LOCUS HUMFAPTB2 2261 bp mRNA linear HUM 15-MAY-1995
DEFINITION Human TB2 gene mRNA, 3' end.
ACCESSION M74090
VERSION M74090.1
KEYWORDS FAP.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2261)
AUTHORS Kinzler,K.W., Nilbert,M.C., Su,L.K., Vogelstein,B., Bryan,T.M.,
Levy,D.B., Smith,K.J., Preisinger,A.C., Hedge,P., McKechnie,D.,
Finniear,R., Markham,A., Groffen,J., Boguski,M.S., Altschul,S.F.,
Horii,A.K., Ando,H., Miyoshi,Y., Miki,Y., Nishisho,I. and
Nakamura,Y.
TITLE Identification of FAP locus genes from chromosome 5q21
JOURNAL Science 253 (5020), 661-665 (1991)
PUBMED 1651562
REFERENCE 2 (sites)
AUTHORS Nishisho,I., Nakamura,Y., Miyoshi,Y., Miki,Y., Ando,H., Horii,A.,
Koyama,K., Utsunomiya,J., Baba,S. and Hedge,P.
TITLE Mutations of chromosome 5q21 genes in FAP and colorectal cancer
patients
JOURNAL Science 253 (5020), 665-669 (1991)
PUBMED 1651563
REFERENCE 3 (bases 1 to 2261)
AUTHORS Kinzler,K.W.
TITLE Direct Submission
JOURNAL Submitted (31-JUL-1991) K.W. Kinzler, Molecular Genetics
Laboratory, Johns Hopkins University School of Medicine, Baltimore,
MD 21231 USA
COMMENT On May 15, 1995 this sequence version replaced gi:182402.
Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2261
/db_xref="H-InvDB:HIT000196301"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="5q21"
gene 1..2261
/gene="TB2"
CDS <1..596
/gene="TB2"
/codon_start=3
/protein_id="AAA66351.1"
/translation="PSGETVPAMSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSF
IALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYG
VFSIAEFFSDIFLSWFPFYYILKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQM
DSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST"
BASE COUNT 677 a 441 c 459 g 684 t
ORIGIN
1 ccccgagcgg cgagacggtc cccgccatgt ctgcggccat gagggagagg ttcgaccggt
61 tcctgcacga gaagaactgc atgactgacc ttctggccaa gctcgaggcc aaaaccggcg
121 tgaacaggag cttcatcgct cttggtgtca tcggactggt ggccttgtac ctggtgttcg
181 gttatggagc ctctctcctc tgcaacctga taggatttgg ctacccagcc tacatctcaa
241 ttaaagctat agagagtccc aacaaagaag atgataccca gtggctgacc tactgggtag
301 tgtatggtgt gttcagcatt gctgaattct tctctgatat cttcctgtca tggttcccct
361 tctactacat actgaagtgt ggcttcctgt tgtggtgcat ggccccgagc ccttctaatg
421 gggctgaact gctctacaag cgcatcatcc gtcctttctt cctgaagcac gagtcccaga
481 tggacagtgt ggtcaaggac cttaaagaca aggccaaaga gactgcagat gccatcacta
541 aagaagcgaa gaaagctacc gtgaatttac tgggtgaaga aaagaagagc acctaaacca
601 gactggatgg aaacttcctg ccctctctgt accttcctac tggagcttga tgttatatta
661 gggactgtgg tataattatt ttaataatgt tgccttggaa acatttttga gatattaaag
721 attggaatgt gttgtaagtt tctttgctta cttttactgt ctatatatat agggagcact
781 ttaaacttaa tgcagtgggc agtgtccacg tttttggaaa atgtattttg cctctgggta
841 ggaaaagatg tatgttgcta tcctgcagga aatataaact taaaataaaa ttatataccc
901 cacaggctgt gtactttact gggctctccc tgcacgcatt ttctctgtag ttacatttag
961 gataatcttt atggttctac ttcctataat gtacaatttt atataattct gaaatgtttt
1021 taatgtattt gtgcacatgt acatatggaa atgttactgt ctgactacaa catgcatcat
1081 gctcatgggg agggagcagg ggaaggttgt atgtgtcatt tataacttct gtacagtaag
1141 accacctgcc aaaagctgga ggaaccattg tgctggtgtg gtctactaaa taatacttta
1201 ggaaatacgt gattaatatg caagtgaaca aagtgagaaa tgaaatcgaa tggagattgg
1261 cctggttgtt tccctagtat atggcatatg aataccagga tagctttata aagcagttag
1321 ttagttactc actctagtga taaatcggga aatttacaca cacacacaca cacacacaca
1381 cacagagtaa cctgtaactc tcaattccct gaaaaactag taatactgtc ttatctgcta
1441 taaactttac atatttgtct attgtcaaga tgctacaatg gaaaccattt ctggttttat
1501 cttcaaagcg gagaaacatg ttgatttagt cttctttccc aatcttcttt tttaaaccag
1561 tttaaggaac ttctgaagat ttgtccacct ctgattacat gtatgttctt gtttgtatca
1621 ttagcaacaa catgctaatg acgacaccta gctctaagag caattctggg agaatgaaag
1681 gaagtataaa gtaacccata atctgcttgg caatagttaa gtcaatctat cttcagtttt
1741 tctctggcct ttgaggtcaa acacaagagg cttccctagt ttacaagtca gagtcacttg
1801 tagtccattt aaatgccctc atccgtattc tttgtgttga taagctgcac atgactacat
1861 agtaagtaca gaacagtaaa gttaaaacgg atgtctccat tgatctgcca aatcgttata
1921 gagagcaatt tgtctggact agaaaatctg agttttacac catactgtta agagtccttt
1981 tgaattaaac tagactaaaa caagtgtata actaaactaa caagattaaa tatccagcca
2041 gtgcagtatt ttttaaggca aataaagatg attagctcac cttgagataa caatcaggta
2101 agatcataac aatgtctcat gatgtaaaaa atattaaaga tatcaatact aagtgacagt
2161 atcactctaa tataatatgg atcagagcat ttattttggg gaggaaaaca gtggtgatta
2221 ccggcatttt attaaactta aaactttgta gaaagcaaac c
//