LOCUS HUMMHPSF2A 2553 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human PSF-2 mRNA, complete cds.
ACCESSION M74447
VERSION M74447.1
KEYWORDS class II region; major histocompatibility complex.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2553)
AUTHORS Bahram,S., Arnold,D., Bresnahan,M., Strominger,J.L. and Spies,T.
TITLE Two putative subunits of a peptide pump encoded in the human major
histocompatibility complex class II region
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (22), 10094-10098 (1991)
PUBMED 1946428
COMMENT Original source text: Homo sapiens (tissue library: HPB-ALL cDNA)
cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2553
/db_xref="H-InvDB:HIT000196320_06"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="chromosome 6, short"
/tissue_lib="HPB-ALL cDNA"
gene 1..2553
/gene="PSF-2"
mRNA 1..2553
/gene="PSF-2"
CDS 97..2208
/gene="PSF-2"
/note="putative peptide pump; putative"
/codon_start=1
/protein_id="AAA59841.1"
/translation="MRLPDLRPWTSLLLVDAALLWLLQGPLGTLLPQGLPGLWLEGTL
RLGGLWGLLKLRGLLGFVGTLLLPLCLATPLTVSLRALVAGASRAPPARVASAPWSWL
LVGYGAAGLSWSLWAVLSPPGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLV
LAVLGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTM
SRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLV
KVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVRE
AVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLIRRVLHLGVQMLML
SCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQ
PNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSG
KSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAY
GLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRD
PRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQAVQRAHQILVLQEGKLQK
LAQLQEGQDLYSRLVQQRLMD"
BASE COUNT 489 a 675 c 806 g 583 t
ORIGIN chromosome 6, short arm, 15kb upstream of DOB gene.
1 ggaccagagc cggtagcgag gttgggagag acggagcgga cctcagcgct gaagcagaag
61 tccccggagc tgcggtctcc ccgccgcggc tgagccatgc ggctccctga cctgagaccc
121 tggacctccc tgctgctggt ggacgcggct ttactgtggc tgcttcaggg ccctctgggg
181 actttgcttc ctcaagggct gccaggacta tggctggagg ggaccctgcg gctgggaggg
241 ctgtgggggc tgctaaagct aagagggctg ctgggatttg tggggacact gctgctcccg
301 ctctgtctgg ccacccccct gactgtctcc ctgagagccc tggtcgcggg ggcctcacgt
361 gctcccccag ccagagtcgc ttcagcccct tggagctggc tgctggtggg gtacggggct
421 gcggggctca gctggtcact gtgggctgtt ctgagccctc ctggagccca ggagaaggag
481 caggaccagg tgaacaacaa agtcttgatg tggaggctgc tgaagctctc caggccggac
541 ctgcctctcc tcgttgccgc cttcttcttc cttgtccttg ctgttttggg tgagacatta
601 atccctcact attctggtcg tgtgattgac atcctgggag gtgattttga cccccatgcc
661 tttgccagtg ccatcttctt catgtgcctc ttctcctttg gcagctcact gtctgcaggc
721 tgccgaggag gctgcttcac ctacaccatg tctcgaatca acttgcggat ccgggagcag
781 cttttctcct ccctgctgcg ccaggacctc ggtttcttcc aggagactaa gacaggggag
841 ctgaactcac ggctgagctc ggataccacc ctgatgagta actggcttcc tttaaatgcc
901 aatgtgctct tgcgaagcct ggtgaaagtg gtggggctgt atggcttcat gctcagcata
961 tcgcctcgac tcaccctcct ttctctgctg cacatgccct tcacaatagc agcggagaag
1021 gtgtacaaca cccgccatca ggaagtgctt cgggagatcc aggatgcagt ggccagggcg
1081 gggcaggtgg tgcgggaagc cgttggaggg ctgcagaccg ttcgcagttt tggggccgag
1141 gagcatgaag tctgtcgcta taaagaggcc cttgaacaat gtcggcagct gtattggcgg
1201 agagacctgg aacgcgcctt gtacctgctc ataaggaggg tgctgcactt gggggtgcag
1261 atgctgatgc tgagctgtgg gctgcagcag atgcaggatg gggagctcac ccagggcagc
1321 ctgctttcct ttatgatcta ccaggagagc gtggggagct atgtgcagac cctggtatac
1381 atatatgggg atatgctcag caacgtggga gctgcagaga aggttttctc ctacatggac
1441 cgacagccaa atctgccttc acctggcacg cttgccccca ccactctgca gggggttgtg
1501 aaattccaag acgtctcctt tgcatatccc aatcgccctg acaggcctgt gctcaagggg
1561 ctgacgttta ccctacgtcc tggtgaggtg acggcgctgg tgggacccaa tgggtctggg
1621 aagagcacag tggctgccct gctgcagaat ctgtaccagc ccacaggggg acaggtgctg
1681 ctggatgaaa agcccatctc acagtatgaa cactgctacc tgcacagcca ggtggtttca
1741 gttgggcagg agcctgtgct gttctccggt tctgtgagga acaacattgc ttatgggctg
1801 cagagctgcg aagatgataa ggtgatggcg gctgcccagg ctgcccacgc agatgacttc
1861 atccaggaaa tggagcatgg aatatacaca gatgtagggg agaagggaag ccagctggct
1921 gcgggacaga aacaacgtct ggccattgcc cgggcccttg tacgagaccc gcgggtcctc
1981 atcctggatg aggctactag tgccctagat gtgcagtgcg agcaggccct gcaggactgg
2041 aattcccgtg gggatcgcac agtgctggtg attgctcaca ggctgcaggc agttcagcgc
2101 gcccaccaga tcctggtgct ccaggagggc aagctgcaga agcttgccca gctccaggag
2161 ggacaggacc tctattcccg cctggttcag cagcggctga tggactgagg ccccagggat
2221 actgggccct cttctcaggg gcgtctccag gacccagagc tgttcctgct ttgagtttcc
2281 ctagagctgt gcggccagat agctgttcct gagttgcaag cacgatggag atttggacac
2341 tgtgtgcttt tggtggggtg gagaggtggg gtggggtggg gtgtggtggg gtgggaggct
2401 gtctgtgtcc aggaaactta attccctggt gactagagct ttgcctggtg atgaggagta
2461 ttttgtggca taatacatat attttaaaat attttccttc ttacgtgaac tgtatacatt
2521 catatagaaa atttagacaa tataaaaaag tac
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