LOCUS HUMPFK 1138 bp mRNA linear HUM 27-APR-1993
DEFINITION Human phosphofructokinase (PFK) mRNA, complete cds.
ACCESSION M64784
VERSION M64784.1
KEYWORDS phosphofructokinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1138)
AUTHORS Simpson,C.J. and Fothergill-Gilmore,L.A.
TITLE Isolation and sequence of a cDNA encoding human platelet
phosphofructokinase
JOURNAL Biochem. Biophys. Res. Commun. 180 (1), 197-203 (1991)
PUBMED 1834056
COMMENT Original source text: Human, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1138
/db_xref="H-InvDB:HIT000196148"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Raji"
/cell_type="lymphocyte"
gene 1..1138
/gene="PFK"
CDS <1..905
/gene="PFK"
/EC_number="2.7.1.11"
/codon_start=3
/product="phosphofructokinase"
/protein_id="AAA36435.1"
/translation="IPKYLEEIATQMRTSINALLIIGGFEAYLGLLELSAAREKHEEF
CVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGY
CGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSEN
YTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITEKLK
EARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKI
LAKYKASYDVSDSGQLEHVQPWSV"
regulatory 1104..1110
/regulatory_class="polyA_signal_sequence"
/gene="PFK"
BASE COUNT 302 a 293 c 301 g 242 t
ORIGIN Chromosome: 11.
1 gaattccgaa gtacttggaa gagatcgcca cacagatgcg caccagcatc aacgcgctgc
61 tgatcatcgg tggattcgag gcctacctgg gactcctgga gctgtcagcc gcccgggaga
121 agcacgagga gttctgtgtc cccatggtca tggttcccgc tactgtgtcc aacaatgtgc
181 cgggttccga tttcagcatc ggggcagaca ccgccctgaa cactatcacc gacacctgcg
241 accgcatcaa gcagtccgcc agcggaacca agcggcgcgt gttcatcatc gagaccatgg
301 gcggctactg tggctacctg gccaacatgg gggggctcgc ggccggagct gatgccgcat
361 acattttcga agagcccttc gacatcaggg atctgcagtc caacgtggag cacctgacgg
421 agaaaatgaa gaccaccatc cagagaggcc ttgtgctcag aaatgagagc tgcagtgaaa
481 actacaccac cgacttcatt taccagctgt attcagaaga gggcaaaggc gtgtttgact
541 gcaggaagaa cgtgctgggt cacatgcagc agggtggggc accctctcca tttgatagaa
601 actttggaac caaaatctct gccagagcta tggagtggat cactgaaaaa ctcaaggagg
661 cccggggcag aggaaaaaaa tttaccaccg atgattccat ttgtgtgctg ggaataagca
721 aaagaaacgt tatttttcaa cctgtggcag agctgaagaa gcaaacggat tttgagcaca
781 ggattcccaa agaacagtgg tggctcaagc tacggcccct catgaaaatc ctggccaagt
841 acaaggccag ctatgacgtg tcggactcag gccagctgga acatgtgcag ccctggagtg
901 tctgacccag tcccgcctgc atgtgcctgc agccaccgtg gactgtgtct gtttgtaaca
961 cttaagttat tttatcagca ctttatgcac gtattattga cattgaatac ctaatcggcg
1021 agtgcccatc tgccccacca gctcccagtg cgtgctgtct gtggagtgtg tctcatgctt
1081 tcagatgtga tatgagcaga attaattaaa catttgccta tgaaaaaaaa aaaaaaaa
//