LOCUS HUMRPKB 1849 bp mRNA linear HUM 16-OCT-2001
DEFINITION Homo sapiens rac protein kinase-beta mRNA, complete cds.
ACCESSION M77198
VERSION M77198.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1849)
AUTHORS Jones,P.F., Jakubowicz,T. and Hemmings,B.A.
TITLE Molecular cloning of a second form of rac protein kinase
JOURNAL Cell Regul. 2 (12), 1001-1009 (1991)
PUBMED 1801921
FEATURES Location/Qualifiers
source 1..1849
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="Wi38 lung fibroblasts MCF-7 epithelial cells"
/tissue_lib="MCF-7 lambda gt10; WI38 lambda gt10"
CDS 204..1766
/note="serine/threonine protein kinase"
/codon_start=1
/product="rac protein kinase-beta"
/protein_id="AAA36585.1"
/translation="MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA
PDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRA
IQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGK
GTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYA
FQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDI
KLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWW
GLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR
LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITI
TPPDRYDSLGLLELDQRTHFPQFSYSAFREEKDLLMSLFVSLILFSDFSSLKSHSFSS
NFILLSFSSLKK"
BASE COUNT 417 a 526 c 520 g 386 t
ORIGIN
1 gaattccagc ggcggcgccg ttgccgctgc cgggaaacac aaggaaaggg aaccagcgca
61 gcgtggcgat gggcgggggt agagccccgc cggagaggct gggcggctgc cggtgacaga
121 ctgtgccctg tccacggtgc ctcctgcatg tcctgctgcc ctgagctgtc ccgagctagg
181 tgacagcgta ccacgctgcc accatgaatg aggtgtctgt catcaaagaa ggctggctcc
241 acaagcgtgg tgaatacatc aagacctgga ggccacggta cttcctgctg aagagcgacg
301 gctccttcat tgggtacaag gagaggcccg aggcccctga tcagactcta ccccccttaa
361 acaacttctc cgtagcagaa tgccagctga tgaagaccga gaggccgcga cccaacacct
421 ttgtcatacg ctgcctgcag tggaccacag tcatcgagag gaccttccac gtggattctc
481 cagacgagag ggaggagtgg atgcgggcca tccagatggt cgccaacagc ctcaagcagc
541 gggccccagg cgaggacccc atggactaca agtgtggctc ccccagtgac tcctccacga
601 ctgaggagat ggaagtggcg gtcagcaagg cacgggctaa agtgaccatg aatgacttcg
661 actatctcaa actccttggc aagggaacct ttggcaaagt catcctggtg cgggagaagg
721 ccactggccg ctactacgcc atgaagatcc tgcggaagga agtcatcatt gccaaggatg
781 aagtcgctca cacagtcacc gagagccggg tcctccagaa caccaggcac ccgttcctca
841 ctgcgctgaa gtatgccttc cagacccacg accgcctgtg ctttgtgatg gagtatgcca
901 acgggggtga gctgttcttc cacctgtccc gggagcgtgt cttcacagag gagcgggccc
961 ggttttatgg tgcagagatt gtctcggctc ttgagtactt gcactcgcgg gacgtggtat
1021 accgcgacat caagctggaa aacctcatgc tggacaaaga tggccacatc aagatcactg
1081 actttggcct ctgcaaagag ggcatcagtg acggggccac catgaaaacc ttctgtggga
1141 ccccggagta cctggcgcct gaggtgctgg aggacaatga ctatggccgg gccgtggact
1201 ggtgggggct gggtgtggtc atgtacgaga tgatgtgcgg ccgcctgccc ttctacaacc
1261 aggaccacga gcgcctcttc gagctcatcc tcatggaaga gatccgcttc ccgcgcacgc
1321 tcagccccga ggccaagtcc ctgcttgctg ggctgcttaa gaaggacccc aagcagaggc
1381 ttggtggggg gcccagcgat gccaaggagg tcatggagca caggttcttc ctcagcatca
1441 actggcagga cgtggtccag aagaagctcc tgccaccctt caaacctcag gtcacgtccg
1501 aggtcgacac aaggtacttc gatgatgaat ttaccgccca gtccatcaca atcacacccc
1561 ctgaccgcta tgacagcctg ggcttactgg agctggacca gcggacccac ttcccccagt
1621 tctcctactc ggctttccga gaagagaaag acctgctgat gtctttgttt gtgtctttga
1681 ttctcttcag tgatttttca tctttaaaga gccattcttt ttcttctaat ttcattttgc
1741 taagtttctc ttctttgaag aaataaaatc catgatggaa gagatggtgg catctgtata
1801 tttaattgtc ttctatacag cctagaccag aattataaac tagaattcc
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