LOCUS HUMA1AADR 2002 bp mRNA linear HUM 27-APR-1993
DEFINITION Human alpha-A1-adrenergic receptor mRNA, complete cds.
ACCESSION M76446
VERSION M76446.1
KEYWORDS G-protein linked receptor; alpha-1A-adrenergic receptor;
transmembrane protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2002)
AUTHORS Bruno,J.F., Whittaker,J., Song,J.F. and Berelowitz,M.
TITLE Molecular cloning and sequencing of a cDNA encoding a human alpha
1A adrenergic receptor
JOURNAL Biochem. Biophys. Res. Commun. 179 (3), 1485-1490 (1991)
PUBMED 1656955
COMMENT Original source text: Homo sapiens female 2 years old brain cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..2002
/db_xref="H-InvDB:HIT000196365"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="female"
/tissue_type="brain"
/dev_stage="2 years old"
CDS 56..1561
/codon_start=1
/product="alpha-1A-adrenergic receptor"
/protein_id="AAA35496.1"
/translation="MAAALRSVMMAGYLSEWRTPTYRSTEMVQRLRMEAVQHSTSTAA
VGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLL
LSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSL
KYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSV
CSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGA
HGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQ
LKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVY
GHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRSHPA
PSASGGCWGRSGDPRPSCAPKSPACRTRSPPGARSAQRQRAPSAQRWRLCP"
BASE COUNT 307 a 697 c 643 g 355 t
ORIGIN
1 cccgtgcagg ggccctacgg acaccaccag ggctacgacc cagagcaggg ccaggatggc
61 ggccgccttg cgctcggtca tgatggctgg gtacttgagt gagtggcgca cgcccacgta
121 ccggtccacg gagatggtgc agaggctgag gatggaggcc gtgcagcaca gcacgtccac
181 ggcggccgtc gggggactgg tggtgagcgc gcagggcgtg ggcgtgggcg tcttcctggc
241 agccttcatc cttatggccg tggcaggtaa cctgcttgtc atcctctcag tggcctgcaa
301 ccgccacctg cagaccgtca ccaactattt catcgtgaac ctggccgtgg ccgacctgct
361 gctgagcgcc accgtactgc ccttctcggc caccatggag gttctgggct tctgggcctt
421 tggccgcgcc ttctgcgacg tatgggccgc cgtggacgtg ctgtgctgca cggcctccat
481 cctcagcctc tgcaccatct ccgtggaccg gtacgtgggc gtgcgccact cactcaagta
541 cccagccatc atgaccgagc gcaaggcggc cgccatcctg gccctgctct gggtcgtagc
601 cctggtggtg tccgtagggc ccctgctggg ctggaaggag cccgtgcccc ctgacgagcg
661 cttctgcggt atcaccgagg aggcgggcta cgctgtcttc tcctccgtgt gctccttcta
721 cctgcccatg gcggtcatcg tggtcatgta ctgccgcgtg tacgtggtcg cgcgcagcac
781 cacgcgcagc ctcgaggcag gcgtcaagcg cgagcgaggc aaggcctccg aggtggtgct
841 gcgcatccac tgtcgcggcg cggccacggg cgccgacggg gcgcacggca tgcgcagcgc
901 caagggccac accttccgca gctcgctctc cgtgcgcctg ctcaagttct cccgtgagaa
961 gaaagcggcc aagactctgg ccatcgtcgt gggtgtcttc gtgctctgct ggttcccttt
1021 cttctttgtc ctgccgctcg gctccttgtt cccgcagctg aagccatcgg agggcgtctt
1081 caaggtcatc ttctggctcg gctacttcaa cagctgcgtg aacccgctca tctacccctg
1141 ttccagccgc gagttcaagc gcgccttcct ccgtctcctg cgctgccagt gccgtcgtcg
1201 ccggcgccgc cgccctctct ggcgtgtcta cggccaccac tggcgggcct ccaccagcgg
1261 cctgcgccag gactgcgccc cgagttcggg cgacgcgccc cccggagcgc cgctggccct
1321 caccgcgctc cccgaccccg accccgaacc cccaggcacg cccgagatgc aggctccggt
1381 cgccagccgt cgaagccacc cagcgccttc cgcgagtgga ggctgctggg gccgttccgg
1441 agacccacga cccagctgcg cgccaaagtc tccagcctgt cgcacaagat cgccgccggg
1501 ggcgcgcagc gcgcagaggc agcgtgcgcc cagcgctcag aggtggaggc tgtgtcccta
1561 ggcgtcccac acgaggtggc cgagggcgcc acctgccagg cctacgaatt ggccgactac
1621 agcaacctac gggagaccga tatttaagga ccccagagct aggccgcgga gtgtgctggg
1681 cttgggggta agggggacca gagaggcggg ctggtgttct aagagccccc gtgcaaatcg
1741 gagacccgga aactgatcag ggcagctgct ctgtgacatc cctgaggaac tgggcagagc
1801 ttgaggctgg agcccttgaa aggtgaaaag tagtggggcc ccctgctgga ctcaggtgcc
1861 cagaactctt ttcttagaag ggagaggctg cgggctccgt ggggcctttt gctcccaatc
1921 cctatttgag aaacactgcc ccatcctcca tgccctgaac cctgagtaga cagccccaag
1981 catggccagg aaggcctgcc cc
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