LOCUS HUMCALD 2975 bp mRNA linear HUM 27-APR-1993
DEFINITION Human caldesmon mRNA, complete cds.
ACCESSION M64110
VERSION M64110.1
KEYWORDS F-actin binding protein; caldesmon; calmodulin; myosin;
tropomyosin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2975)
AUTHORS Novy,R.E., Lin,J.L. and Lin,J.J.
TITLE Characterization of cDNA clones encoding a human fibroblast
caldesmon isoform and analysis of caldesmon expression in normal
and transformed cells
JOURNAL J. Biol. Chem. 266 (25), 16917-16924 (1991)
PUBMED 1885618
COMMENT Original source text: Homo sapiens (library: lambda gt11) fetus
lung cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2975
/db_xref="H-InvDB:HIT000196100"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="WI-38"
/cell_type="fibroblast"
/tissue_type="lung"
/dev_stage="fetus"
/tissue_lib="lambda gt11"
CDS 112..1728
/codon_start=1
/product="caldesmon"
/protein_id="AAA35636.1"
/translation="MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRR
ARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLAR
REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY
EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKE
PKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQME
AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE
EADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIE
ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVP
AEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPK
PSDLRPGDVSSKRNLWEKQSVDKVTSPTKV"
BASE COUNT 1036 a 544 c 725 g 670 t
ORIGIN
1 cagatcatca aatcaaattc cacagggatt ggtgaccaac cagaaggctc agacatctga
61 ttgctgacct gtccagacat catctggtct ccctgaacct gaaatcacac catggatgat
121 tttgagcgtc gcagagaact tagaaggcaa aagagggagg agatgcgact cgaagcagaa
181 agaatcgcct accagaggaa tgacgatgat gaagaggagg cagcccggga acggcgccgc
241 cgagcccgac aggaacggct gcggcagaag caggaggaag aatccttggg acaggtgacc
301 gaccaggtgg aggtgaatgc ccagaacagt gtgcctgacg aggaggccaa gacaaccacc
361 acaaacactc aagtggaagg ggatgatgag gccgcattcc tggagcgcct ggctcggcgt
421 gaggaaagac gccaaaaacg ccttcaggag gctctggagc ggcagaagga gttcgaccca
481 acaataacag atgcaagtct gtcgctccca agcagaagaa tgcaaaatga cacagcagaa
541 aatgaaacta ccgagaagga agaaaaaagt gaaagtcgcc aagaaagata cgagatagag
601 gaaacagaaa cagtcaccaa gtcctaccag aagaatgatt ggagggatgc tgaagaaaac
661 aagaaagaag acaaggaaaa ggaggaggag gaagaggaga agccaaagcg agggagcatt
721 ggagaaaatc agatcaaaga tgaaaagatt aaaaaggaca aagaacccaa agaagaagtt
781 aagagcttca tggatcgaaa gaagggattt acagaagtta agtcgcagaa tggagaattc
841 atgacccaca aacttaaaca tactgagaat actttcagcc gccctggagg gagggccagc
901 gtggacacca aggaggctga gggcgccccc cagatggaag ccggcaaaag gctggaggag
961 cttcgtcgtc gtcgcgggga gaccgagagc gaagagttcg agaagctcaa acagaagcag
1021 caggaggcgg ctttggagct ggaggaactc aagaaaaaga gggaggagag aaggaaggtc
1081 ctggaggagg aagagcagag gaggaagcag gaggaagccg atcgaaaact cagagaggag
1141 gaagagaaga ggaggctaaa ggaagagatt gaaaggcgaa gagcagaagc tgctgagaaa
1201 cgccagaaga tgccagaaga tggcttgtca gatgacaaga aaccattcaa gtgtttcact
1261 cctaaaggtt catctctcaa gatagaagag cgagcagaat ttttgaataa gtctgtgcag
1321 aaaagcagtg gtgtcaaatc gacccatcaa gcagcaatag tctccaagat tgacagcaga
1381 ctggagcagt ataccagtgc aattgaggga acaaaaagcg caaaacctac aaagccggca
1441 gcctcggatc ttcctgttcc tgctgaaggt gtacgcaaca tcaagagtat gtgggagaaa
1501 gggaatgtgt tttcatcccc cactgcagca ggcacaccaa ataaggaaac tgctggcttg
1561 aaggtagggg tttctagccg catcaatgaa tggctaacta aaaccccaga tggaaacaag
1621 tcacctgctc ccaaaccttc tgacttgaga ccaggagacg tatccagcaa gcggaacctc
1681 tgggaaaagc aatctgtgga taaggtcact tcccccacta aggtttgaga cagttccaga
1741 aagaacccaa gctcaagacg caggacgagc tcagttgtag agggctaatt cgctctgttt
1801 tgtatttatg ttgatttact aaattgggtt cattatcttt tatttttcaa tatcccagta
1861 aacccatgta tattatcact atatttaata atcacagtct agagatgttc atggtaaaag
1921 tactgccttt gcacaggagc ctgtttctaa agaaacccat gctgtgaaat agagactttt
1981 ctactgatca tcataactct gtatctgagc agtgatacca accacatctg aagtcaacag
2041 aagatccaag tttaaaattg cctgcggaat gtgtgcagta tctagaaaaa tgaaccgtag
2101 tttttgtttt tttaaataca gaagtcatgt tgtttctgca ctttataata aagcatggaa
2161 gaaattatct tagtaggcaa ttgtaacact ttttgaaagt aacccatttc agatttgaaa
2221 tactgcaata atggttgtct ttaaaaaaaa aaaaaagaaa cgtactgtta aggtattact
2281 ttttttcatg ctgatgattc atatctaaat tacattatta tgttagctga cagtggtact
2341 gattttttag gttggttgtt ttgtggattt ctttagtagt gatagtagcc tgaaccacat
2401 tttagataac tcaattatgt atgtatgtgc atacacatat acaaacacac taatggtaga
2461 atgctttttt atgtgctaga ctattatatt tagtagtatg tcattgtaac tagccaatat
2521 cacagctttt gaaaaattaa aaaatcacac tatattaata tttcatattt gccaacagaa
2581 acatggcaga taggtatcaa tatgttttca atgcctgatg acctataaga agaaagtatt
2641 gaaaagaaga gagattagaa ctgttagaag gagttgaaat tttctaaaag acatagtatt
2701 tagtttataa ttaaatgcat tcttgaagtc cagtgtgaat tttattaatg ctatcatctc
2761 gaccaagctc aaagcctact tattagaaac aatgaagttc acaataggtc ataaggtctc
2821 ttccttttct aaaattgaaa gacaagaaat ttagtgccaa tattgtacag acagaaattc
2881 catgtatgag tctcaacaaa gactaccttt ggctaaatgt ctagaagcag agaagtaaag
2941 tgagcaaaat ccagtgttga ggagtcatgg aattc
//