LOCUS HUMCABCNLS 1546 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human neuronal DHP-sensitive, voltage-dependent, calcium channel
beta-2 subunit mRNA, complete cds.
ACCESSION M76560
VERSION M76560.1
KEYWORDS neuronal DHP-sensitive calcium channel; transmembrane protein;
voltage-dependent calcium channel beta-2 subunit; voltage-gated
calcium channel.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1546)
AUTHORS Williams,M.E., Feldman,D.H., McCue,A.F., Brenner,R., Velicelebi,G.,
Ellis,S.B. and Harpold,M.M.
TITLE Structure and functional expression of alpha 1, alpha 2, and beta
subunits of a novel human neuronal calcium channel subtype
JOURNAL Neuron 8 (1), 71-84 (1992)
PUBMED 1309651
COMMENT Original source text: Homo sapiens (tissue library: lambda gt11)
central nervous system cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1546
/db_xref="H-InvDB:HIT000196372"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/tissue_type="central nervous system"
/tissue_lib="lambda gt11"
gene 1..1546
/gene="CCHL1A2"
CDS 1..1437
/gene="CCHL1A2"
/codon_start=1
/product="voltage-dependent calcium channel beta-2
subunit"
/protein_id="AAA51894.1"
/db_xref="GDB:G00-128-872"
/translation="MVQKTSMSRGPYPPSQEIPMGVFDPSPQGKYSKRKGRFKRSDGS
TSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVA
FAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIP
SPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTE
HVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLA
KRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSK
TSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDEN
QLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTS
LRRNLGFWGGLESSQRGSVVPQEQEHAM"
BASE COUNT 371 a 466 c 422 g 287 t
ORIGIN
1 atggtccaga agaccagcat gtcccggggc ccttacccac cctcccagga gatccccatg
61 ggagtcttcg accccagccc gcagggcaaa tacagcaaga ggaaagggcg attcaaacgg
121 tcagatggga gcacgtcctc ggataccaca tccaacagct ttgtccgcca gggctcagcg
181 gagtcctaca ccagccgtcc atcagactct gatgtatctc tggaggagga ccgggaagcc
241 ttaaggaagg aagcagagcg ccaggcatta gcgcagctcg agaaggccaa gaccaagcca
301 gtggcatttg ctgtgcggac aaatgttggc tacaatccgt ctccagggga tgaggtgcct
361 gtgcagggag tggccatcac cttcgagccc aaagacttcc tgcacatcaa ggagaaatac
421 aataatgact ggtggatcgg gcggctggtg aaggagggct gtgaggttgg cttcattccc
481 agccccgtca aactggacag ccttcgcctg ctgcaggaac agaagctgcg ccagaaccgc
541 ctcggctcca gcaaatcagg cgataactcc agttccagtc tgggagatgt ggtgactggc
601 acccgccgcc ccacaccccc tgccagtgcc aaacagaagc agaagtcgac agagcatgtg
661 cccccctatg acgtggtgcc ttccatgagg cccatcatcc tggtgggacc gtcgctcaag
721 ggctacgagg ttacagacat gatgcagaaa gctttatttg acttcttgaa gcatcggttt
781 gatggcagga tctccatcac tcgtgtgacg gcagatattt ccctggctaa gcgctcagtt
841 ctcaacaacc ccagcaaaca catcatcatt gagcgctcca acacacgctc cagcctggct
901 gaggtgcaga gtgaaatcga gcgaatcttc gagctggccc ggacccttca gttggtcgct
961 ctggatgctg acaccatcaa tcacccagcc cagctgtcca agacctcgct ggcccccatc
1021 attgtttaca tcaagatcac ctctcccaag gtacttcaaa ggctcatcaa gtcccgagga
1081 aagtctcagt ccaaacacct caatgtccaa atagcggcct cggaaaagct ggcacagtgc
1141 ccccctgaaa tgtttgacat catcctggat gagaaccaat tggaggatgc ctgcgagcat
1201 ctggcggagt acttggaagc ctattggaag gccacacacc cgcccagcag cacgccaccc
1261 aatccgctgc tgaaccgcac catggctacc gcagccctgg ctgccagccc tgcccctgtc
1321 tccaacctcc aggtacaggt gctcacctcg ctcaggagaa acctcggctt ctggggcggg
1381 ctggagtcct cacagcgggg cagtgtggtg ccccaggagc aggaacatgc catgtagtgg
1441 gcgccctgcc cgtcttccct cctgctctgg ggtcggaact ggagtgcagg gaacatggag
1501 gaggaaggga agagctttat tttgtaaaaa aataagatga gcggca
//