LOCUS HUMIGFR1PR 1651 bp DNA linear HUM 08-NOV-1994
DEFINITION Human insulin-like growth factor I receptor gene, promoter region
and 5' end.
ACCESSION M69229
VERSION M69229.1
KEYWORDS insulin-like growth factor I receptor promoter region.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1651)
AUTHORS Cooke,D.W., Bankert,L.A., Roberts,C.T. Jr., LeRoith,D. and
Casella,S.J.
TITLE Analysis of the human type I insulin-like growth factor receptor
promoter region
JOURNAL Biochem. Biophys. Res. Commun. 177 (3), 1113-1120 (1991)
PUBMED 1711844
FEATURES Location/Qualifiers
source 1..1651
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/map="15q25-qter"
old_sequence 240
/citation=[1]
/replace="g"
old_sequence 278
/citation=[1]
/replace="c"
old_sequence 370..399
/citation=[1]
/replace="ctccgcacgtcttggggaacccgggctccg"
5'UTR 518..1557
old_sequence 908
/citation=[1]
/replace="g"
old_sequence 914
/citation=[1]
/replace="a"
old_sequence 963
/citation=[1]
/replace="c"
old_sequence 1526
/note="extra t deleted"
/citation=[1]
/replace="t"
old_sequence 1537
/citation=[1]
/replace="a"
gene 1558..1647
/gene="IGF1R"
CDS 1558..1647
/gene="IGF1R"
/codon_start=1
/protein_id="AAB59399.1"
/db_xref="GDB:G00-120-082"
/translation="MKSGSGGGSPTSLWGLLFLSAALSLWPTSG"
sig_peptide 1558..1647
/gene="IGF1R"
/note="G00-120-082"
mat_peptide 1639..1647
/gene="IGF1R"
/product="G00-120-082"
BASE COUNT 188 a 572 c 598 g 293 t
ORIGIN
1 aagcttttca agaaccgggg aaacgcgctt tccagccgcg ctgttgttgt tttcaatgaa
61 cctctcccag ccccgcactc cccgcccacc cctcccctct cctgcccacc cctcccctct
121 cctgcccacc cctcccctgc ctagcctttc cctggctacc cacccctgcc ccgccgagac
181 cggaccggcg gcgggggcat tgtttttgga gtcgggcggg aggggagggc gcgtgcgggg
241 tggccggcgc agtgcggtgg gggcgggagc gggtgggcac gcgcgcgtgt ctctgtgtgc
301 gcgcgggagg cggtggggcg ggagatgggg gcggcgcctc gcagtctcgc gccccacgcc
361 cgggctccgc tccgcacgtc ttggggaacc cgggctccgg ttttttgcgc gcgccggcct
421 gggccgggcc ctcggcgcgc cgctgctcgg cggtggccgc tcgagtgtgc gagcgggcgc
481 gtgtgcgcgg gccagggcgc cgcgcgcgcg agcccccagt gtgtggcagc ggcggcggcg
541 gcgcggcgag gctggggctc ttgtttacca gcattaactc gctgagcgga aaaaaaaagg
601 gaaaaaaccc gaggaggagc gagcgcacca ggcgaactcg agagaggcgg gagagcgaga
661 gggacgccgc cagcgagcct gcccacggcc ggcgctcgca gaccctcggc cccgctcccc
721 ggatcccccc gcgccctcca cgcccctccc gcgcgggggc agctccacgg cgcgcctcgc
781 ctcggctgtg accttcagcg agccggagcc cccgcgcaga gcaggcggcg gcgggcgggg
841 gccgggcggg ggccggcgcg gggcgggcgg cggcgcagag ccgggcggcg cggcgggagt
901 gctgagcgcg gcgcggccgg cccgccgctt tgtgtgtgtc ctggatttgg gaaggagctc
961 gccgcggcgg cggcgctgag ggaggaggcg gcggcgagcg gagccaggag gaggaggagg
1021 aggaggggga gccgctcatt cattttgact ccgcgtttct gcccctcgcc ggcctcgcct
1081 gtgacccgga cttcggggcg atcttgcgaa ctgcgtcgcg ccctcccgcg gcggaagctc
1141 gggcgtccgg ccgcctcccg cgcgccaggg ccgggcttgt ttttcctcgc ctaggcagat
1201 ttgggctttg ccccctttct ttgcagtttt ccccccttcc tgcctctccg ggtttgaaaa
1261 tggaggccga cgacgccgac agcccgcccc ggcgcgcctc gggttcccga ctccgccgag
1321 ccctgggccg ctgctgccgg cgctgagggg ccgccccgcg ccgcccgccc cgtccgcgca
1381 cccggagggc cccggcggcg gcccttcgga gtattgtttc cttcgccctt gtttttggag
1441 ggggagcgaa gactgagttt gagacttgtt tcctttcatt tccttttttt cttttctttt
1501 cttttttttt tttttttttt tttttgagaa aggggaattt catcccaaat aaaaggaatg
1561 aagtctggct ccggaggagg gtccccgacc tcgctgtggg ggctcctgtt tctctccgcc
1621 gcgctctcgc tctggccgac gagtggagaa a
//