LOCUS HUMASF 1717 bp mRNA linear HUM 27-APR-1993
DEFINITION Human alternative splicing factor mRNA, complete cds.
ACCESSION M72709
VERSION M72709.1
KEYWORDS alternative splicing factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1717)
AUTHORS Ge,H., Zuo,P. and Manley,J.L.
TITLE Primary structure of the human splicing factor ASF reveals
similarities with Drosophila regulators
JOURNAL Cell 66 (2), 373-382 (1991)
PUBMED 1855257
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1717
/db_xref="H-InvDB:HIT000196253"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
mRNA join(1..648,831..1717)
/note="alternative"
mRNA join(1..648,848..1717)
/note="alternative"
exon 1..648
/number=1
5'UTR 1..96
CDS join(97..648,831..1157)
/note="alternative"
/number=2
/codon_start=1
/protein_id="AAA35564.1"
/translation="MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRD
IDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGG
GGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVV
EFVRKEDMTYAVRKLDNTKFRSHEFCLSNREKLPTSGLKLMGPEVQVMEDLDLEAVVV
AEAVAEATAGVAVTPQGEAEDHHAILPVIADLALVHKMIGDTFCRTHVVYSFPLFSTI
FSFFNSNCFVQNGLKC"
CDS join(97..648,848..1042)
/note="alternative"
/number=1
/codon_start=1
/protein_id="AAA35565.1"
/translation="MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRD
IDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGG
GGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVV
EFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSR
SNSRSRSYSPRRSRGSPRYSPRHSRSRSRT"
intron 649..847
/note="label: 1a"
/number=1
intron 649..830
/note="label: 1b"
/number=1
exon 831..1717
/note="label: 2b"
/number=2
exon 848..1717
/note="label: 2a"
/number=2
3'UTR 1043..1717
BASE COUNT 420 a 343 c 465 g 489 t
ORIGIN
1 cgccgcggga gacgtggtgc cgctgcgggc tcgctctgcc gtgcgctagg cttggtggga
61 aggcctgttc tcgagtccgc acttttcgtc accgccatgt cgggaggtgg tgtgattcgt
121 ggccccgcag ggaacaacga ttgccgcatc tacgtgggta acttacctcc agacatccga
181 accaaggaca ttgaggacgt gttctacaaa tacggcgcta tccgcgacat cgacctcaag
241 aatcgccgcg ggggaccgcc cttcgccttc gttgagttcg aggacccgcg agacgcagag
301 gacgcggtgt atggtcgcga cggctatgat tacgatgggt accgtctgcg ggtggagttt
361 cctcgaagcg gccgtggaac aggccgaggc ggcggcgggg gtggaggtgg cggagctccc
421 cgaggtcgct atggcccccc atccaggcgg tctgaaaaca gagtggttgt ctctggactg
481 cctccaagtg gaagttggca ggatttaaag gatcacatgc gtgaagcagg tgatgtatgt
541 tatgctgatg tttaccgaga tggcactggt gtcgtggagt ttgtacggaa agaagatatg
601 acctatgcag ttcgaaaact ggataacact aagtttagat ctcatgaggt aggttataca
661 cgtattcttt tctttgacca gaattggata cagtggtctt aacagtggaa tttcaaggta
721 aggattcagg caaggttgtc aagtaaattg ccagatttct ggttttagtt acattgtatt
781 acttacgcat gtctgaagat agatgaaagc ttagatcttt caatggaaag ttctgtctat
841 ccaataggga gaaactgcct acatccgggt taaagttgat gggcccagaa gtccaagtta
901 tggaagatct cgatctcgaa gccgtagtcg tagcagaagc cgtagcagaa gcaacagcag
961 gagtcgcagt tactccccaa ggagaagcag aggatcacca cgctattctc cccgtcatag
1021 cagatctcgc tctcgtacat aagatgattg gtgacacttt ttgtagaacc catgttgtat
1081 acagttttcc tttattcagt acaatctttt cattttttaa ttcaaactgt tttgttcaga
1141 atgggctaaa gtgttgaatt gcattcttgt aatatcccct tgctcctaac atctacattc
1201 ccttcgtgtc tttgataaat tgtattttaa gtgatgtcat agacaggatt gtttaaattt
1261 agttaactcc atactcttca gactgtgata ttgtgtaaat gtctatctgc cctggtttgt
1321 gtgaactggg atgttggggt gtttgtggtt atcttacctg ggaagttctt agtttatctt
1381 gcttttcatg tgtctttctg tagacatatc tgaagagatg gattaagaat gctttggatt
1441 aaggattgtg gagcacattt caatcatttt aggattgtca aaaggaggat tgaggaggat
1501 cagatcaata atggaggcaa tggtttggat tggagagggc tcactggatc ccaatccttg
1561 gagctggatc attggattca aatcataatg tggataggat agggaggatg aattaccagg
1621 attcatggag cgggatcaga ttaccaggaa cataggagtg gattcctgcc ccaaccaaac
1681 cgcattcgtg tggatttttt tattcaactt aattggc
//