LOCUS HUMPROP2AA 2131 bp mRNA linear HUM 27-APR-1993
DEFINITION Human protein phosphatase 2A alpha subunit mRNA, complete cds.
ACCESSION M64929 J05328
VERSION M64929.1
KEYWORDS protein phosphatase-2A subunit-alpha; regulatory subunit.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2131)
AUTHORS Mayer,R.E., Hendrix,P., Cron,P., Matthies,R., Stone,S.R., Goris,J.,
Merlevede,W., Hofsteenge,J. and Hemmings,B.A.
TITLE Structure of the 55-kDa regulatory subunit of protein phosphatase
2A: evidence for a neuronal-specific isoform
JOURNAL Biochemistry 30 (15), 3589-3597 (1991)
PUBMED 1849734
COMMENT Original source text: Human lung fibroblast cell line WI38, cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..2131
/db_xref="H-InvDB:HIT000196151"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="WI38"
/cell_type="fibroblast"
/tissue_type="lung"
5'UTR 1..105
CDS 106..1449
/EC_number="3.1.3.16"
/note="55 kDa regulatory subunit"
/codon_start=1
/product="protein phosphatase-2A subunit-alpha"
/protein_id="AAA36490.1"
/translation="MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLA
TGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWL
PQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPM
DLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIK
PANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPS
NRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLC
SLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVL
KPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN"
3'UTR 1450..2131
BASE COUNT 665 a 421 c 460 g 585 t
ORIGIN
1 ccgccgccat ccgccctctc taccccccca tccccaggtg aggggggtga gttcaggaag
61 cggagacccc gaggaaccca gcagggtcac catttgcagc gcaacatggc aggagctgga
121 ggagggaatg atattcagtg gtgtttttct caggtgaaag gagcagtaga tgatgatgta
181 gcagaagcag atataatttc tacagtagaa tttaatcatt ctggagaatt actagcaaca
241 ggagataaag gtggtagagt tgtcatcttt caacaggagc aggagaacaa aatccagtct
301 catagcagag gagaatataa tgtttacagc accttccaga gccatgaacc agagtttgac
361 tacttgaaaa gtttagaaat agaagaaaag atcaataaaa ttaggtggtt accccagaaa
421 aatgctgctc agtttttatt gtctaccaat gataaaacaa taaaattatg gaaaatcagt
481 gaaagggaca aaagaccaga agggtataac ttgaaagagg aggatggaag gtatagagat
541 cctactacag ttactacact acgagtgcca gtctttaggc ctatggatct aatggttgag
601 gccagtccac gaagaatatt tgccaatgct catacatatc acatcaactc aatttctatt
661 aatagtgatt atgaaacata tttatctgca gatgatttgc ggattaatct ttggcatctg
721 gaaattacag acaggagttt taacattgtg gatatcaagc ctgccaatat ggaagagcta
781 acagaggtga ttacagcagc agaatttcat ccaaacagct gtaacacatt tgtatacagc
841 agcagtaaag gaactattcg gctatgtgac atgagggcat ctgccctctg tgatagacat
901 tctaaattgt ttgaagaacc tgaagatccc agtaacaggt catttttttc cgaaatcatc
961 tcctctattt cggatgtaaa attcagccat agtggtcgat atatgatgac tagagactat
1021 ttgtcagtca aaatttggga cttaaatatg gaaaacaggc ctgtggaaac ataccaggtg
1081 catgaatacc tcagaagtaa actctgttca ctgtatgaaa atgactgcat atttgacaaa
1141 tttgaatgtt gttggaatgg atctgacagt gttgtcatga ctggatctta caataatttc
1201 ttcagaatgt ttgacagaaa cacaaagcga gacataaccc tagaagcatc gcgggaaaac
1261 aataagcctc gcacagttct gaagcctcgc aaagtctgtg caagtggcaa gcgaaagaaa
1321 gatgaaataa gtgttgacag cctagacttc aataagaaaa tccttcacac agcctggcac
1381 cccaaggaaa atatcattgc cgtagctact acaaacaatc tgtatatatt tcaagacaaa
1441 gtgaattagg gttggcattc ctagcagaag aacccacttc ctgcttagtt gagatagttg
1501 aatctagcat tcgttcctat aaaagagaga ggtccattgt ggcgcccctt tccagtgttt
1561 gacagtgtgc cattcgacaa cacattgtta tagctacatg gagaaagctc tgtggattca
1621 tcactgtggt gttctccatg tctgctagcc atttaggtaa gggtagggca cttttaattt
1681 aaatgacttc ttgcaccatc ttgcctaatg gactagattg gactgtatca acattgattt
1741 actccacttt ttatgccttc cattgtgatg acgtcaaaca cagtgaaagc cttcagtcat
1801 gctatgggat ttaattgtgt atcctcatta ctgtatcatt tgtggggtac accccttccc
1861 ccttttttta aattaaatac agctcattct tactgtggct tgtagcattc ctcctcttct
1921 ggcctcctgg actgctcccc ttcatctctt acccttgccc cctccacccg gtcttggtgg
1981 tggtatatta aaaaaagaaa gaatgaaagc acacaaaatg agtcagtttg gggtcagtgg
2041 tataaagggg gtatatgttg caaacaaatg ttttagtaac agttggctgt aatcactcct
2101 cgccgtgtct ggcactgaaa ataaggaaaa g
//