LOCUS HUMSIL 5198 bp mRNA linear HUM 13-JAN-1995
DEFINITION Human SIL mRNA, complete cds.
ACCESSION M74558
VERSION M74558.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5198)
AUTHORS Aplan,P.D., Lombardi,D.P. and Kirsch,I.R.
TITLE Structural characterization of SIL, a gene frequently disrupted in
T-cell acute lymphoblastic leukemia
JOURNAL Mol. Cell. Biol. 11 (11), 5462-5469 (1991)
PUBMED 1922059
COMMENT Original source text: Homo sapiens Bone marrow cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..5198
/db_xref="H-InvDB:HIT000196331"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="Bone marrow"
/germline
gene 1..5198
/gene="SIL"
CDS 381..4244
/gene="SIL"
/codon_start=1
/protein_id="AAA60550.1"
/translation="MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIY
LHLSYYRNPKLVVTEKTIRLAYRHANENKKNSSCFLLGSLTADEDEEGVTLTVDRFDP
GREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSK
DSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNL
SSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVW
ACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSK
ETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHD
HDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNN
ENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQP
PAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLA
PQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGAN
TVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEP
SPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQI
QRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASL
FWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEES
NIAVEEEFNQPLSVSNSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSET
SEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTR
TQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLAC
ISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQN
NCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNAD
SKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQ
TKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETL
KQMNSMNSVGTFLDVKRLRQLPKLF"
BASE COUNT 1565 a 1141 c 1059 g 1433 t
ORIGIN
1 ctcacttaaa cacgtagttc ccgcgacccc aacgtcccag aggcggggcc ggagtcggcg
61 gtggcgctcc ttggagccgg ctcccgctcc taccctgcaa acagacctca gctccgcgga
121 agttgcgaga cggggtttca ccatgttggt cgggctggtc tggaaatcct gacttcaggt
181 gatccacccg cctcggcctc ccaaaatgct gggattacaa gcgtgagcca ccgcccctga
241 catgagccat tgacttttaa agcaggagaa taatttggat cagatttata tggaaacact
301 cttctagcag cattatgggg acttttccat aagtctggat actgaggatt tggaattaaa
361 gaaatcattc accagacatc atggagccta tatatccttt tgcacggccc cagatgaata
421 ccaggtttcc ttcaagcagg atggtacctt tccactttcc tccatcaaaa tgtgcacttt
481 ggaacccaac gccaactgga gatttcatct acttacatct cagttactac agaaatccaa
541 agcttgtggt gactgagaag accatccgac ttgcttatcg tcatgctaac gagaataaaa
601 aaaattcgtc atgcttttta cttggttctc tgacagcaga cgaagatgaa gaaggtgtaa
661 cattgacagt agatcgcttt gatcctggtc gagaagtacc tgaatgccta gaaataaccc
721 ctactgcttc tcttcctggg gactttttga ttccatgcaa agttcatact caagaacttt
781 gttcaagaga aatgatagtt cacagtgtag atgacttcag ttcagcttta aaggctctac
841 agtgccatat atgtagcaaa gattccttgg actgtggtaa gctgctttcc ctaagagttc
901 atatcacttc cagggagagt ttggacagtg tggaatttga cttgcattgg gcagcagtaa
961 ctctagcaaa taactttaaa tgcacacctg tgaagcccat ccccattatt ccaacagctc
1021 tggcaagaaa cttgagcagt aatctgaata tttctcaagt tcaagggact tataaatatg
1081 gatatcttac catggatgaa acacgcaaat tgttactttt gttggaatct gatcccaagg
1141 tttattctct accattggtg ggaatttggc tgtctggaat tacacatatc tatagtcctc
1201 aggtatgggc ttgctgtttg cgatacatat tcaattcttc tgttcaagaa agggtttttt
1261 cagaatctgg aaatttcatc atagttctct attctatgac acataaggaa cctgagtttt
1321 atgaatgctt cccttgtgat ggcaagatac ctgactttcg gtttcagttg ctaaccagta
1381 aggaaacatt acatcttttc aaaaatgttg aacctcctga caaaaatcca atccgttgtg
1441 aactgagcgc tgaaagccaa aatgcagaaa cagagttttt cagtaaggct tccaagaatt
1501 tttcaattaa gaggtcttcc caaaagttat cttctgggaa gatgccaata catgatcacg
1561 actctggtgt tgaagatgaa gatttttctc caagaccaat tcctagtcct catccagtga
1621 gtcagaagat ttctaagatc caaccatcag ttcctgaact ttcacttgtg ttggatggca
1681 atttcataga atcaaaccct ctgcctactc cattggaaat ggtgaataat gaaaatcctc
1741 ctttgattaa ccacttggaa cacttgaagc cattgcaacc ccagctttat gatgagaaac
1801 acagtccaga agttgaagct ggagagcctt ccttgagagg aataccaaat cagttaaacc
1861 aggataaacc agctcttttg agacactgca aagtaagaca gccacctgcc tataagaaag
1921 ggaaccccca taccaggaac agtattaaac catcttctca taatgggcca tctcatgata
1981 tatttgaaaa gctccaaaca gtttctgctg gaaatgtaca aaacgaagag tatcctataa
2041 gaccctccac acttaattct aggcagtctt ctcttgcccc gcagtcccaa ccacacgatt
2101 ttgttttttc accccataat tcaggaagac caatggaact tcagatacct actcccccac
2161 tgccatctta ctgttccaca aacgtttgca ggtgttgtca gcatcatagt catattcaat
2221 atagtccgct aaattcttgg caaggagcaa acacagttgg atccattcaa gatgtccagt
2281 ctgaagccct tcaaaagcat tcattatttc acccaagtgg atgtccagcc ctgtactgta
2341 atgcattctg ttcttcaagt agtcctatag ccttgagacc tcagggagat atgggcagtt
2401 gttctcccca cagcaatatt gaaccatcgc ctgtggcaag accgccttca catatggact
2461 tatgtaaccc acagccttgc acagtgtgca tgcacacacc caagactgag tcagataatg
2521 gaatgatggg actatctcca gatgcatatc ggttcctcac agaacaagac agacagctaa
2581 gactacttca ggcacagatt cagcgtttgt tggaagcaca gtctctgatg ccctgttccc
2641 ctaagacaac tgctgttgaa gacacagtgc aagctggaag acaaatggag ttggtttctg
2701 tggaagcaca gtcttcccct ggcttgcaca tgagaaaagg tgtaagcatt gctgtgagca
2761 caggtgctag cttgttttgg aatgcagcag gtgaggatca agagcctgac tctcaaatga
2821 agcaagatga taccaaaatt tccagtgagg acatgaattt ttctgtcgat attaataatg
2881 aagtcacaag tcttccaggt agtgcatctt cattaaaagc agttgatatt cccagttttg
2941 aagagagcaa cattgctgtg gaagaagaat ttaaccagcc actttctgta tccaactctt
3001 ctctagttgt gagaaaagaa cctgatgtac ctgtgttctt tccaagtggc cagctggcag
3061 aaagtgtaag catgtgttta cagactggac caacaggggg tgccagtaac aattctgaaa
3121 catcagagga accaaaaatt gagcatgtaa tgcaaccctt gcttcatcaa ccatcagata
3181 accagaaaat ttaccaggat ttattgggtc aagtaaacca cctattaaat agttcctcca
3241 aggaaactga gcagccgtct accaaagcag taattatcag tcatgaatgc accagaaccc
3301 aaaacgttta ccatacaaag aaaaaaacac atcattcaag actggtggac aaagattgtg
3361 tccttaatgc aactcttaag caactaagaa gccttggagt aaaaattgat tctcccacta
3421 aagtgaagaa aaatgcacat aacgtggatc acgccagtgt gttggcatgc atcagcccag
3481 aagcagtgat ctctggatta aactgcatgt catttgctaa tgttggcatg agcggcttaa
3541 gccccaatgg tgtggatttg agcatggagg caaatgctat agctctgaaa tatttaaatg
3601 aaaatcagct gtcacaactg tctgtcactc gatcgaacca aaataattgt gacccattca
3661 gccttctcca tattaataca gacagaagca cagtggggct tagtttaatt tcaccaaaca
3721 acatgtcatt tgcaaccaaa aaatatatga agagatatgg actcctacaa agcagtgaca
3781 atagtgaaga tgaagaggaa cctcccgaca atgcagatag caagagtgaa tatttattga
3841 atcagaacct taggtccata cccgaacagc ttggtggtca gaaagagcct tctaagaatg
3901 accatgaaat aattaattgt tctaactgtg aatctgtggg gaccaacgca gatacgccag
3961 tattgagaaa tattacaaat gaagttttgc agacaaaagc aaaacagcag ttgactgaaa
4021 agccagcttt cttagtaaag aaccttaaac caagtcctgc agtgaacctt cgaaccggga
4081 aagcagagtt cactcaacat cctgagaaag aaaatgaagg ggacattaca atttttcctg
4141 aaagtttgca accttctgaa acgctaaagc agatgaatag catgaattca gtaggcacct
4201 tcttagatgt aaaacgtctc agacagttac caaaattatt ttaacctttt aactccctgc
4261 ccttttaata cagggacagg gtgtctcctg aagatactta gggaaaacag gagcctacca
4321 caaggctcct gatcattctg gagtcactgt ttcttggtag cagccaattg ggaagagtga
4381 cttctgtgag atggctggct ggtgatagga ctaagttctc attgttcaaa tagagctgtt
4441 caacatcact gaaaccttta agaaaagccc tgagatcagt tattcctaca agtttaagta
4501 gtagacagat actatccagc tctaagtctc aactgctctt ttatactgta cttttttttt
4561 tgagacggag ttttgctctt gtagcccagg ctggagtgca atggcaggat ctcagatcac
4621 tgcaacctct gcctcctggg ttcaagcgat tttcctgctt catcttccca ggtagctggg
4681 attacaggca tgtgccacaa cgcctggcta attttgtatt tttagtagag actggtttct
4741 ccatgttggt caggctggtc tcaaactccc gacctcaggt gatccgcccg cctcggcctc
4801 ctaaagtgct gggattacag gcgtgagcca ctgcccagct atactgtata tttaagaagg
4861 tccagcatgt tgcatctctg cattatccta tatcataaaa gaagcataag ttatcatggt
4921 gttgggtaaa ttagcgaaat caaccgcttc ctaagtttaa gggaaaagtt atttttaaaa
4981 acaacttaat aaaaacttac actcttatac aagagtgtat ttccccttaa ttaggatgca
5041 tgttgattaa actcgagata cagctttttg cagtatggtg ggttggtttt ggtgtaacat
5101 cttcaacatg tcacactggc tatcaaagaa taagaaaatt attgagtatg agtgtgtttt
5161 ataaactttc tgagtttttc agatgtctta atattttt
//