB:HIT000196524"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="PMN"
/cell_type="monocyte"
/tissue_lib="pCDNA1"
gene 1..1349
/gene="Mo3"
CDS 18..1025
/gene="Mo3"
/codon_start=1
/product="activation antigen"
/protein_id="AAA59862.1"
/translation="MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQD
LCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGN
SGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRP
KDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYS
CKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGD
AFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLW
T"
sig_peptide 18..83
/gene="Mo3"
mat_peptide 84..1022
/gene="Mo3"
/product="activation antigen"
BASE COUNT 317 a 388 c 353 g 291 t
ORIGIN Homo sapiens Mo3.
1 ggagctgccc tcgcgacatg ggtcacccgc cgctgctgcc gctgctgctg ctgctccaca
61 cctgcgtccc agcctcttgg ggcctgcggt gcatgcagtg taagaccaac ggggattgcc
121 gtgtggaaga gtgcgccctg ggacaggacc tctgcaggac cacgatcgtg cgcttgtggg
181 aagaaggaga agagctggag ctggtggaga aaagctgtac ccactcagag aagaccaaca
241 ggaccctgag ctatcggact ggcttgaaga tcaccagcct taccgaggtt gtgtgtgggt
301 tagacttgtg caaccagggc aactctggcc gggctgtcac ctattcccga agccgttacc
361 tcgaatgcat ttcctgtggc tcatcagaca tgagctgtga gaggggccgg caccagagcc
421 tgcagtgccg cagccctgaa gaacagtgcc tggatgtggt gacccactgg atccaggaag
481 gtgaagaagg gcgtccaaag gatgaccgcc acctccgtgg ctgtggctac cttcccggct
541 gcccgggctc caatggtttc cacaacaacg acaccttcca cttcctgaaa tgctgcaaca
601 ccaccaaatg caacgagggc ccaatcctgg agcttgaaaa tctgccgcag aatggccgcc
661 agtgttacag ctgcaagggg aacagcaccc atggatgctc ctctgaagag actttcctca
721 ttgactgccg aggccccatg aatcaatgtc tggtagccac cggcactcac gaaccgaaaa
781 accaaagcta tatggtaaga ggctgtgcaa ccgcctcaat gtgccaacat gcccacctgg
841 gtgacgcctt cagcatgaac cacattgatg tctcctgctg tactaaaagt ggctgtaacc
901 acccagacct ggatgtccag taccgcagtg gggctgctcc tcagcctggc cctgcccatc
961 tcagcctcac catcaccctg ctaatgactg ccagactgtg gggaggcact ctcctctgga
1021 cctaaacctg aaatccccct ctctgccctg gctggatccg gggacccctt tgcccttccc
1081 tcggctccca gccctacaga cttgctgtgt gacctcaggc cagtgtgccg acctctctgg
1141 gcctcagttt tcccagctat gaaaacagct atctcacaaa gttgtgtgaa gcagaagaga
1201 aaagctggag gaaggccgtg ggccaatggg agagctcttg ttattattaa tattgttgcc
1261 gctgttgtgt tgttgttatt aattaatatt catattattt attttatact tacataaaga
1321 ttttgtacca gtaaaaaaaa aaaaaaaaa
//