LOCUS HUMACADL 2217 bp mRNA linear HUM 30-OCT-1994
DEFINITION Human long chain acyl-CoA dehydrogenase (ACADL) mRNA, complete cds.
ACCESSION M74096
VERSION M74096.1
KEYWORDS fatty acid oxidation; long chain acyl-CoA dehydrogenase;
mitochondrial matrix enzyme.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2217)
AUTHORS Indo,Y., Yang-Feng,T., Glassberg,R. and Tanaka,K.
TITLE Molecular cloning and nucleotide sequence of cDNAs encoding human
long-chain acyl-CoA dehydrogenase and assignment of the location of
its gene (ACADL) to chromosome 2
JOURNAL Genomics 11 (3), 609-620 (1991)
PUBMED 1774065
COMMENT Original source text: Homo sapiens skin cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2217
/db_xref="H-InvDB:HIT000196305"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="2q34-q35"
/cell_type="fibroblast"
/tissue_type="skin"
gene 1..2217
/gene="ACADL"
CDS 6..1298
/gene="ACADL"
/EC_number="1.3.99.3"
/codon_start=1
/product="long chain acyl-CoA dehydrogenase"
/protein_id="AAA51565.1"
/db_xref="GDB:G00-118-745"
/translation="MAARLLRGSLRVLGGHRAPRQLPAARCSHSGGEERLETPSAKKL
TDIGIRRIFSPEHDIFRKSVRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVN
IAEHLGGIGGDLYSAAIVWEEQAYSNCSGPGFSIHSGIVMSYITNHGSEEQIKHFIPQ
MTAGKCIGAIAMTEPGAGSDLQGIKTNAKKDGSDWILNGSKVFISNGSLSDVVIVVAV
TNHEAPSPAHGISLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALLGE
ENKGFYYIMKELPQERLLIADVAISASEFMFEETRNYVKQRKAFGKTVAHLQTVQHKL
AELKTHICVTRAFVDNCLQLHEAKRLDSATACMAKYWASELQNSVAYDCVQLHGGWGY
MWEYPIAKAYVDARVQPIYGGTNEIMKELIAREIVFDK"
sig_peptide 6..95
/gene="ACADL"
/note="G00-118-745"
mat_peptide 96..1295
/gene="ACADL"
/product="long chain acyl-CoA dehydrogenase"
/EC_number="1.3.99.3"
/note="G00-118-745"
BASE COUNT 732 a 409 c 468 g 608 t
ORIGIN chromosome 2, map position q34-q35.
1 cggacatggc cgcacgcctt ctccgagggt ccctacgcgt cctgggcggc caccgtgcgc
61 cgcgccagct gcccgccgcg cgatgttctc attccggagg ggaagaacgt ctagaaactc
121 cttctgctaa aaaattaaca gatataggaa ttcgaagaat cttttctcca gagcatgaca
181 ttttccggaa aagtgtaagg aagtttttcc aagaagaagt gattcctcat cactcagaat
241 gggagaaagc tggagaagta agtagggagg tttgggaaaa agctggaaaa caaggactgc
301 ttggtgtcaa tattgcagag catcttggtg gaattggagg ggatctgtac tccgcagcta
361 ttgtctggga ggagcaagct tattcaaatt gttcaggccc aggttttagt attcattcag
421 gtattgtcat gtcctatatt acaaaccatg gctcagaaga acagattaag cactttattc
481 cccagatgac tgcaggcaaa tgtattggtg caatagcaat gacagagcct ggagctggaa
541 gtgacttaca gggaataaaa acaaatgcta aaaaggatgg aagtgactgg attctcaatg
601 gaagcaaggt gttcatcagt aatgggtcat taagtgatgt tgtgattgta gttgcggtca
661 caaatcatga agctccctcc cctgcccatg gtattagcct ttttctggtg gaaaatggaa
721 tgaaaggatt tatcaaggga cgaaagctac ataaaatggg attaaaagcc caggataccg
781 cagaactatt ctttgaagat atacggttgc cagctagtgc cctacttgga gaagagaata
841 aaggcttcta ttacatcatg aaagagcttc cacaggaaag gctgttaatt gctgatgtgg
901 caatttcagc tagtgaattc atgtttgaag aaaccaggaa ctatgttaaa caaagaaaag
961 cttttggcaa aacagttgct cacctacaga cagtgcaaca taaattagca gaattaaaaa
1021 cacatatatg tgtaacccga gcatttgtgg acaactgtct ccagctgcat gaagcgaaac
1081 gtttggactc cgccactgct tgcatggcga aatattgggc atctgagtta caaaatagtg
1141 tagcttacga ctgtgtacag ctccatggag gttggggata catgtgggag tacccaattg
1201 caaaagctta tgtggatgcc agagttcagc caatctatgg tggtacaaat gaaataatga
1261 aggagctgat tgcaagagag attgtctttg acaagtagac atctgcccac atcctggagt
1321 cctattacag ctaatctcgt tttaaatctg ctcaagataa aatgtaactt ggaaagcgag
1381 gaaacactaa acatgttttt acctgctctc tctatagaga aggaaataaa atataaatat
1441 aagattaaca cagtggaagg acaaatcttt gaagccaaaa ttctagtttt ccaatataag
1501 gtttaactta cagtttttta tgtagccaaa ggtaaacggt tttctgaatc ttgcctaggt
1561 gtttcattta tctctaaaat tctaaaaagc ataaatcatt caaatcttca aaccaaggca
1621 gaaataattt tatgtcgcta tagtataaaa acattaataa gatagcacat tgacttttaa
1681 agggaaaagt aaatataact tagcatgtaa actcatttcg gctaccattt gctccaaatt
1741 ccctagaaca gtggttttta ccactgtact ccaaccccgt ttttaagcaa tggaactctt
1801 tcttcaaaca aaagcttatg cagaacatct ctgtgaaacg ctgctgagtg agaactgctt
1861 tcattgaagc tggaagccat cataccttac tgccttgaaa cccctaggac tcagctaagt
1921 atttgcctaa ccctgaccag ggaatgcctt ggttctgtca attgctgaca tctgagaaca
1981 cagaataatc catcattttt aatttcaaga tattggtaca ttttataggt atcaaagcaa
2041 tggcttttct tttgcaacag ttaatgtatt tattaactta ataattactt tatgtcttct
2101 ataaaccagg ctgttaatac aatgatgaca aacaaaactg gcaagatcac taaaaaataa
2161 gtgaataaac aaataagtag taaaataagg taagaagtaa atatgtaaaa gagataa
//