LOCUS HUMIL3B 1460 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human interleukin 3 receptor (hIL-3Ra) mRNA, complete cds.
ACCESSION M74782
VERSION M74782.1
KEYWORDS cytokine receptor; interleukin 3 receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1460)
AUTHORS Kitamura,T., Sato,N., Arai,K. and Miyajima,A.
TITLE Expression cloning of the human IL-3 receptor cDNA reveals a shared
beta subunit for the human IL-3 and GM-CSF receptors
JOURNAL Cell 66 (6), 1165-1174 (1991)
PUBMED 1833064
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1460
/db_xref="H-InvDB:HIT000196340_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="homopoietic TF-1"
gene 1..1460
/gene="hIL-3Ra"
CDS 147..1283
/gene="hIL-3Ra"
/codon_start=1
/product="interleukin 3 receptor"
/protein_id="AAA59148.1"
/translation="MVLLWLTLLLIALPCLLQTKEDPNPPITNLRMKAKAQQLTWDLN
RNVTDIECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVANPPFSTWILFPENSGK
PWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQG
TRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPNMTAKCN
KTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARE
RVYEFLSAWSTPQRFECDQEEGANTRAWRTSLLIALGTLLALVCVFVICRRYLVMQRL
FPRIPHMKDPIGDSFQNDKLVVWEAGKAGLEECLVTEVQVVQKT"
sig_peptide 147..200
/gene="hIL-3Ra"
mat_peptide 201..1280
/gene="hIL-3Ra"
/product="interleukin 3 receptor"
BASE COUNT 358 a 396 c 391 g 315 t
ORIGIN
1 gcacacggga agatatcaga aacatcctag gatcaggaca ccccagatct tctcaactgg
61 aaccacgaag gctgtttctt ccacacagca ctttgatctc catttaagca ggcacctctg
121 tcctgcgttc cggagctgcg ttcccgatgg tcctcctttg gctcacgctg ctcctgatcg
181 ccctgccctg tctcctgcaa acgaaggaag atccaaaccc accaatcacg aacctaagga
241 tgaaagcaaa ggctcagcag ttgacctggg accttaacag aaatgtgacc gatatcgagt
301 gtgttaaaga tgccgactat tctatgccgg cagtgaacaa tagctattgc cagtttggag
361 caatttcctt atgtgaagtg accaactaca ccgtccgagt ggccaaccca ccattctcca
421 cgtggatcct cttccctgag aacagtggga agccttgggc aggtgcggag aatctgacct
481 gctggattca tgacgtggat ttcttgagct gcagctgggc ggtaggcccg ggggcccccg
541 cggacgtcca gtacgacctg tacttgaacg ttgccaacag gcgtcaacag tacgagtgtc
601 ttcactacaa aacggatgct cagggaacac gtatcgggtg tcgtttcgat gacatctctc
661 gactctccag cggttctcaa agttcccaca tcctggtgcg gggcaggagc gcagccttcg
721 gtatcccctg cacagataag tttgtcgtct tttcacagat tgagatatta actccaccca
781 acatgactgc aaagtgtaat aagacacatt cctttatgca ctggaaaatg agaagtcatt
841 tcaatcgcaa atttcgctat gagcttcaga tacaaaagag aatgcagcct gtaatcacag
901 aacaggtcag agacagaacc tccttccagc tactcaatcc tggaacgtac acagtacaaa
961 taagagcccg ggaaagagtg tatgaattct tgagcgcctg gagcaccccc cagcgcttcg
1021 agtgcgacca ggaggagggc gcaaacacac gtgcctggcg gacgtcgctg ctgatcgcgc
1081 tggggacgct gctggccctg gtctgtgtct tcgtgatctg cagaaggtat ctggtgatgc
1141 agagactctt tccccgcatc cctcacatga aagaccccat cggtgacagc ttccaaaacg
1201 acaagctggt ggtctgggag gcgggcaaag ccggcctgga ggagtgtctg gtgactgaag
1261 tacaggtcgt gcagaaaact tgagactggg gttcagggct tgtgggggtc tgcctcaatc
1321 tccctggccg ggccaggcgc ctgcacagac tggctgctgg acctgcgcac gcagcccagg
1381 aatggacatt cctaacgggt ggtgggcatg ggagatgcct gtgtaatttc gtccgaagct
1441 gccaggaaga agaacagaac
//