LOCUS HUMLCEA 1568 bp mRNA linear HUM 20-DEC-1995
DEFINITION Human liver carboxylesterase mRNA, 3' end.
ACCESSION M65261
VERSION M65261.1
KEYWORDS carboxylesterase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1568)
AUTHORS Riddles,P.W., Richards,L.J., Bowles,M.R. and Pond,S.M.
TITLE Cloning and analysis of a cDNA encoding a human liver
carboxylesterase
JOURNAL Gene 108 (2), 289-292 (1991)
PUBMED 1748313
COMMENT Original source text: Homo sapiens adult liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1568
/db_xref="H-InvDB:HIT000196175"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="16q13-q22.1"
/tissue_type="liver"
/dev_stage="adult"
/note="(vector lambda gt11)"
gene 1..1568
/gene="CES1"
CDS <1..1367
/gene="CES1"
/EC_number="3.1.1.1"
/codon_start=3
/product="carboxylesterase"
/protein_id="AAA83932.1"
/db_xref="GDB:G00-128-044"
/translation="EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLAL
AAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSV
TIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAG
CKTTTSAAMVHCLRQKTEEELLETTLKIGNSYLWTYRETQRESTLLGTVIDGMLLLKT
PEELQRERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLGSPIPLF
AIAKELIPEATEKYLGGTDDTVKKKDLILDLIADVMFGVPSVIVARNHRDAGAPTYMY
EFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFAR
NGNPNGKGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTD
HIEL"
BASE COUNT 400 a 365 c 455 g 348 t
ORIGIN
1 ctgaacactg tctttacctc aatatttaca ctcctgcaga cttgaccaag aaaaacaggc
61 tgccggtgat ggtgtggatc cacggagggg ggctgatggt gggtgcggca tcaacctatg
121 atgggctggc ccttgctgcc catgaaaacg tggtggtggt gaccattcaa tatcgcctgg
181 gcatctgggg attcttcagc acaggggatg aacacagccg ggggaactgg ggtcacctgg
241 accaggtggc tgccctgcgc tgggtccagg acaacattgc cagctttgga gggaacccag
301 gctctgtgac catctttgga gagtcagcgg gaggagaaag tgtctctgtt cttgttttgt
361 ctccattggc caagaacctc ttccaccggg ccatttctga gagtggcgtg gccctcactt
421 ctgttctggt gaagaaaggt gatgtcaagc ccttggctga gcaaattgct atcactgctg
481 ggtgcaaaac caccacctct gctgctatgg ttcactgcct gcgacagaag acggaagagg
541 agctcttgga gacgacattg aaaattggaa attcttatct ctggacttac agggagaccc
601 agagagagtc aacccttctg ggcactgtga ttgatgggat gctgctgctg aaaacacctg
661 aagagcttca acgtgaaagg aatttccaca ctgtccccta catggtcgga attaacaagc
721 aggagtttgg ctggttgatt ccaatgcagt tgatgagcta tccactctcc gaagggcaac
781 tggaccagaa gacagccatg tcactccttg gaagtcctat ccccttgttt gccattgcta
841 aggaactgat tccagaagcc actgagaaat acttaggagg aacagacgac actgtcaaaa
901 agaaagacct gatcctggac ttgatagcag atgtgatgtt tggtgtccca tctgtgattg
961 tggcccggaa ccacagagat gctggagcac ccacctacat gtatgagttt cagtaccgtc
1021 caagcttctc atcagacatg aaacccaaga cggtgatagg agaccacggg gatgagctct
1081 tctccgtctt tggggcccca tttttaaaag agggtgcctc agaagaggag atcagactta
1141 gcaagatggt gatgaaattc tgggccaact ttgctcgcaa tggaaacccc aatgggaaag
1201 ggctgcccca ctggccagag tacaaccaga aggaagggta tctgcagatt ggtgccaaca
1261 cccaggcggc ccagaagctg aaggacaaag aagtagcttt ctggaccaac ctctttgcca
1321 agaaggcagt ggagaagcca ccccagacag accacataga gctgtgatga gatccagccg
1381 gccttggagc tggacgagga gcaaagactg gggtcttttg cggaaaggga ttgcaggttc
1441 agaaggcatc ttacatgctg ggaatgtctg gtggtggggg caggggagag aggccgagag
1501 gccatgaagg aggcaagctt ttgtatttgt gacctcagcg tttgggaata aaggatcttt
1561 tgaaggcc
//