LOCUS HUMGRANUL 2095 bp mRNA linear HUM 31-DEC-1994
DEFINITION H.sapiens granulin mRNA, complete cds.
ACCESSION M75161
VERSION M75161.1
KEYWORDS granulin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2095)
AUTHORS Bhandari,V., Palfree,R.G. and Bateman,A.
TITLE Isolation and sequence of the granulin precursor cDNA from human
bone marrow reveals tandem cysteine-rich granulin domains
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1715-1719 (1992)
PUBMED 1542665
COMMENT Original source text: Homo sapiens (tissue library: Clontech
HL1058b) adult bone marrow mRNA.
FEATURES Location/Qualifiers
source 1..2095
/db_xref="H-InvDB:HIT000196354"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="bone marrow"
/dev_stage="adult"
/tissue_lib="Clontech HL1058b"
gene 1..2095
/gene="granulin"
CDS 13..1794
/gene="granulin"
/codon_start=1
/product="granulin"
/protein_id="AAA58617.1"
/translation="MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRP
LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRG
FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCED
RVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDG
STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPA
HTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGT
CEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIP
EAVCCSDHQHCCPQRYTCVAEGQCQRGSEIVAGLEKMPARRGSLSHPRDIGCDQHTSC
PVGGTCCPSQGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFL
ARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYAQGVCCADRRHCCPAGFRCA
RRGTKCLRREAPRWDAPLRDPALRQLL"
sig_peptide 13..63
/gene="granulin"
/note="presumed signal peptide"
mat_peptide 64..1791
/gene="granulin"
/product="granulin"
/note="presumed mature peptide"
regulatory 2075..2080
/regulatory_class="polyA_signal_sequence"
/gene="granulin"
BASE COUNT 364 a 682 c 624 g 425 t
ORIGIN
1 cgcaggcaga ccatgtggac cctggtgagc tgggtggcct taacagcagg gctggtggct
61 ggaacgcggt gcccagatgg tcagttctgc cctgtggcct gctgcctgga ccccggagga
121 gccagctaca gctgctgccg tccccttctg gacaaatggc ccacaacact gagcaggcat
181 ctgggtggcc cctgccaggt tgatgcccac tgctctgccg gccactcctg catctttacc
241 gtctcaggga cttccagttg ctgccccttc ccagaggccg tggcatgcgg ggatggccat
301 cactgctgcc cacggggctt ccactgcagt gcagacgggc gatcctgctt ccaaagatca
361 ggtaacaact ccgtgggtgc catccagtgc cctgatagtc agttcgaatg cccggacttc
421 tccacgtgct gtgttatggt cgatggctcc tgggggtgct gccccatgcc ccaggcttcc
481 tgctgtgaag acagggtgca ctgctgtccg cacggtgcct tctgcgacct ggttcacacc
541 cgctgcatca cacccacggg cacccacccc ctggcaaaga agctccctgc ccagaggact
601 aacagggcag tggccttgtc cagctcggtc atgtgtccgg acgcacggtc ccggtgccct
661 gatggttcta cctgctgtga gctgcccagt gggaagtatg gctgctgccc aatgcccaac
721 gccacctgct gctccgatca cctgcactgc tgcccccaag acactgtgtg tgacctgatc
781 cagagtaagt gcctctccaa ggagaacgct accacggacc tcctcactaa gctgcctgcg
841 cacacagtgg gcgatgtgaa atgtgacatg gaggtgagct gcccagatgg ctatacctgc
901 tgccgtctac agtcgggggc ctggggctgc tgccctttta cccaggctgt gtgctgtgag
961 gaccacatac actgctgtcc cgcggggttt acgtgtgaca cgcagaaggg tacctgtgaa
1021 caggggcccc accaggtgcc ctggatggag aaggccccag ctcacctcag cctgccagac
1081 ccacaagcct tgaagagaga tgtcccctgt gataatgtca gcagctgtcc ctcctccgat
1141 acctgctgcc aactcacgtc tggggagtgg ggctgctgtc caatcccaga ggctgtctgc
1201 tgctcggacc accagcactg ctgcccccag cgatacacgt gtgtagctga ggggcagtgt
1261 cagcgaggaa gcgagatcgt ggctggactg gagaagatgc ctgcccgccg cggttcctta
1321 tcccacccca gagacatcgg ctgtgaccag cacaccagct gcccggtggg cggaacctgc
1381 tgcccgagcc agggtgggag ctgggcctgc tgccagttgc cccatgctgt gtgctgcgag
1441 gatcgccagc actgctgccc ggctggctac acctgcaacg tgaaggctcg atcctgcgag
1501 aaggaagtgg tctctgccca gcctgccacc ttcctggccc gtagccctca cgtgggtgtg
1561 aaggacgtgg agtgtgggga aggacacttc tgccatgata accagacctg ctgccgagac
1621 aaccgacagg gctgggcctg ctgtccctac gcccagggcg tctgttgtgc tgatcggcgc
1681 cactgctgtc ctgctggctt ccgctgcgca cgcaggggta ccaagtgttt gcgcagggag
1741 gccccgcgct gggacgcccc tttgagggac ccagccttga gacagctgct gtgagggaca
1801 gtactgaaga ctctgcagcc ctcgggaccc cactcggagg gtgccctctg ctcaggcctc
1861 cctagcacct ccccctaacc aaattctccc tggaccccat tctgagctcc ccatcaccat
1921 gggaggtggg gcctcaatct aaggcccttc cctgtcagaa gggggttgag gcaaaagccc
1981 attacaagct gccatcccct ccccgtttca gtggaccctg tggccaggtg cttttcccta
2041 tccacagggg tgtttgtgtg ttgggtgtgc tttcaataaa gtttgtcact ttctt
//