LOCUS HUMIRELA 2314 bp mRNA linear HUM 27-APR-1993
DEFINITION Homo sapiens I-Rel mRNA, complete cds.
ACCESSION M83221
VERSION M83221.1
KEYWORDS I-Rel; NF-kappa-B transcription factor inhibitor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2314)
AUTHORS Ruben,S.M., Klement,J.F., Coleman,T.A., Maher,M., Chen,C.H. and
Rosen,C.A.
TITLE I-Rel: a novel rel-related protein that inhibits NF-kappa B
transcriptional activity
JOURNAL Genes Dev. 6 (5), 745-760 (1992)
PUBMED 1577270
COMMENT Original source text: Homo sapiens (library: Jurkat T-cell in
lambda ZapII) cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2314
/db_xref="H-InvDB:HIT000196521"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat"
/cell_type="T-lymphocyte"
/tissue_lib="Jurkat T-cell in lambda ZapII"
CDS 145..1884
/function="NF-kappa-B transcpription factor p50-subunit
inhibitor"
/codon_start=1
/product="I-Rel"
/protein_id="AAA36127.1"
/translation="MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLS
LAVSRSTDELEIIDEYIKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPPA
TPPPWGCPLGRLVSPAPGPGPQPHLVITEQPKQRGMPFRYECEGRSAGSILGESSTEA
SKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSP
RHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRD
QQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDIS
VVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEP
LPFTYLPRDHDSYGVDKKAKRGMPDVLGELNSSDPHGIESKRRKKKPAILDHFLPNHG
SGPFLPPSALLPDPDFFSGTVSLPGLEPPGGPDLLDDGFAYDPTAPTLFTMLDLLPPA
PPHASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNHYREAA
FGGGLLSPGPEAT"
BASE COUNT 421 a 769 c 728 g 396 t
ORIGIN
1 ggaattcccg cccggcccgg ccccgcgccc cgcagccccg ggcgccgcgc gtcctgcccg
61 gcctgcggcc cagcccttgc gccgctcgtc cgacccgcga tcgtccacca gaccgtgcct
121 cccggccgcc cgggccccgc gtgcatgctt cggtctgggc cagcctctgg gccgtccgtc
181 cccactggcc gggccatgcc gagtcgccgc gtcgccagac cgccggctgc gccggagctg
241 ggggccttag ggtcccccga cctctcctca ctctcgctcg ccgtttccag gagcacagat
301 gaattggaga tcatcgacga gtacatcaag gagaacggct tcggcctgga cgggggacag
361 ccgggcccgg gcgaggggct gccacgcctg gtgtctcgcg gggctgcgtc cctgagcacg
421 gtcaccctgg gccctgtggc gcccccagcc acgccgccgc cttggggctg ccccctgggc
481 cgactagtgt ccccagcgcc gggcccgggc ccgcagccgc acctggtcat cacggagcag
541 cccaagcagc gcggcatgcc gttccgctac gagtgcgagg gccgctcggc cggcagcatc
601 cttggggaga gcagcaccga ggccagcaag acgctgcccg ccatcgagct ccgggattgt
661 ggagggctgc gggaggtgga ggtgactgcc tgcctggtgt ggaaggactg gcctcaccga
721 gtccaccccc acagcctcgt ggggaaagac tgcaccgacg gcatctgcag ggtgcggctc
781 cggcctcacg tcagcccccg gcacagtttt aacaacctgg gcatccagtg tgtgaggaag
841 aaggagattg aggctgccat tgagcggaag attcaactgg gcattgaccc ctacaacgct
901 gggtccctga agaaccatca ggaagtagac atgaatgtgg tgaggatctg cttccaggcc
961 tcatatcggg accagcaggg acagatgcgc cggatggatc ctgtgctttc cgagcccgtc
1021 tatgacaaga aatccacaaa cacatcagag ctgcggattt gccgaattaa caaggaaagc
1081 gggccgtgca ccggtggcga ggagctctac ttgctctgcg acaaggtgca gaaagaggac
1141 atatcagtgg tgttcagcag ggcctcctgg gaaggtcggg ctgacttctc ccaggccgac
1201 gtgcaccgcc agattgccat tgtgttcaag acgccgccct acgaggacct ggagattgtc
1261 gagcccgtga cagtcaacgt cttcctgcag cggctcaccg atggggtctg cagcgagcca
1321 ttgcctttca cgtacctgcc tcgcgaccat gacagctacg gcgtggacaa gaaggcgaaa
1381 cgggggatgc ccgacgtcct tggggagctg aacagctctg acccccatgg catcgagagc
1441 aaacggcgga agaaaaagcc ggccatcctg gaccacttcc tgcccaacca cggctcaggc
1501 ccgttcctcc cgccgtcagc cctgctgcca gaccctgact tcttctctgg caccgtgtcc
1561 ctgcccggcc tggagccccc tggcgggcct gacctcctgg acgatggctt tgcctacgac
1621 cctacggccc ccacactctt caccatgctg gacctgctgc ccccggcacc gccacacgct
1681 agcgctgttg tgtgcagcgg aggtgccggg gccgtggttg gggagacccc cggccctgaa
1741 ccactgacac tggactcgta ccaggccccg ggccccgggg atggaggcac cgccagcctt
1801 gtgggcagca acatgttccc caatcattac cgcgaggcgg cctttggggg cggcctccta
1861 tccccggggc ctgaagccac gtagccccgc gatgccagag gaggggcact gggtggggag
1921 ggaggtggag gagccgtgca atcccaacca ggatgtctag cacccccatc cccttggccc
1981 ttcctcatgc ttctgaagtg gacatattca gccttggcga gaagctccgt tgcacgggtt
2041 tccccttgag cccattttac agatgaggaa actgagtccg gagaggaaaa gggacatggc
2101 tcccgtgcac tagcttgtta cagctgcctc tgtccccaca tgtgggggca ccttctccag
2161 taggattcgg aaaagattgt acatatggga ggagggggca gattcctggc cctccctccc
2221 cagacttgac ttgaaggtgg ggggtaggtt ggttgttcag agtcttccca ataaagatga
2281 gtttttgagc ctcaaaaaaa aaaaaaggaa ttcc
//