LOCUS HUMSRDA 2437 bp mRNA linear HUM 13-JAN-1995
DEFINITION Human steroid 5-alpha-reductase 2 (SRD5A2) mRNA, complete cds.
ACCESSION M74047
VERSION M74047.1
KEYWORDS androgen; dihydrotestosterone; steroid 5-alpha-reductase 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2437)
AUTHORS Andersson,S., Berman,D.M., Jenkins,E.P. and Russell,D.W.
TITLE Deletion of steroid 5 alpha-reductase 2 gene in male
pseudohermaphroditism
JOURNAL Nature 354 (6349), 159-161 (1991)
PUBMED 1944596
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2437
/db_xref="H-InvDB:HIT000196297"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
gene 1..2437
/gene="SRD5A2"
CDS 28..792
/gene="SRD5A2"
/EC_number="1.3.99.5"
/codon_start=1
/product="steroid 5-alpha-reductase 2"
/protein_id="AAA60586.1"
/db_xref="GDB:G00-127-343"
/translation="MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLKPAA
TRLPARAAWFLQELPSFAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLN
RGRPYPAILILRGTAFCTGNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGIN
IHSDYILRQLRKPGEISYRIPQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAF
FSLCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF"
polyA_site 2437
/gene="SRD5A2"
/note="G00-127-343"
BASE COUNT 673 a 557 c 531 g 676 t
ORIGIN
1 gcggccaccg gcgaggaaca cggcgcgatg caggttcagt gccagcagag cccagtgctg
61 gcaggcagcg ccactttggt cgcccttggg gcactggcct tgtacgtcgc gaagccctcc
121 ggctacggga agcacacgga gagcctgaag ccggcggcta cccgcctgcc agcccgcgcc
181 gcctggttcc tgcaggagct gccttccttc gcggtgcccg cggggatcct cgcccggcag
241 cccctctccc tcttcgggcc acctgggacg gtacttctgg gcctcttctg cgtacattac
301 ttccacagga catttgtgta ctcactgctc aatcgaggga ggccttatcc agctatactc
361 attctcagag gcactgcctt ctgcactgga aatggagtcc ttcaaggcta ctatctgatt
421 tactgtgctg aataccctga tgggtggtac acagacatac ggtttagctt gggtgtcttc
481 ttatttattt tgggaatggg aataaacatt catagtgact atatattgcg ccagctcagg
541 aagcctggag aaatcagcta caggattcca caaggtggct tgtttacgta tgtttctgga
601 gccaatttcc tcggtgagat cattgaatgg atcggctatg ccctggccac ttggtccctc
661 ccagcacttg catttgcatt tttctcactt tgtttccttg ggctgcgagc ttttcaccac
721 cataggttct acctcaagat gtttgaggac taccccaaat ctcggaaagc ccttattcca
781 ttcatctttt aaaggaacca aattaaaaag gagcagagct cccacaatgc tgatgaaaac
841 tgtcaagctg ctgaaactgt aattttcatg atataatagt catatatata tatatatata
901 tatatatata tatatatatg tatatatgta atagtaggtc tcctggcgtt ctgccagctg
961 gcctggggat tctgagtggt gtctgcttag agtttactcc tacccttcca gggaccccta
1021 tcctgatccc caactgaagc ttcaaaaagc cacttttcca aatggcgaca gttgcttctt
1081 agctattgct ctgagaaagt acaaacttct cctatgtctt tcaccgggca atccaagtac
1141 atgtggcttc atacccactc cctgtcaatg caggacaact ctgtaatcaa gaattttttg
1201 acttgaaggc agtacttata gaccttatta aaggtatgca ttttatacat gtaacagagt
1261 agcagaaatt taaactctga agccacaaag acccagagca aacccactcc caaatgaaaa
1321 ccccagtcat ggcttccttt ttcttggtta attaggaaag atgagaaatt attaggtaga
1381 ccttgaatac aggagccctc tcctcatagt gctgaaaaga tactgatgca ttgacctcat
1441 ttcaaatttg tgcagtgtct tagttgatga gtgcctctgt tttccagaag atttcacaat
1501 ccccggaaaa ctggtatggc tattcttgaa ggccaggttt taataaccac aaacaaaaag
1561 gcatgaacct gggtggctta tgagagagta gagaacaaca tgaccctgga tggctactaa
1621 gaggatagag aacagtttta caatagacat tgcaaactct catgtttttg gaaactggtg
1681 gcaatatcca aataatgagt agtgtaaaac aaagagaatt aatgatgagg ttacatgctg
1741 cttgcctcca ccagatgtcc acaacaatat gaagtacagc agaagcccca agcaactttc
1801 ctttcctgga gcttcttcct tgtagttctc aggacctgtt caagaaggtg tctcctaggg
1861 gcagcctgaa tgcctccctc aaaggacctg caggcagaga ctgaaaattg cagacagagg
1921 ggcacgtctg ggcagaaaac ctgttttgtt tggctcagac atatagtttt ttttttttta
1981 caaagtttca aaaacttaaa aatcaggaga ttccttcata aaactctagc attctagttt
2041 catttaaaaa gttggaggat ctgaacatac agagcccaca tttccacacc agaactggaa
2101 ctacgtagct agtaagcatt tgagtttgca aactcttgtg aaggggtcac cccagcatga
2161 gtgctgagat atggactctc taaggaaggg gccgaacgct tgtaattgga atacatggaa
2221 atatttgtct tctcaggcct atgtttgcgg aatgcattgt caatatttag caaactgttt
2281 tgacaaatga gcaccagtgg tactaagcac agaaactcac tatataagtc acataggaaa
2341 cttgaaaggt ctgaggatga tgtagattac tgaaaaatac aaattgcaat catataaata
2401 agtgtttttg ttgttcatta aataccttta aatcatg
//