LOCUS HUMDIPEPIV 2375 bp mRNA linear HUM 07-NOV-1994
DEFINITION H.sapiens dipeptidyl peptidase IV (DPP4) mRNA, complete cds.
ACCESSION M80536
VERSION M80536.1
KEYWORDS dipeptidyl peptidase IV.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2375)
AUTHORS Darmoul,D., Lacasa,M., Baricault,L., Marguet,D., Sapin,C.,
Trotot,P., Barbat,A. and Trugnan,G.
TITLE Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like
colon cancer cell lines HT-29 and Caco-2. Cloning of the complete
human coding sequence and changes of dipeptidyl peptidase IV mRNA
levels during cell differentiation
JOURNAL J. Biol. Chem. 267 (7), 4824-4833 (1992)
PUBMED 1347043
COMMENT Original source text: Homo sapiens intestine cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2375
/db_xref="H-InvDB:HIT000196434"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="2"
/tissue_type="intestine"
gene 1..2375
/gene="DPP4"
CDS 1..2301
/gene="DPP4"
/EC_number="3.4.14.5"
/codon_start=1
/product="dipeptidyl peptidase IV"
/protein_id="AAA52308.1"
/db_xref="GDB:G00-125-239"
/translation="MKTPWRVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYT
LTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSI
NDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPV
GHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSP
NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL
SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS
GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKK
DCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELN
PERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQ
MPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADIVFRLNWATY
LASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI
AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYESVYTERYMGLPTPEDNLDH
YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH
GIASSTAHQHIYTHMSHFIKQCFSLP"
BASE COUNT 765 a 464 c 498 g 648 t
ORIGIN chromosome 2.
1 atgaagacac cgtggagggt tctcctggga ctgctgggtg ctgctgcgct tgtcaccatc
61 atcaccgtgc ccgtggttct gctgaacaaa ggcacagatg atgctacagc tgacagtcgc
121 aaaacttaca ctctaactga ttacttaaaa aatacttata gactgaagtt atactcctta
181 agatggattt cagatcatga atatctctac aaacaagaaa ataatatctt ggtattcaat
241 gctgaatatg gaaacagctc agttttcttg gagaacagta catttgatga gtttggacat
301 tctatcaatg attattcaat atctcctgat gggcagttta ttctcttaga atacaactac
361 gtgaagcaat ggaggcattc ctacacagct tcatatgaca tttatgattt aaataaaagg
421 cagctgatta cagaagagag gattccaaac aacacacagt gggtcacatg gtcaccagtg
481 ggtcataaat tggcatatgt ttggaacaat gacatttatg ttaaaattga accaaattta
541 ccaagttaca gaatcacatg gacggggaaa gaagatataa tatataatgg aataactgac
601 tgggtttatg aagaggaagt cttcagtgcc tactctgctc tgtggtggtc tccaaacggc
661 acttttttag catatgccca atttaacgac acagaagtcc cacttattga atactccttc
721 tactctgatg agtcactgca gtacccaaag actgtacggg ttccatatcc aaaggcagga
781 gctgtgaatc caactgtaaa gttctttgtt gtaaatacag actctctcag ctcagtcacc
841 aatgcaactt ccatacaaat cactgctcct gcttctatgt tgatagggga tcactacttg
901 tgtgatgtga catgggcaac acaagaaaga atttctttgc agtggctcag gaggattcag
961 aactattcgg tcatggatat ttgtgactat gatgaatcca gtggaagatg gaactgctta
1021 gtggcacggc aacacattga aatgagtact actggctggg ttggaagatt taggccttca
1081 gaacctcatt ttacccttga tggtaatagc ttctacaaga tcatcagcaa tgaagaaggt
1141 tacagacaca tttgctattt ccaaatagat aaaaaagact gcacatttat tacaaaaggc
1201 acctgggaag tcatcgggat agaagctcta accagtgatt atctatacta cattagtaat
1261 gaatataaag gaatgccagg aggaaggaat ctttataaaa tccaacttag tgactataca
1321 aaagtgacat gcctcagttg tgagctgaat ccggaaaggt gtcagtacta ttctgtgtca
1381 ttcagtaaag aggcgaagta ttatcagctg agatgttccg gtcctggtct gcccctctat
1441 actctacaca gcagcgtgaa tgataaaggg ctgagagtcc tggaagacaa ttcagctttg
1501 gataaaatgc tgcagaatgt ccagatgccc tccaaaaaat tggacttcat tattttgaat
1561 gaaacaaaat tttggtatca gatgatcttg cctcctcatt ttgataaatc caagaaatat
1621 cctctactat tagatgtgta tgcaggccca tgtagtcaaa aagcagacat tgtcttcaga
1681 ctgaactggg ccacttacct tgcaagcaca gaaaacatta tagtagctag ctttgatggc
1741 agaggaagtg gttaccaagg agataagatc atgcatgcaa tcaacagaag actgggaaca
1801 tttgaagttg aagatcaaat tgaagcagcc agacaatttt caaaaatggg atttgtggac
1861 aacaaacgaa ttgcaatttg gggctggtca tatggagggt acgtaacctc aatggtcctg
1921 ggatcgggaa gtggcgtgtt caagtgtgga atagccgtgg cgcctgtatc ccggtgggag
1981 tactatgagt cagtgtacac agaacgttac atgggtctcc caactccaga agacaacctt
2041 gaccattaca gaaattcaac agtcatgagc agagctgaaa attttaaaca agttgagtac
2101 ctccttattc atggaacagc agatgataac gttcactttc agcagtcagc tcagatctcc
2161 aaagccctgg tcgatgttgg agtggatttc caggcaatgt ggtatactga tgaagaccat
2221 ggaatagcta gcagcacagc acaccaacat atatataccc acatgagcca cttcataaaa
2281 caatgtttct ctttacctta gcacctcaaa atactatgcc atttaaagct tattaaaact
2341 catttttgtt ttcattatct caaaaaaaaa aaaaa
//