LOCUS HUMNKSFP40 2318 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human natural killer cell stimulatory factor (NKSF) mRNA, complete
cds, clone p40.
ACCESSION M65290
VERSION M65290.1
KEYWORDS cytokine; natural killer cell stimulatory factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2318)
AUTHORS Wolf,S.F., Temple,P.A., Kobayashi,M., Young,D., Dicig,M., Lowe,L.,
Dzialo,R., Fitz,L., Ferenz,C., Hewick,R.M., Kelleher,K.,
Herrmann,S.H., Clark,S.C., Azzoni,L., Chan,S.H., Trinchieri,G. and
Perussia,B.
TITLE Cloning of cDNA for natural killer cell stimulatory factor, a
heterodimeric cytokine with multiple biologic effects on T and
natural killer cells
JOURNAL J. Immunol. 146 (9), 3074-3081 (1991)
PUBMED 1673147
COMMENT Original source text: Human EBV-transformed B cell line RPMI 8866,
cDNA to mRNA, clone p40.
FEATURES Location/Qualifiers
source 1..2318
/db_xref="H-InvDB:HIT000196178"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/cell_line="EBV-transformed B cell line RPMI 8866"
gene 1..2318
/gene="NKSF2"
CDS 14..1000
/gene="NKSF2"
/codon_start=1
/product="natural killer cell stimulatory factor"
/protein_id="AAA59938.1"
/db_xref="GDB:G00-127-870"
/translation="MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGE
MVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLL
LLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSR
GSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKL
KYENYTSSFFIRDIIKPDPPNNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQ
VQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS"
sig_peptide 14..79
/gene="NKSF2"
/note="G00-127-870"
mat_peptide 80..997
/gene="NKSF2"
/product="natural killer cell stimulatory factor"
/note="G00-127-870"
BASE COUNT 692 a 478 c 535 g 613 t
ORIGIN
1 ggcccagagc aagatgtgtc accagcagtt ggtcatctct tggttttccc tggtttttct
61 ggcatctccc ctcgtggcca tatgggaact gaagaaagat gtttatgtcg tagaattgga
121 ttggtatccg gatgcccctg gagaaatggt ggtcctcacc tgtgacaccc ctgaagaaga
181 tggtatcacc tggaccttgg accagagcag tgaggtctta ggctctggca aaaccctgac
241 catccaagtc aaagagtttg gagatgctgg ccagtacacc tgtcacaaag gaggcgaggt
301 tctaagccat tcgctcctgc tgcttcacaa aaaggaagat ggaatttggt ccactgatat
361 tttaaaggac cagaaagaac ccaaaaataa gacctttcta agatgcgagg ccaagaatta
421 ttctggacgt ttcacctgct ggtggctgac gacaatcagt actgatttga cattcagtgt
481 caaaagcagc agaggctctt ctgaccccca aggggtgacg tgcggagctg ctacactctc
541 tgcagagaga gtcagagggg acaacaagga gtatgagtac tcagtggagt gccaggagga
601 cagtgcctgc ccagctgctg aggagagtct gcccattgag gtcatggtgg atgccgttca
661 caagctcaag tatgaaaact acaccagcag cttcttcatc agggacatca tcaaacctga
721 cccacccaac aacttgcagc tgaagccatt aaagaattct cggcaggtgg aggtcagctg
781 ggagtaccct gacacctgga gtactccaca ttcctacttc tccctgacat tctgcgttca
841 ggtccagggc aagagcaaga gagaaaagaa agatagagtc ttcaccgaca agacctcagc
901 cacggtcatc tgccgcaaaa atgccagcat tagcgtgcgg gcccaggacc gctactatag
961 ctcatcttgg agcgaatggg catctgtgcc ctgcagttag gttctgatcc aggatgaaaa
1021 tttggaggaa aagtggaaga tattaagcaa aatgtttaaa gacacaacgg aatagaccca
1081 aaaagataat ttctatctga tttgctttaa aacgtttttt taggatcaca atgatatctt
1141 tgctgtattt gtatagttcg atgctaaatg ctcattgaaa caatcagcta atttatgtat
1201 agattttcca gctctcaagt tgccatgggc cttcatgcta tttaaatatt taagtaattt
1261 atgtatttat tagtatatta ctgttattta acgtttgtct gccaggatgt atggaatgtt
1321 tcatactctt atgacctgat ccatcaggat cagtccctat tatgcaaaat gtgaatttaa
1381 ttttatttgt actgacaact tttcaagcaa ggctgcaagt acatcagttt tatgacaatc
1441 aggaagaatg cagtgttctg ataccagtgc catcatacac ttgtgatgga tgggaacgca
1501 agagatactt acatggaaac ctgacaatgc aaacctgttg agaagatcca ggagaacaag
1561 atgctagttc ccatgtctgt gaagacttcc tggagatggt gttgataaag caatttaggg
1621 ccacttacac ttctaagcaa gtttaatctt tggatgcctg aattttaaaa gggctagaaa
1681 aaaatgattg accagcctgg gaaacataac aagaccccgt ctctacaaaa aaaatttaaa
1741 attagccagg cgtggtggct catgcttgtg gtcccagctg ttcaggagga tgaggcagga
1801 ggatctcttg agcccaggag gtcaaggcta tggtgagccg tgattgtgcc actgcatacc
1861 agcctaggtg acagaatgag accctgtctc aaaaaaaaaa atgattgaaa ttaaaattca
1921 gctttagctt ccatggcagt cctcaccccc acctctctaa aagacacagg aggatgacac
1981 agaaacaccg taagtgtctg gaaggcaaaa agatcttaag attcaagaga gaggacaagt
2041 agttatggct aaggacatga aattgtcaga atggcaggtg gcttcttaac agccatgtga
2101 gaagcagaca gatgcaaaga aaatctggaa tccctttctc attagcatga atgaacctga
2161 tacacaatta tgaccagaaa atatggctcc atgaaggtgc tacttttaag taatgtatgt
2221 gcgctctgta aagtgattac atttgtttcc tgtttgttta tttatttatt tatttttgca
2281 ttctgaggct gaactaataa aaactcttct ttgtaatc
//