LOCUS HUMMYOHCB 7596 bp mRNA linear HUM 26-JUL-2016
DEFINITION Human nonmuscle myosin heavy chain-B (MYH10) mRNA, partial cds.
ACCESSION M69181
VERSION M69181.1
KEYWORDS Human non-muscle myosin B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 266 to 2245)
AUTHORS Simons,M., Wang,M., McBride,O.W., Kawamoto,S., Yamakawa,K.,
Gdula,D., Adelstein,R.S. and Weir,L.
TITLE Human nonmuscle myosin heavy chains are encoded by two genes
located on different chromosomes
JOURNAL Circ. Res. 69 (2), 530-539 (1991)
PUBMED 1860190
REFERENCE 2 (bases 1 to 7596)
AUTHORS Phillips,C.L., Yamakawa,K. and Adelstein,R.S.
TITLE Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B
and analysis of human tissues with isoform-specific antibodies
JOURNAL J. Muscle Res. Cell. Motil. 16 (4), 379-389 (1995)
PUBMED 7499478
REFERENCE 3 (bases 1 to 7596)
AUTHORS Adelstein,R.S.
TITLE Direct Submission
JOURNAL Submitted (04-MAR-1994) R.A. Adelstein, National Institutes of
Health, NHLBI, 9000 Rockville Pike, Bethesda, Md 20892, USA
COMMENT On Jan 30, 1995 this sequence version replaced gi:189031.
FEATURES Location/Qualifiers
source 1..7596
/db_xref="H-InvDB:HIT000196222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat"
/cell_type="T lymphocyte"
/clone_lib="Lambda Zap II adult human T-cell library
(Jurkat cells)"
gene 1..7596
/gene="MYH10"
CDS 80..>6007
/gene="MYH10"
/experiment="experimental evidence, no additional details
recorded"
/note="Between nucleotides 1942-1943 in mRNA encoding
human brain MHC-B there is an alternatively spliced
sequence,
gagattcagaatattcagagagcttctttctatgacagtgtttctggtcttcatga
gccacca"
/citation=[2]
/codon_start=1
/product="non-muscle myosin B"
/protein_id="AAA99177.1"
/db_xref="GDB:G00-127-350"
/translation="MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHG
FEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVL
HNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISES
AYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQL
LQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAK
DERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMH
IMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEF
TRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQ
GASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF
IDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKP
RQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR
IVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPN
HEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGF
MDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCR
GCLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQA
KDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLA
AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE
KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN
KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK
EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSE
ELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATA
LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQ
ELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT
QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK
KVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL
DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEE
ALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE
DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERK
QRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASR
DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSA
LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD
NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANK
LVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR
RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDD
DTESKTSDVNETQPPQSE"
BASE COUNT 2283 a 1697 c 2021 g 1595 t
ORIGIN
1 gtggtcgcgg ctggggacgt gcgcccgcgc caccatcttc ggctgaagag gcaattgctt
61 ttggatcgtt ccatttacaa tggcgcagag aactggactc gaggatccag agaggtatct
121 ctttgtggac agggctgtca tctacaaccc tgccactcaa gctgattgga cagctaaaaa
181 gctagtgtgg attccatcag aacgccatgg ttttgaggca gctagtatca aagaagaacg
241 gggagatgaa gttatggtgg agttggcaga gaatggaaag aaagcaatgg tcaacaaaga
301 tgatattcag aagatgaacc cacctaagtt ttccaaggtg gaggatatgg cagaattgac
361 atgcttgaat gaagcttccg ttttacataa tctgaaggat cgctactatt caggactaat
421 ctatacttat tctggactct tctgtgtagt tataaaccct tacaagaatc ttccaattta
481 ctctgagaat attattgaaa tgtacagagg gaagaagcgt catgagatgc ctccacacat
541 ctatgctata tctgaatctg cttacagatg catgcttcaa gatcgtgagg accagtcaat
601 tctttgcacg ggtgagtcag gtgctgggaa gacagaaaat acaaagaaag ttattcagta
661 ccttgcccat gttgcttctt cacataaagg aagaaaggac cataatattc ctggggaact
721 tgaacggcag cttttgcaag caaatccaat tctcgaatca tttggaaatg cgaagactgt
781 gaaaaatgat aactcatctc gttttggcaa atttattcgg atcaactttg atgtaactgg
841 ctatatcgtt ggggccaaca ttgaaacata ccttctggaa aagtctcgtg ctgttcgtca
901 agcaaaagat gaacgtactt ttcatatctt ttaccagttg ttatctggag caggagaaca
961 cctaaagtct gatttgcttc ttgaaggatt taataactac aggtttctct ccaatggcta
1021 tattcctatt ccgggacagc aagacaaaga taatttccag gagaccatgg aagcaatgca
1081 cataatgggc ttctcccatg aagagattct gtcaatgctt aaagtagtat cttcagtgct
1141 acagtttgga aatatttctt tcaaaaagga gagaaatact gatcaagctt ccatgccaga
1201 aaatacagtt gcgcagaagc tctgccatct tcttgggatg aatgtgatgg agtttactcg
1261 ggccatcctg actccccgga tcaaggtcgg ccgagactat gtgcaaaaag cccagaccaa
1321 agaacaggca gattttgcag tagaagcatt ggcaaaagct acctatgagc ggctctttcg
1381 ctggctcgtt catcgcatca ataaagctct ggataggacc aaacgtcagg gagcatcttt
1441 cattggaatc ctggatattg ctggatttga aatttttgag ctgaactcct ttgaacaact
1501 ttgcatcaac tacaccaatg agaagctgca gcagctgttc aaccacacca tgtttatcct
1561 agaacaagag gaataccagc gcgaaggcat cgagtggaac ttcatcgatt tcgggctgga
1621 tctgcagcca tgcatcgacc taatagagag acctgcgaac cctcctggtg tactggccct
1681 tttggatgaa gaatgctggt tccctaaagc cacagataaa acctttgttg aaaaactggt
1741 tcaagagcaa ggttcccact ccaagtttca gaaacctcga caattaaaag acaaagctga
1801 tttttgcatt atacattatg cagggaaggt ggactataag gcagatgagt ggctgatgaa
1861 gaatatggac cccctgaatg acaacgtggc cacccttttg caccagtcat cagacagatt
1921 tgtggcagag ctttggaaag atgtggaccg tatcgtgggt ctggatcaag tcactggtat
1981 gactgagaca gcttttggct ccgcatataa aaccaagaag ggcatgtttc gtaccgttgg
2041 gcaactctac aaagaatctc tcaccaagct gatggcaact ctccgaaaca ccaaccctaa
2101 ctttgttcgt tgtatcattc caaatcacga gaagagggct ggaaaattgg atccacacct
2161 agtcctagat cagcttcgct gtaatggtgt cctggaaggg atccgaatct gtcgccaggg
2221 cttccctaac cgaatagttt tccaggaatt cagacagaga tatgagatcc taactccaaa
2281 tgctattcct aaaggtttta tggatggtaa acaggcctgt gaacgaatga tccgggcttt
2341 agaattggac ccaaacttgt acagaattgg acagagcaag atatttttca gagctggagt
2401 tctggcacac ttagaggaag aaagagattt aaaaatcacc gatatcatta tcttcttcca
2461 ggccgtttgc agaggttgcc tggccagaaa ggcctttgcc aagaagcagc agcaactaag
2521 tgccttaaag gtcttgcagc ggaactgtgc cgcgtacctg aaattacggc actggcagtg
2581 gtggcgagtc ttcacaaagg tgaagccgct tctacaagtg actcgccagg aggaagaact
2641 tcaggccaaa gatgaagagc tgttgaaggt gaaggagaag cagacaaagg tggaaggaga
2701 gctggaggag atggagcgga agcaccagca gcttttagaa gagaagaata tccttgcaga
2761 acaactacaa gcagagactg agctctttgc tgaagcagaa gagatgaggg caagacttgc
2821 tgctaaaaag caggaattag aagagattct acatgacttg gagtctaggg ttgaagaaga
2881 agaagaaaga aaccaaatcc tccaaaatga aaagaaaaaa atgcaagcac atattcagga
2941 cctggaagaa cagctagacg aggaggaagg ggctcggcaa aagctgcagc tggaaaaggt
3001 gacagcagag gccaagatca agaagatgga agaggagatt ctgcttctcg aggaccaaaa
3061 ttccaagttc atcaaagaaa agaaactcat ggaagatcgc attgctgagt gttcctctca
3121 gctggctgaa gaggaagaaa aggcgaaaaa cttggccaaa atcaggaata agcaagaagt
3181 gatgatctca gatttagaag aacgcttaaa gaaggaagaa aagactcgtc aggaactgga
3241 aaaggccaaa agaaaactcg acggggagac gaccgacctg caggaccaga tcgcagagct
3301 gcaggcgcag attgatgagc tcaagctgca gctggccaag aaggaggagg agctgcaggg
3361 cgcactggcc agaggtgatg atgaaacact ccataagaac aatgccctta aagttgtgcg
3421 agagctacaa gcccaaattg ctgaacttca ggaagacttt gaatccgaga aggcttcacg
3481 gaacaaggcc gaaaagcaga aaagggactt gagtgaggaa ctggaagctc tgaaaacaga
3541 gctggaggac acgctggaca ccacggcagc ccagcaggaa ctacgtacaa aacgtgaaca
3601 agaagtggca gagctgaaga aagctcttga ggaggaaact aagaaccatg aagctcaaat
3661 ccaggacatg agacaaagac acgcaacagc cctggaggag ctctcagagc agctggaaca
3721 ggccaagcgg ttcaaagcaa atctagagaa gaacaagcag ggcctggaga cagataacaa
3781 ggagctggcg tgtgaggtga aggtcctgca gcaggtcaag gctgagtctg agcacaagag
3841 gaagaagctc gacgcgcagg tccaggagct ccatgccaag gtctctgaag gcgacaggct
3901 cagggtggag ctggcggaga aagcaagtaa gctgcagaat gagctagata atgtctccac
3961 ccttctggaa gaagcagaga agaagggtat taaatttgct aaggatgcag ctagtcttga
4021 gtctcaacta caggatacac aggagcttct tcaggaggag acacgccaga aactaaacct
4081 gagcagtcgg atccggcagc tggaagagga gaagaacagt cttcaggagc agcaggagga
4141 ggaggaggag gccaggaaga acctggagaa gcaagtgctg gccctgcagt cccagttggc
4201 tgataccaag aagaaagtag atgacgacct gggaacaatt gaaagtctgg aagaagccaa
4261 gaagaagctt ctgaaggacg cggaggccct gagccagcgc ctggaggaga aggcactggc
4321 gtatgacaaa ctggagaaga ccaagaaccg cctgcagcag gagctggacg acctcacggt
4381 ggacctggac caccagcgcc aggtcgcctc caacttggag aagaagcaga agaagtttga
4441 ccagctgtta gcagaagaga agagcatctc tgctcgctat gccgaagagc gggaccgggc
4501 cgaagccgag gccagagaga aagaaaccaa agccctgtca ctggcccggg ccctcgagga
4561 agccctggag gccaaggagg agtttgagag gcagaacaag cagctccgag cagacatgga
4621 agacctcatg agctccaaag atgatgtggg aaaaaacgtt cacgaacttg aaaaatccaa
4681 acgggcccta gagcagcagg tggaggaaat gaggacccag ctggaggagc tggaagacga
4741 actccaggcc acggaagatg ccaagcttcg tctggaggtc aacatgcagg ccatgaaggc
4801 gcagttcgag agagacctgc aaaccaggga tgagcagaat gaagagaaga agcggctgct
4861 gatcaaacag gtgcgggagc tcgaggcgga gctggaggat gagaggaaac agcgggcgct
4921 tgctgtagct tcgaagaaaa agatggagat agacctgaag gacctcgaag cccaaatcga
4981 ggctgcgaac aaagctcggg atgaggtgat taagcagctc cgcaagctcc aggctcagat
5041 gaaggattac caacgtgaat tagaagaagc tcgtgcatcc agagatgaga tttttgctca
5101 atccaaagag agtgaaaaga aattgaagag tctggaagca gaaatccttc aattgcagga
5161 ggaacttgcc tcatctgagc gagcccgccg acacgccgag caggagagag atgagctggc
5221 ggacgagatc accaacagcg cctctggcaa gtccgcgctg ctggatgaga agcggcgtct
5281 ggaagctcgg atcgcacagc tggaggagga gctggaagag gagcagagca acatggagct
5341 gctcaacgac cgcttccgca agaccactct acaggtggac acactgaacg ccgagctagc
5401 agccgagcgc agcgccgccc agaagagtga caatgcacgc cagcaactgg agcggcagaa
5461 caaggagctg aaggccaagc tgcaggaact cgagggtgct gtcaagtcta agttcaaggc
5521 caccatctca gccctggagg ccaagattgg gcagctggag gagcagcttg agcaggaagc
5581 caaggaacga gcagccgcca acaaattagt ccgtcgcact gagaagaagc tgaaagaaat
5641 cttcatgcag gttgaggatg agcgtcgaca cgcggaccag tataaagagc agatggagaa
5701 ggccaacgct cggatgaagc agcttaaacg ccagctggag gaagcagaag aagaagcgac
5761 gcgtgccaac gcatctcggc gtaaactcca gcgggaactg gatgatgcca ccgaggccaa
5821 cgagggcctg agccgcgagg tcagcaccct gaagaaccgg ctgaggcggg gtggccccat
5881 cagcttctct tccagccgat ctggccggcg ccagctgcac cttgaaggag cttccctgga
5941 gctctccgac gatgacacag aaagtaagac cagtgatgtc aacgagacgc agccacccca
6001 gtcagagtaa agttgcagga agccagagga ggcaatacag tgggacagtt aggaatgcac
6061 ccggggcctc ctgcagattt cggaaattgg caagctacgg gattccttcc tgaaagatca
6121 actgtgtctt aaggctctcc agcctatgca tactgtatcc tgcttcagac ttaggtacaa
6181 ttgctcccct ttttatatac agacacacac aggacacata tattaaacag attgtttcat
6241 cattgcatct attttccata tagtcatcaa gagaccattt tataaaacat ggtaagaccc
6301 tttttaaaac aaactccagg cccttggttg cgggtcgctg ggttattggg gcagcgccgt
6361 ggtcgtcact cagtcgctct gcatgctctc tgtcatacag acaggtaacc tagttctgtg
6421 ttcacgtggc ccccgactcc tcagccacat caagtctcct agaccactgt ggactctaaa
6481 ctgcacttgt ctctctcatt tccttcaaat aatgatcaat gctatttcag tgagcaaact
6541 gtgaaagggg ctttggaaag agtaggaggg gtgggctgga tcggaagcaa cacccatttg
6601 gggttaccat gtccatcccc caaggggggc cctccccctc gagtcgatgg tgtcccgcat
6661 ctactcatgt gaactggcct tggcgagggc tggtctgtgc atagaaggga tagtggccac
6721 actgcagctg aggccccagg tggcagccat ggatcatgta gacttccaga tggtctcccg
6781 aaccgcctgg ctctgccggc gccctcctca cgtcaggagc aagcagccgt ggacccctaa
6841 gccgagctgg tggaaggccc ctccccgtcg ccagccgggc cctcatgctg accttgcaaa
6901 ttcagccgct gctttgagcc caaaatggga atattggttt tgtgtccgag gcttgttcca
6961 agtttgtcaa tgaggtttat ggagcctcca gaacagatgc catcttcctg aatgttgaca
7021 tgccagtggg tgtgactcct tcatttttcc ttctcccttc cctttggaca gtgttacagt
7081 gaacacttag catcctgttt ttggttggta gttaagcaaa ctgacattac ggaaagtgcc
7141 ttagacacta cagtactaag acaatgttga atatatcatt cgcctctata acaatttaat
7201 gtattcagtt ttgactgtgc ttcatatcat gtacctctct agtcaaagtg gtattacaga
7261 cattcagtga caatgaatca gtgttaattc taaatccttg atcctctgca atgtgcttga
7321 aaacacaaac cttttgggtt aaaagcttta acatctatta ggaagaattt gtcctgtggg
7381 tttggaatct tggattttcc ccctttatga actgtactgg ctgttgacca ccagacacct
7441 gaccgcaaat atcttttctt gtattcccat atttctagac aatgattttt gtaagacaat
7501 aaatttattc attatagata tttgcgcctg ctctgtttac ttgaagaaaa aagcacccgt
7561 ggagaataaa gagacctcaa taaacaaaaa aaaaaa
//